Selective IgG2 subclass deficiency--a marker for the syndrome of pre/postnatal growth retardation, developmental delay, hypotrophy of distal extremities, dental anomalies and eczema.
Clin Dysmorphol
; 6(2): 139-46, 1997 Apr.
Article
em En
| MEDLINE
| ID: mdl-9134294
ABSTRACT
We report a third family with members displaying pre- and postnatal growth retardation, hypotonia, psychomotor retardation, small puffy hands and feet, dental anomalies and eczematous skin. The four affected members are all females born to unrelated parents consistent with the previously proposed autosomal recessive mode of inheritance. We report a further clinical feature of selective immunoglobulin IgG2 subclass deficiency which would explain some of the clinical findings and might provide an immunological marker for diagnostic confirmation of the syndrome.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anormalidades Dentárias
/
Deficiências do Desenvolvimento
/
Deficiência de IgG
/
Eczema
/
Extremidades
/
Retardo do Crescimento Fetal
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
Idioma:
En
Revista:
Clin Dysmorphol
Ano de publicação:
1997
Tipo de documento:
Article