[Chronic HIV- and chronic HBV infection with hematuria and proteinuria]. / Chronische HIV- und chronische HBV-Infektion mit Erythrozyturie und Proteinurie.
Dtsch Med Wochenschr
; 123(7): 185-8, 1998 Feb 13.
Article
em De
| MEDLINE
| ID: mdl-9505944
HISTORY AND CLINICAL FINDINGS: A medical examination, undertaken in an apparently healthy 30-year-old man because of his occupational exposure to chemicals, revealed haematuria and proteinuria. Physical examination was unremarkable except for oral hair-leukoplakia and swelling of the cervical, supraclavicular, axillary and inguinal lymph nodes. INVESTIGATIONS: Examination of the urine demonstrated selective glomerular proteins (1.5 g/24 h) and dysmorphic erythrocytes. SGOT and SGPT activities were raised (73 and 129 IU/l, respectively). Active hepatitis B virus (HBV) and human immunodeficiency virus (HIV-1) infections were demonstrated virologically. The CD4+ count in blood was reduced to 200 cells/microliter. Renal biopsy showed an IgA nephropathy. TREATMENT AND COURSE: Antiretroviral treatment with zidovudine and lamivudine were started. SGOT and SGPT activities and HIV load fell steadily, while CD4+ cell count rose markedly. Renal functions have remained stable during the past 6 months. CONCLUSION: Signs of glomerular damage are not unusual in systemic diseases, tumors or infections (Hepatitis B and HIV in this case) and they may be the first manifestations of the underlying disease.
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Coleções:
01-internacional
Contexto em Saúde:
12_ODS3_hazardous_contamination
/
15_ODS3_global_health_risks
/
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Proteinúria
/
Monitoramento Ambiental
/
Síndrome da Imunodeficiência Adquirida
/
HIV-1
/
Hematúria
/
Hepatite B
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
De
Revista:
Dtsch Med Wochenschr
Ano de publicação:
1998
Tipo de documento:
Article