Hereditary ovarian cancer.
Curr Opin Obstet Gynecol
; 9(1): 3-7, 1997 Feb.
Article
em En
| MEDLINE
| ID: mdl-9090474
ABSTRACT
Ovarian cancer has been described in association with three autosomal dominant syndromes familial site-specific ovarian cancer, familial breast and ovarian cancer, and the hereditary nonpolyposis colon cancer syndrome. It appears that most breast-ovarian and site-specific ovarian cancer families are explained by mutations in the BRCA1 tumor suppressor gene. Other genes associated with inherited susceptibility to ovarian cancer include BRCA2, p53, and the DNA mismatch repair genes.
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Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Doenças Ovarianas
Limite:
Female
/
Humans
Idioma:
En
Revista:
Curr Opin Obstet Gynecol
Ano de publicação:
1997
Tipo de documento:
Article