Role of the CNS microvascular pericyte in the blood-brain barrier.
J Neurosci Res
; 53(6): 637-44, 1998 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-9753191
ABSTRACT
Pericytes are a very important cellular constituent of the blood-brain barrier. They play a regulatory role in brain angiogenesis, endothelial cell tight junction formation, blood-brain barrier differentiation, as well as contribute to the microvascular vasodynamic capacity and structural stability. Central nervous system pericytes express macrophage functions and are actively involved in the neuroimmune network operating at the blood-brain barrier. They exhibit unique functional characteristics critical for the pathogenesis of a number of cerebrovascular, neurodegenerative, and neuroimmune diseases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Barreira Hematoencefálica
/
Circulação Cerebrovascular
/
Pericitos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Neurosci Res
Ano de publicação:
1998
Tipo de documento:
Article