Analysis of recovery time indexes in 5-fluorouracil-treated cancer patients.
Oncol Rep
; 5(3): 645-7, 1998.
Article
em En
| MEDLINE
| ID: mdl-9538168
ABSTRACT
Based on our previous experience in doxorubicin-treated patients, in whom we observed a significant increase of ventricular recovery time indexes, we analyzed these non- invasive parameters of myocardium electrical instability in forty-three 5-fluorouracil-treated patients, to test the hypothesis of a mechanoelectrical disarrangement occurring in 5-fluorouracil (5FU) cardiotoxicity. All patients enrolled were studied at the first presentation and following chemotherapy. The study showed the absence of any significant changes in recovery time indexes or in other electrocardiographic parameters. Our data suggest that 5FU does not interfere with electrical properties of myocardial fibers.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Função Ventricular
/
Fluoruracila
/
Ventrículos do Coração
/
Neoplasias
/
Antimetabólitos Antineoplásicos
Tipo de estudo:
Observational_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Oncol Rep
Ano de publicação:
1998
Tipo de documento:
Article