[Effect of brain edema on the recurrence pattern of malignant gliomas]. / Einfluss des Hirnödems auf das Rezidivwachstum maligner Gliome.
Radiologe
; 38(11): 948-53, 1998 Nov.
Article
em De
| MEDLINE
| ID: mdl-9861656
ABSTRACT
PURPOSE:
To assess the influence of initial preoperative brain edema in malignant gliomas on regrowth patterns. SUBJECTS ANDMETHODS:
79 patients with histologically verified supratentorial malignant glioma were prospectively studied by magnetic resonance imaging (MRI) before and every 2-3 months after surgery. The median follow-up time was 11 months. We correlated the configuration of the initial vasogenic edema on T2-weighted images with tumor regrowth patterns on contrast-enhanced T1-weighted images.RESULTS:
35/47 tumor regrowths (75%) imitated the initial edema configuration, while 11/47 occurred within the initial tumor bed; in one case tumor recurrence was multilocal.CONCLUSION:
In glioblastoma, tumor regrowth patterns correlate positively with the configuration of the initial vasogenic brain edema. The initial, "presurgical" peritumoral edema should thus be considered when planning further treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Edema Encefálico
/
Neoplasias Encefálicas
/
Imageamento por Ressonância Magnética
/
Glioma
/
Recidiva Local de Neoplasia
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
De
Revista:
Radiologe
Ano de publicação:
1998
Tipo de documento:
Article