[Rubella in Russia: the detection of congenital rubella and the vaccination strategy and procedures]. / Krasnukha v Rossii: vyiavlenie vrozhdennoi krasnukhi, strategiia i taktika vaktsinatsii.
Zh Mikrobiol Epidemiol Immunobiol
; (1): 46-9, 1998.
Article
em Ru
| MEDLINE
| ID: mdl-9532685
ABSTRACT
The work on the evaluation of the role of rubella infection in the development of congenital malformations in newborn infants, as well as the immunogenic activity and tolerability of live attenuated vaccine Rudivax (Pasteur Mérieux Connaught) was carried out in the process of selective immunization in the Perm region. The study made it possible to find out 15% of malformations in the structure of the congenital pathology of newborn infants, which appeared due to the infection of the fetus with rubella virus and were manifested by multiple development defects, congenital C.N.S. defects and valvular defects. The results of using vaccine Rudivax in the epidemiological trial demonstrated that the vaccine had high immunological activity and was well tolerated. The absence of postvaccinal complications after the injection of the live vaccine and the absence of the extinction of immunity in the presence antibodies were indicative of the possibility vaccination without preliminary serological examination.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rubéola (Sarampo Alemão)
/
Vacina contra Rubéola
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Infant
/
Newborn
País/Região como assunto:
Asia
/
Europa
Idioma:
Ru
Revista:
Zh Mikrobiol Epidemiol Immunobiol
Ano de publicação:
1998
Tipo de documento:
Article