Interpretation of coagulation tendency contributing to thrombosis in vector-borne diseases (ehrlichiosis, anaplasmosis, leishmaniosis, and dirofilariasis) among dogs

Background: Vector-borne infectious and zoonotic diseases are an important health problem that directly affects human and animal health negatively. Results through evaluation of coagulation disorders among vector-borne diseases should be of beneficial for both human and dogs studies. According to the present authors knowledge reports regarding changes in platelet (PLT) count, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and D-dimer levels in dogs naturally infected with one or more vector-borne pathogens are lacking. Therefore, the present study was aimed to detecting those parameters for relation between diagnosis and prognosis of vector-borne diseases among dogs. Materials, Methods & Results: The material of this study was 46 dogs (36 were naturally infected with vector-borne diseases and 10 were healthy) from different breed, age and of both sexes. Venous blood samples were obtained to detect PLT counts, antibodies of ehrlichiosis, anaplasmosis, borreliosis, leishmaniosis and antigens of Dirofilaria immitis. The diagnosis of vector-borne diseases was performed by using a commercial ELISA assay kits. PLT count was performed with an automated blood cell counter analyser. In addition, PT, APTT and FIB concentrations were measured using a microcoagulometer. D-dimer concentrations were determined using fluorescence immunoassay rapid quantitave test analyser. Subgroups were formed according to the number of cases and the distribution of vector-borne agent. Statistically significant decreased PLT count was found in dogs mono infected with ehrlichiosis compared to healthy dogs (P < 0.001). Changes in mean PT value in the studied animals did not show statistically significant differences among the groups (P > 0.05). APTT values in the ehrlichiosis mono infection group were significantly higher than that of the healthy control (P < 0.01). A significant increase in FIB levels were detected […](AU)

Interpretation of coagulation tendency contributing to thrombosis in vector-borne diseases (ehrlichiosis, anaplasmosis, leishmaniosis, and dirofilariasis) among dogs

Background: Vector-borne infectious and zoonotic diseases are an important health problem that directly affects human and animal health negatively. Results through evaluation of coagulation disorders among vector-borne diseases should be of beneficial for both human and dogs studies. According to the present author’s knowledge reports regarding changes in platelet (PLT) count, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and D-dimer levels in dogs naturally infected with one or more vector-borne pathogens are lacking. Therefore, the present study was aimed to detecting those parameters for relation between diagnosis and prognosis of vector-borne diseases among dogs. Materials, Methods & Results: The material of this study was 46 dogs (36 were naturally infected with vector-borne diseases and 10 were healthy) from different breed, age and of both sexes. Venous blood samples were obtained to detect PLT counts, antibodies of ehrlichiosis, anaplasmosis, borreliosis, leishmaniosis and antigens of Dirofilaria immitis. The diagnosis of vector-borne diseases was performed by using a commercial ELISA assay kits. PLT count was performed with an automated blood cell counter analyser. In addition, PT, APTT and FIB concentrations were measured using a microcoagulometer. D-dimer concentrations were determined using fluorescence immunoassay rapid quantitave test analyser. Subgroups were formed according to the number of cases and the distribution of vector-borne agent. Statistically significant decreased PLT count was found in dogs mono infected with ehrlichiosis compared to healthy dogs (P 0.05). APTT values in the ehrlichiosis mono infection group were significantly higher than that of the healthy control (P < 0.01). A significant increase in FIB levels were detected […]

Interpretation of Coagulation Tendency Contributing to Thrombosis in Vector-Borne Diseases (Ehrlichiosis, Anaplasmosis, Leishmaniosis, and Dirofilariasis) among Dogs

Background: Vector-borne infectious and zoonotic diseases are an important health problem that directly affects human and animal health negatively. Results through evaluation of coagulation disorders among vector-borne diseases should be of beneficial for both human and dogs studies. According to the present authors knowledge reports regarding changes in platelet (PLT) count, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and D-dimer levels in dogs naturally infected with one or more vector-borne pathogens are lacking. Therefore, the present study was aimed to detecting those parameters for relation between diagnosis and prognosis of vector-borne diseases among dogs.Materials, Methods & Results: The material of this study was 46 dogs (36 were naturally infected with vector-borne diseases and 10 were healthy) from different breed, age and of both sexes. Venous blood samples were obtained to detect PLT counts, antibodies of ehrlichiosis, anaplasmosis, borreliosis, leishmaniosis and antigens of Dirofilaria immitis. The diagnosis of vector-borne diseases was performed by using a commercial ELISA assay kits. PLT count was performed with an automated blood cell counter analyser. In addition, PT, APTT and FIB concentrations were measured using a microcoagulometer. D-dimer concentrations were determined using fluorescence immunoassay rapid qu

