Electrochemical behaviour of clenbuterol at Nafion-modified carbon-paste electrodes.
J Pharm Biomed Anal
; 14(1-2): 57-63, 1995 Dec.
Article
em En
| MEDLINE
| ID: mdl-8833967
ABSTRACT
A detailed study of the electrochemistry of clenbuterol at bare carbon-paste electrodes (CPEs) has been carried out. Results showed that clenbuterol undergoes an ECE process. This compound is irreversibly oxidised at high potentials, resulting in the formation of a product which demonstrates quasi-reversible electrochemical behaviour at less positive potentials. The amount of this chemical product formed is very pH-dependent. Investigations into the electrochemical behaviour of clenbuterol at Nafion-modified CPEs were also made. The use of a thin Nafion film cast over the CPE resulted in a large increase in peak current over bare electrodes. Linear accumulation occurred with time, the linear range increasing with decreasing concentration. This allowed the detection of low concentrations of clenbuterol. Diffusion proved to be the rate-controlling process of clenbuterol through the Nafion membrane.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Clembuterol
Idioma:
En
Revista:
J Pharm Biomed Anal
Ano de publicação:
1995
Tipo de documento:
Article