[Cerebral sinus thrombosis: rapid test diagnosis by demonstration of increased plasma D-dimer levels (SimpliRED)]. / Zerebrale Sinusthrombose--Schnelltest-Diagnostik mittels Nachweis erhöhter D-dimer Konzentrationen im Plasma (SimpliRED).
Rofo
; 167(5): 527-9, 1997 Nov.
Article
em De
| MEDLINE
| ID: mdl-9440901
ABSTRACT
PURPOSE:
To perform an initial evaluation of the accuracy in detection of dural sinus and cerebral venous thrombosis using a bed-side test (SimpliRED). MATERIAL ANDMETHODS:
Early diagnosis and treatment of cerebral sinus thrombosis are important. A screening test to decide which patients should undergo further diagnostics would be valuable due to the low incidence. Six patients with MR proven cerebral sinus thrombosis underwent bed-side testing. The SimpliRED kit provides a clearly visible agglutination of the patient's red blood cells in the presence of elevated levels of the crosslinked fibrin derivative (D-dimer) in the sample.RESULTS:
The assay yielded a positive result in all six patients, even 56 days following the onset of clinical symptoms.CONCLUSION:
The sensitivity of SimpliRED in the detection of sinus venous thrombosis is not known. This assay, therefore, should be evaluated in a large prospective study. In addition, the capability of the test to assess the effect of and predict the duration of anticoagulation therapy should be considered.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trombose dos Seios Intracranianos
/
Produtos de Degradação da Fibrina e do Fibrinogênio
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
De
Revista:
Rofo
Ano de publicação:
1997
Tipo de documento:
Article