Estimation of apoptosis in C6 glioma cells treated with antidepressants.
Physiol Res
; 46(2): 161-4, 1997.
Article
em En
| MEDLINE
| ID: mdl-9727508
ABSTRACT
Gel electrophoresis of DNA was used for estimation of DNA changes caused in C6 glioma cells by treatment with psychotropic drugs (imipramine, amitryptiline and fluoxetine). Some discrete bands containing a population of short DNA fragments appeared after 1 and 5 days of cultivation. Apoptotic DNA breaks were verified at single cell level using the TUNEL test in cells treated with fluoxetine.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Apoptose
/
Glioma
/
Imipramina
/
Antidepressivos
Limite:
Humans
Idioma:
En
Revista:
Physiol Res
Ano de publicação:
1997
Tipo de documento:
Article