[Foveal cone densitometry in high myopia].
Nippon Ganka Gakkai Zasshi
; 100(3): 235-9, 1996 Mar.
Article
em Ja
| MEDLINE
| ID: mdl-8900590
ABSTRACT
We performed foveal cone densitometry using a modified fundus camera in 17 eyes of 17 normal subjects (age range, 20 to 47 yr, refractive error, +2.0 to -2.5 D) and 15 eyes of 15 high myopia subjects with normal visual acuity (age range, 18 to 46 yr, refractive error, -9.0 to -14.5 D). After fully bleaching, the density of photopigment was measured for 7 minutes by a test spot of 562 nm in wavelength and 1 degree in diameter, focussed on the fovea. Two-way density and the time constant of pigment regeneration were calculated. No significant difference was found in two-way density between the two groups. The time constant in high myopia (161.6 +/- 36.6 sec), however, was significantly increased (p < 0.01), compared with normals (124.0 +/- 28.7 sec). To study the correlation of psychophysical visual function, we performed a photostress recovery test, which revealed a significant delay of the recovery time in high myopia (p < 0.01). These results suggest that a delay in foveal cone pigment kinetics precedes loss of cone cells or chorioretinal degeneration in high myopia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células Fotorreceptoras Retinianas Cones
/
Fóvea Central
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Miopia
Limite:
Adolescent
/
Adult
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Female
/
Humans
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Male
/
Middle aged
Idioma:
Ja
Revista:
Nippon Ganka Gakkai Zasshi
Ano de publicação:
1996
Tipo de documento:
Article