Management of secretions in esophageal cancer patients with glycopyrrolate.

ABSTRACT

BACKGROUND: There has been little emphasis in the past upon management of excessive secretions in patients with esophageal cancer. We used the drug glycopyrrolate for controlling secretions in patients with esophageal cancer. PATIENTS AND METHODS: Between January 1991 and September 1995, 45 patients with esophagus cancer were referred for evaluation. Seven of these patients were treated with glycopyrrolate for increased secretions. Secretions were measured in suction canisters which were used by patients. RESULTS: All the patients showed a decrease in secretions within 24 48 hours of administration. The incidence of side effects was minimal. CONCLUSIONS: Glycopyrrolate is quite effective in palliating esophageal cancer patients with excessive secretions.