RNA editing: getting U into RNA.
Trends Biochem Sci
; 22(5): 162-6, 1997 May.
Article
em En
| MEDLINE
| ID: mdl-9175474
ABSTRACT
RNA editing in kinetoplastid protozoa remodels the sequences of mitochondrial pre-mRNAs by the precise insertion and deletion of uridylate residues. These sequence changes are directed by small trans-acting RNAs, termed guide RNAs. The basic mechanistic pathway by which edited RNA is generated has recently been elucidated using in vitro systems capable of a full round of guide-RNA-directed editing.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Uridina Monofosfato
/
Edição de RNA
Idioma:
En
Revista:
Trends Biochem Sci
Ano de publicação:
1997
Tipo de documento:
Article