RNA interactions in the regulation of transcription.
Nucleic Acids Symp Ser
; (33): 1-4, 1995.
Article
em En
| MEDLINE
| ID: mdl-8643338
ABSTRACT
In this overview we describe interactions between RNA, DNA, and proteins that are involved in the regulation of the various functional cycles of E. coli transcription. The role of the RNA terminator hairpin in destabilizing the transcription elongation complex and controlling the efficiency of termination at various template positions near intrinsic terminators are discussed, as are the mechanisms whereby rho protein triggers RNA release at rho-dependent terminators. Mechanisms used by phage 1-coded antitermination factor N in "fine-tuning" termination efficiencies are also considered, as are the roles of kinetically different elongation complex conformations in controlling transcriptional fidelity. General principles of the control of transcription by such RNA-protein interaction mechanisms are discussed.
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Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
RNA Bacteriano
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Nucleic Acids Symp Ser
Ano de publicação:
1995
Tipo de documento:
Article