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Combined transfacial and neurosurgical approach to malignant tumours of the ethmoid sinus.
Salvan, D; Julieron, M; Marandas, P; Janot, F; Leridant, A M; Domenge, C; Mamelle, G; Schwaab, G; Luboinski, B.
Afiliação
  • Salvan D; Department of Otorhinolaryngology-Head and Neck Surgery, Institute Gustave Roussy, Villejuif, France.
J Laryngol Otol ; 112(5): 446-50, 1998 May.
Article em En | MEDLINE | ID: mdl-9747472
ABSTRACT
In order to understand the risks and benefits of a combined transfacial and neurosurgical procedure for neoplasms of the ethmoid sinus, we reviewed all patients who underwent this surgical approach in our department between 1986 and 1994. The study included 41 patients. Pathological diagnoses included adenocarcinoma (31 patients), squamous cell carcinoma (three patients), aesthesioneuroblastoma (three patients), other (four patients). The overall morbidity rate was 39 per cent, and the post-operative mortality rate was 2.5 per cent. Complications were statistically more likely in patients with bone skull base reconstruction. The main carcinologic failures were local recurrences (24 per cent) and metastases (22 per cent). The one-year, three-year and five-year Kaplan Meir survival rates were respectively 84 per cent, 53 per cent and 36 per cent. In conclusion, the mortality and morbidity were acceptable, especially when no bone skull base reconstruction was performed. Better local control justifies a combined procedure with post-operative radiotherapy when tumours involve or reach the skull base.
Assuntos
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Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias dos Seios Paranasais / Adenocarcinoma / Seio Etmoidal Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Laryngol Otol Ano de publicação: 1998 Tipo de documento: Article
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Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias dos Seios Paranasais / Adenocarcinoma / Seio Etmoidal Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Laryngol Otol Ano de publicação: 1998 Tipo de documento: Article