[Goodpasture's syndrome with negative renal immunofluorescence]. / Síndrome de Goodpasture con inmunofluorescencia renal negativa.

ABSTRACT

The diagnosis of Goodpasture's syndrome is established by the clinical setting of diffuse alveolar hemorrhage and glomerulonephritis, and the demonstration of circulating or tissue-bound antibasement membrane antibodies. However, cases of Goodpasture's syndrome limited either to the lungs or kidneys have been reported. The absence of immune deposits from renal biopsy specimens of a patient with Goodpasture's syndrome, even with normal renal function, is exceptional. We report here a case of Goodpasture's syndrome characterized by direct immunofluorescence staining of the transbronchial biopsy specimen, and with direct negative immunofluorescence on renal biopsy specimen.