Endemic infection with HTLV-IIB in Venezuelan Indians: molecular characterization.
J Acquir Immune Defic Syndr Hum Retrovirol
; 17(5): 458-64, 1998 Apr 15.
Article
em En
| MEDLINE
| ID: mdl-9562049
ABSTRACT
The peripheral blood of 41 Yaruro and Guahibo Indians from Venezuela was examined for HTLV antibodies and DNA. Twenty-five samples (61%) were found to be infected with HTLV-IIB. The sensitivities of the serologic and DNA polymerase chain reaction (PCR) analyses were 80% and 96%, respectively. Epidemiologic studies supported both sexual and perinatal transmission of the virus. Sequence analyses of the HTLV-IIB strains from these Indians indicate that they are unique relative to HTLV-II detected in other groups of humans. HTLV-IIB-G2 isolated from a Guahibo Indian is the most divergent HTLV-IIB strain relative to the prototype HTLV-II NRA.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vírus Linfotrópico T Tipo 2 Humano
/
Infecções por HTLV-II
/
Indígenas Sul-Americanos
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Animals
/
Humans
/
Middle aged
País/Região como assunto:
America do sul
/
Venezuela
Idioma:
En
Revista:
J Acquir Immune Defic Syndr Hum Retrovirol
Ano de publicação:
1998
Tipo de documento:
Article