B cell chronic lymphocytic leukemia with florid reactive CD4+ T cell lymphocytosis in lymph nodes.
Leuk Lymphoma
; 9(1-2): 153-6, 1993 Jan.
Article
em En
| MEDLINE
| ID: mdl-8097420
ABSTRACT
This case is of an unusual florid reactive CD4+ T Cell lymphocytosis involving lymph node (LN) and overshadowing residual B chronic lymphocytic leukemia (CLL). A 65 year old female with a 9 year history of untreated B-CLL presented with weight loss, splenomegaly and lymphadenopathy. B-CLL was confirmed on the basis of peripheral blood lymphocytosis, bone marrow trephine findings and flow cytometry analysis. However, the LN biopsy showed appearances of a diffuse small lymphocytic population mimicking a leukemic T-cell infiltrate. Immunophenotyping and molecular analysis demonstrated the major cell population to be reactive CD4 positive T lymphocytes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leucemia Linfocítica Crônica de Células B
/
Linfócitos T CD4-Positivos
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Linfocitose
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Linfonodos
Limite:
Aged
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Female
/
Humans
Idioma:
En
Revista:
Leuk Lymphoma
Ano de publicação:
1993
Tipo de documento:
Article