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Caliciviruses in hospitalized children, São Luís, Maranhão, 1997-1999: detection of norovirus GII.12
Portal, Thayara Morais; Siqueira, Jones Anderson Monteiro; Costa, Larissa Cristina Prado das Neves; Lima, Ian Carlos Gomes de; Lucena, Maria Silvia Sousa de; Bandeira, Renato da Silva; Linhares, Alexandre da Costa; Luz, Claudia Regina Nunes Eloi da; Gabbay, Yvone Benchimol; Resque, Hugo Reis.
Afiliação
  • Portal, Thayara Morais; Universidade do Estado do Pará. Belém. Brazil
  • Siqueira, Jones Anderson Monteiro; Instituto Evandro Chagas. Ananindeua. Brazil
  • Costa, Larissa Cristina Prado das Neves; Faculdade Integrada Brasil Amazônia. Belém. Brazil
  • Lima, Ian Carlos Gomes de; Instituto Evandro Chagas. Seção de Virologia. Ananindeua. Brazil
  • Lucena, Maria Silvia Sousa de; Instituto Evandro Chagas. Seção de Virologia. Ananindeua. Brazil
  • Bandeira, Renato da Silva; Instituto Evandro Chagas. Seção de Virologia. Ananindeua. Brazil
  • Linhares, Alexandre da Costa; Instituto Evandro Chagas. Seção de Virologia. Ananindeua. Brazil
  • Luz, Claudia Regina Nunes Eloi da; Universidade Federal do Maranhão. São Luís. Brazil
  • Gabbay, Yvone Benchimol; Instituto Evandro Chagas. Seção de Virologia. Ananindeua. Brazil
  • Resque, Hugo Reis; Instituto Evandro Chagas. Seção de Virologia. Ananindeua. Brazil
Braz. J. Microbiol. ; 47(3): 724-730, Jul-Set. 2016. tab, ilus
Artigo em Inglês | VETINDEX | ID: vti-23461
Biblioteca responsável: BR68.1
Localização: BR68.1
ABSTRACT
Gastroenteritis is one of the most common diseases during childhood, with norovirus (NoV) and sapovirus (SaV) being two of its main causes. This study reports for the first time the incidence of these viruses in hospitalized children with and without gastroenteritis in São Luís, Maranhão. A total of 136 fecal samples were tested by enzyme immunoassays (EIA) for the detection of NoV and by reverse transcription-polymerase chain reaction (RT-PCR) for detection of both NoV and SaV. Positive samples for both agents were subjected to sequencing. The overall frequency of NoV as detected by EIA and RT-PCR was 17.6% (24/136) and 32.6% (15/46), respectively in diarrheic patients and 10.0% (9/90) in non-diarrheic patients (p 0.01). Of the diarrheic patients, 17% had fever, vomiting and anorexia, and 13% developed fever, vomiting and abdominal pain. Of the 24 NoV-positive samples, 50% (12/24) were sequenced and classified as genotypes GII.3 (n = 1), GII.4 (6), GII.5 (1), GII.7 (2), GII.12 (1) and GII.16 (1). SaV frequency was 9.8% (11/112), with 22.6% (7/31) in diarrheic patients and 4.9% (4/81) in nondiarrheic (p = 0.04) ones. In diarrheic cases, 27.3% had fever, vomiting and anorexia, whereas 18.2% had fever, anorexia and abdominal pain. One SaV-positive sample was sequenced and classified as GII.1. These results show a high genetic diversity of NoV and higher prevalence of NoV compared to SaV. Our data highlight the importance of NoV and SaV as enteropathogens in São Luís, Maranhão.(AU)
Assuntos


Texto completo: Disponível Base de dados: VETINDEX Assunto principal: Infecções por Caliciviridae / Gastroenterite Limite: Animais Idioma: Inglês Revista: Braz. J. Microbiol. Ano de publicação: 2016 Tipo de documento: Artigo

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Texto completo: Disponível Base de dados: VETINDEX Assunto principal: Infecções por Caliciviridae / Gastroenterite Limite: Animais Idioma: Inglês Revista: Braz. J. Microbiol. Ano de publicação: 2016 Tipo de documento: Artigo