Benign versus malignant intraosseous lesions: discrimination by means of PET with 2-[F-18]fluoro-2-deoxy-D-glucose.
Radiology
; 200(1): 243-7, 1996 Jul.
Article
em En
| MEDLINE
| ID: mdl-8657920
ABSTRACT
PURPOSE:
To assess the ability of positron emission tomography (PET) with 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG) to allow differentiation of benign from malignant intraosseous lesions. MATERIALS ANDMETHODS:
Twenty patients with strictly intraosseous lesions (five benign and 15 malignant [three primary and 12 metastatic]) were studied with FDG PET. The final diagnosis was confirmed with histopathologic examination in all patients. The uptake of FDG within each lesion was evaluated qualitatively as well as semiquantitatively by determination of the standardized uptake value (SUV).RESULTS:
SUV assessment of FDG accumulation within osseous lesions was superior to subjective visual analysis for discriminating benign from malignant lesions. With use of a 2.0 cutoff value for SUV, 14 of 15 malignant lesions were categorized correctly versus 12 of 15 correctly categorized by means of subjective image evaluation; four of five benign lesions were categorized correctly with both techniques.CONCLUSION:
FDG PET can aid in differentiating benign from malignant strictly intraosseous lesions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Ósseas
/
Neoplasias Ósseas
/
Tomografia Computadorizada de Emissão
/
Meios de Contraste
/
Desoxiglucose
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Radiology
Ano de publicação:
1996
Tipo de documento:
Article