Effects of milk from goat fed Crotalaria spectabilis seeds on growing rats / Efeitos da administração de ração contendo leite de cabra alimentada com sementes de Crotalaria spectabilis a ratos em crescimento

Seeds of Crotalaria spectabilis, containing the pyrrolizidine alkaloid (PA) monocrotaline (MCT), were fed to a lactating dairy goat. Milk from this goat was fed to rats for 8 weeks to determine whether MCT or its toxic metabolites are transferred into the goat's milk. Rats from the experimental group showed significantly higher (p<0.05) serum levels of ALT, AST, GGT and LDH and less weight gains (p<0.05) than control rats. The most significant lesions in rats consuming the experimental ration were mild to moderate interstitial pneumonia and a vacuolar degeneration and occasionally necrosis of periportal hepatocytes. The results of this study indicate that the PA and/or its metabolites are eliminated in milk.(AU)

Bronchoesophageal fistula in sheep: case report / Fístula broncoesofágica em ovino: relato de caso

The term bronchoesophageal fistula is used for the abnormal communication between the esophageal lumen and the pulmonary bronchi. There are no reports of this condition in production animals, and its origin is unknown. A male Dorper sheep from the Veterinary Hospital of the Santo Amaro University, SP, Brazil, presented clinical signs of tachypnea, apathy, and coughing after eating. The animal died suddenly after a fever break. During the gross evaluation, a fistula was noticed in the middle third of the thoracic esophagus with communication to the right cranial lung lobe, forming an encapsulated area measuring 24.5 cm x 22.0 cm x 9.4 cm. Fibrous tissue delimited the pulmonary lobe and feed filled the compartment. This is a rare condition with unclear etiopathogenesis.(AU)

O termo fístula broncoesofágica denomina a comunicação anormal entre o lúmen esofágico e os brônquios pulmonares. Não há relatos dessa condição em animais de produção, e sua origem é desconhecida. Um ovino macho da raça Dorper, proveniente do Hospital Veterinário da Universidade Santo Amaro, SP, Brasil, apresentou sinais clínicos de taquipneia, apatia e tosse após a alimentação. O animal morreu repentinamente após quadro febril. Na avaliação macroscópica notou-se fístula no terço médio do esôfago torácico com comunicação para o lobo pulmonar cranial direito, formando uma área encapsulada medindo24,5 cm x 22,0 cm x 9,4 cm. Tecido fibroso delimitava o lobo pulmonar e conteúdo alimentar preenchia o compartimento. Esta é uma condição rara com etiopatogenia incerta.(AU)