Granulocytic ehrlichiosis in tick-immune guinea pigs.

Das, S; Deponte, K; Marcantonio, N L; Ijdo, J W; Hodzic, E; Katavolos, P; Barthold, S W; Telford, S R; Kantor, F S; Fikrig, E

Das, S; Deponte, K; Marcantonio, N L; Ijdo, J W; Hodzic, E; Katavolos, P; Barthold, S W; Telford, S R; Kantor, F S; Fikrig, E.

Afiliação

Das S; Department of Internal Medicine, Yale University, New Haven, Connecticut 06520-8031, USA.

Infect Immun ; 66(4): 1803-5, 1998 Apr.

Article em En | MEDLINE | ID: mdl-9529119

ABSTRACT

ABSTRACT

We investigated whether Ixodes scapularis-mediated host immunity interrupts transmission of the agent of human granulocytic ehrlichiosis (aoHGE) to guinea pigs. Ticks infected with aoHGE readily transmitted aoHGE to tick-immune guinea pigs, despite incomplete tick engorgement and host attachment. Although tick immunity can prevent Lyme borreliosis, protection is not afforded against granulocytic ehrlichiosis.

Assuntos

Ehrlichiose/prevenção & controle; Ixodes/imunologia; Animais; Ehrlichiose/transmissão; Feminino; Cobaias; Células HL-60; Humanos; Immunoblotting; Camundongos; Camundongos Endogâmicos C3H; Camundongos SCID; Reação em Cadeia da Polimerase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ehrlichiose / Ixodes Limite: Animals / Female / Humans Idioma: En Revista: Infect Immun Ano de publicação: 1998 Tipo de documento: Article

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