A catalogue of imprinted genes and parent-of-origin effects in humans and animals.
Hum Mol Genet
; 7(10): 1599-609, 1998.
Article
em En
| MEDLINE
| ID: mdl-9735381
Parent-of-origin effects were first recorded >3000 years ago by mule breeders in Asia Minor. There are now several different types of evidence suggesting the presence of a large number of imprinted genes, many of which have not yet been identified. Here, we catalogue a wide range of evidence and phenomena which indicate or suggest the presence of genomic imprinting in animals. This evidence includes: the direct documentation of parent-of-origin-specific gene transcription; human disease inheritance patterns which suggest the involvement of imprinted genes; and older, less well studied animal models which may show parent-of-origin effects.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Impressão Genômica
Limite:
Animals
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Hum Mol Genet
Ano de publicação:
1998
Tipo de documento:
Article