[An experimental study of the effect of Zofran on the manifestations of a primary reaction to irradiation]. / Eksperimental'noe issledovanie vliianiia zofrana na proiavleniia pervichnoi reaktsii na obluchenie.

ABSTRACT

Zofran is a selective antagonist of 5-HT3 receptors which effectively prevents postradiation dyspeptic and behavioral disorders in dogs and rats. Administration of the drug normalizes intestinal absorption and propulsion activity in irradiated animals.