Iodine and hypothyroidism in neonates with congenital heart disease.
Arch Dis Child Fetal Neonatal Ed
; 77(3): F239-40, 1997 Nov.
Article
em En
| MEDLINE
| ID: mdl-9462198
ABSTRACT
AIM:
To evaluate the influence of the intravenous injection of iodine during cardiac catheterisation, and of topical iodine antiseptics during surgical procedures, on thyroid function in full term neonates.METHODS:
Twenty one full term infants with major cardiac anomalies who survived for more than a month were studied. Thyroxine and thyrotropin concentrations were measured (by radioimmunoassay) before each procedure, 24 hours after the procedure, and every week thereafter until the age of 1 month or until normal. Thyroxine values less than 64.4 nmol/l were considered low, while thyrotropin values greater than 30 mU/l were considered high.RESULTS:
Thyroid function tests before iodine exposure were within normal limits in all infants. Following catheterisation or surgery six infants had raised thyrotropin concentrations; three had low thyroxine concentrations. Two of those infants were treated with L-thyroxine.CONCLUSION:
Iodine exposure during cardiac catheterisation or surgery may induce transient hypothyroidism in term infants.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cardiopatias Congênitas
/
Hipotireoidismo
/
Iodo
Tipo de estudo:
Observational_studies
Limite:
Humans
/
Newborn
Idioma:
En
Revista:
Arch Dis Child Fetal Neonatal Ed
Ano de publicação:
1997
Tipo de documento:
Article