[5HT-moduline an new peptide specifically interactive with the serotonergic system: physiopathologic implications]. / La 5HT-moduline, un nouveau peptide endogène interagissant spécifiquement avec le système sérotonergique: implications physiopathologiques.

5-HT1B receptors play a specific role as one of the many receptors regulating serotonergic activity. This endogenous peptide was recently isolated and characterized. Specific interaction has been demonstrated. 5-HT-moduline appears to be implicated in central nervous system response to various stimuli, particularly stress. It might play an important role in adaptation/inadaptation mechanisms (stress, anxiety, depression).