Multi-start downhill simplex method for spatio-temporal source localization in magnetoencephalography.
Electroencephalogr Clin Neurophysiol
; 108(1): 32-44, 1998 Jan.
Article
em En
| MEDLINE
| ID: mdl-9474060
ABSTRACT
A multi-start downhill simplex method is examined as a global minimization technique for fitting multidipole, spatio-temporal magnetoencephalography (MEG) data. This procedure has been performed on both simulated and empirical human visual data, known to exhibit complex field patterns due to multiple sources. Unlike some other non-linear fitting techniques the multi-start downhill simplex method does not require users to provide initial guesses for the dipole parameters, hence the fitting procedure is less time-consuming, more objective, and user-friendly. In addition, this method offers more than one adequate solution thus providing a range of uncertainty for the estimated parameters. The Multi-start downhill simplex method is used to fit the non-linear dipole spatial parameters, while the linear temporal parameters are fit using a separate linear fitting procedure. Singular value decomposition (SVD) is also used in order to improve the procedure for determining the adequate number of modeled dipoles.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Córtex Visual
/
Mapeamento Encefálico
/
Magnetoencefalografia
/
Modelos Neurológicos
Limite:
Humans
Idioma:
En
Revista:
Electroencephalogr Clin Neurophysiol
Ano de publicação:
1998
Tipo de documento:
Article