Cytogenetic studies in coke oven workers.
Toxicol Lett
; 88(1-3): 185-9, 1996 Nov.
Article
em En
| MEDLINE
| ID: mdl-8920735
ABSTRACT
Chromosome aberrations, micronuclei, and sister chromatid exchanges (SCE) were evaluated in cultured lymphocytes of coke oven workers of an Italian steel industry plant, occupationally exposed to polycyclic aromatic hydrocarbons, and in a group of unexposed controls from a non-oven plant in the same area. No differences were found between exposed and controls for rates of total abnormal metaphases (including and excluding gaps), chromatid-type and chromosome-type aberrations, cells with 2 or more breaks, and for micronuclei. On the contrary, SCE were significantly increased in the exposed versus the controls, but, when smoking habits were considered, the increase was significant only for smokers.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Troca de Cromátide Irmã
/
Exposição Ocupacional
/
Aberrações Cromossômicas
/
Coque
/
Micronúcleos com Defeito Cromossômico
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Humans
/
Middle aged
Idioma:
En
Revista:
Toxicol Lett
Ano de publicação:
1996
Tipo de documento:
Article