Immunogenetic and oncogenic properties of rat trophoblast cell lines.
Am J Reprod Immunol
; 38(3): 158-61, 1997 Sep.
Article
em En
| MEDLINE
| ID: mdl-9325486
ABSTRACT
PROBLEM:
The nature of major histocompatibility complex (MHC) antigen expression on rat placentas, trophoblast cell lines, and tumors derived from trophoblast cells was explored. METHOD OF STUDY Cytohistochemical and flow cytometric analysis and molecular techniques.RESULTS:
MHC antigen expression and genomic imprinting on the placenta and on trophoblast cells varies with the time of gestation and with the type of MHC antigen.CONCLUSIONS:
There is no correlation in trophoblast cells between class I expression and cell ploidy, on the one hand, and malignant potential, on the other hand. Genomic imprinting of class I antigens in the rat placenta is a quantitative phenomenon.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trofoblastos
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Am J Reprod Immunol
Ano de publicação:
1997
Tipo de documento:
Article