Enterotoxigenic and non-enterotoxigenic Bacteroides fragilis from fecal microbiota of children

Enterotoxigenic Bacteroides fragilis (ETBF) is an important part of the human and animal intestinal microbiota and is commonly associated with diarrhea. ETBF strains produce an enterotoxin encoded by the bft gene located in the B. fragilis pathogenicity island (BfPAI). Non-enterotoxigenic B. fragilis (NTBF) strains lack the BfPAI and usually show two different genetic patterns, II and III, based on the absence or presence of a BfPAI-flanking region, respectively. The incidence of ETBF and NTBF strains in fecal samples isolated from children without acute diarrhea or any other intestinal disorders was determined. All 84 fecal samples evaluated were B. fragilis-positive by PCR, four of them harbored the bft gene, 27 contained the NTBF pattern III DNA sequence, and 52 were considered to be NTBF pattern II samples. One sample was positive for both ETBF and NTBF pattern III DNA sequences. All 19 B. fragilis strains isolated by the culture method were bft-negative, 9 belonged to pattern III and 10 to pattern II. We present an updated overview of the ETBF and NTBF incidence in the fecal microbiota of children from Sao Paulo City, Brazil.(AU)

Clostridium perfringens e a enterite necrótica em frangos: principais fatores de virulência, genéticos e moleculares

Clostridium perfringens é o causador da enterite necrótica que afeta a produção de frangos de corte no mundo todo. Essa bactéria produz diversas toxinas e causa lesões no intestino, tendo como consequências a elevada mortalidade e perdas econômicas devido à baixa produtividade. Nesta revisão são apresentados os principais fatores de virulência, a susceptibilidade aos antimicrobianos e a diversidade genética de C. perfringens isolados de frangos com enterite necrótica.(AU)

Clostridium perfringens cause necrotic enteritis affecting the poultry production worldwide. This bacterium produces various toxins and causes lesions in the intestine producing high mortality and economic loss due to the low productivity.In this review, the major virulence factors, antimicrobial susceptibility and genetic diversity of C. perfringens from chickens with necrotic enteritis are showed.(AU)

Clostridium perfringens e a enterite necrótica em frangos: principais fatores de virulência, genéticos e moleculares

Clostridium perfringens é o causador da enterite necrótica que afeta a produção de frangos de corte no mundo todo. Essa bactéria produz diversas toxinas e causa lesões no intestino, tendo como consequências a elevada mortalidade e perdas econômicas devido à baixa produtividade. Nesta revisão são apresentados os principais fatores de virulência, a susceptibilidade aos antimicrobianos e a diversidade genética de C. perfringens isolados de frangos com enterite necrótica.

Clostridium perfringens cause necrotic enteritis affecting the poultry production worldwide. This bacterium produces various toxins and causes lesions in the intestine producing high mortality and economic loss due to the low productivity.In this review, the major virulence factors, antimicrobial susceptibility and genetic diversity of C. perfringens from chickens with necrotic enteritis are showed.