Investigation into the cercariacidal and miracidiacidal properties of Endod (Phytolacca dodecandra) berries (type 44).
East Afr Med J
; 75(5): 311-4, 1998 May.
Article
em En
| MEDLINE
| ID: mdl-9747006
ABSTRACT
Aqueous extract of ground Endod (Phytolacca dodecandra) berries (Type 44) was investigated for its cercariacidal and miracidiacidal properties. Aqueous extract of the berries prevented snails from being infected by miracidia at a concentration of 4 ppm. Assessment of cercariacidal activity of Endod berries indicated that mortality of cercariae exposed to aqueous extract of Endod berries increased with increase in concentration of the test material and exposure time. Viability assessment test showed that pre-treatment of the cercariae with 12 ppm of the extract completely inhibited infection of mice by cercariae and significantly reduced tissue egg deposition and worm establishment in the mice (ANOVA, P < 0.05) The potential use of (Phytolacca dodecandra) berries against schistosome larval stages in fresh water in a schistosomiasis control program is discussed.
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Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Plantas Medicinais
/
Esquistossomose mansoni
/
Extratos Vegetais
/
Medicinas Tradicionais Africanas
/
Frutas
/
Fitoterapia
Limite:
Animals
País/Região como assunto:
Africa
Idioma:
En
Revista:
East Afr Med J
Ano de publicação:
1998
Tipo de documento:
Article