Tumorigenicity of a combination of psoriasis therapies.
Br J Cancer
; 69(6): 1043-5, 1994 Jun.
Article
em En
| MEDLINE
| ID: mdl-8198968
ABSTRACT
Coal tar, a tumour initiator, and dithranol, a tumour promoter, are used in the treatment of psoriasis. Topical treatment of mice with pharmaceutical formulations of these two agents, at therapeutic doses, induced skin papillomas in a classical two-stage carcinogenesis protocol, while treatment with either agent alone did not. This finding has implications for the use of both agents in combination in the treatment of psoriasis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psoríase
/
Neoplasias Cutâneas
/
Carcinógenos
/
Antralina
/
Alcatrão
Tipo de estudo:
Guideline
Limite:
Animals
Idioma:
En
Revista:
Br J Cancer
Ano de publicação:
1994
Tipo de documento:
Article