An investigation of the Feline Immunodeficiency Virus (FIV) and Feline Leukemia Virus (FeLV) infections in cats in western Turkey / An investigation of the Feline Immunodeficiency Virus (FIV) and Feline Leukemia Virus (FeLV) infections in cats in western Turkey

Background: Feline Leukemia Virus (FeLV) and Feline Immunodeficiency Virus (FIV) are among the most important pathogens of cats. Despite being common world-wide, data on the prevalence of these viruses in western Turkey are very limited in the literature. The objective of this study was to investigate the presence and the prevalence of the FIV and FeLV infections in the house and stray cats in the Aegean region of western Turkey. Effects of the risk factors such as age, gender, and lifestyle on the prevalence of the infections as well as the relationship between the general health status of the animals and infection rates were investigated. Materials, Methods & Results: Blood samples were taken from the house and stray cats brought to the clinics of the Faculty of Veterinary Medicine at the Adnan Menderes University or the private veterinary clinics in the provinces of Aydin and Izmir, Turkey, during the period of the study from May 2009 to June 2010. The serum samples were tested using commercially available Enzyme-Linked Immunosorbent Assay (ELISA) kits to detect p27 antigen of FeLV, neutralizing antibodies against the gp70 protein of the FeLV, and antibodies against p17 and p24 antigens of FIV. Two hundred and ten cats were tested for FeLV antigen and FIV-specific antibodies whereas 172 cats were tested for antibodies against FeLV. Overall positivity rates for the FeLV a

Background: Feline Leukemia Virus (FeLV) and Feline Immunodeficiency Virus (FIV) are among the most important pathogens of cats. Despite being common world-wide, data on the prevalence of these viruses in western Turkey are very limited in the literature. The objective of this study was to investigate the presence and the prevalence of the FIV and FeLV infections in the house and stray cats in the Aegean region of western Turkey. Effects of the risk factors such as age, gender, and lifestyle on the prevalence of the infections as well as the relationship between the general health status of the animals and infection rates were investigated. Materials, Methods & Results: Blood samples were taken from the house and stray cats brought to the clinics of the Faculty of Veterinary Medicine at the Adnan Menderes University or the private veterinary clinics in the provinces of Aydin and Izmir, Turkey, during the period of the study from May 2009 to June 2010. The serum samples were tested using commercially available Enzyme-Linked Immunosorbent Assay (ELISA) kits to detect p27 antigen of FeLV, neutralizing antibodies against the gp70 protein of the FeLV, and antibodies against p17 and p24 antigens of FIV. Two hundred and ten cats were tested for FeLV antigen and FIV-specific antibodies whereas 172 cats were tested for antibodies against FeLV. Overall positivity rates for the FeLV a

An investigation of the Feline Immunodeficiency Virus (FIV) and Feline Leukemia Virus (FELV) infections in cats in Western Turkey

Background: Feline Leukemia Virus (FeLV) and Feline Immunodefi ciency Virus (FIV) are among the most important pathogens of cats. Despite being common world-wide, data on the prevalence of these viruses in western Turkey are very limited in the literature. The objective of this study was to investigate the presence and the prevalence of the FIV and FeLV infections in the house and stray cats in the Aegean region of western Turkey. Effects of the risk factors such as age, gender, and lifestyle on the prevalence of the infections as well as the relationship between the general health status of the animals and infection rates were investigated. Materials, Methods & Results: Blood samples were taken from the house and stray cats brought to the clinics of the Faculty of Veterinary Medicine at the Adnan Menderes University or the private veterinary clinics in the provinces of Aydin and Izmir, Turkey, during the period of the study from May 2009 to June 2010. The serum samples were tested using commercially available Enzyme-Linked Immunosorbent Assay (ELISA) kits to detect p27 antigen of FeLV, neutralizing antibodies against the gp70 protein of the FeLV, and antibodies against p17 and p24 antigens of FIV. Two hundred and ten cats were tested for FeLV antigen and FIV-specific antibodies whereas 172 cats were tested for antibodies against FeLV. Overall positivity rates for the FeLV antigen, antibodies against FeLV, and antibodies against FIV were 7.6% (16/210), 58.1% (100/172), and 19.5% (41/210), respectively. Seropositivity rates for antibodies against FeLV and FIV changed significantly from one province to another (P < 0.05). Serositivity for the antibodies against FIV were higher in male than the female animals (P < 0.05) and in house than the stray cats (P < 0.001). Animals with clinical symptoms when brought to the clinic had significantly higher FeLV antigen and the antibody titers against FIV than the apparently healthy animals (P < 0.001). Seropositivity for antibodies against FIV but not the rates of positivity for FeLV antigen and antibodies against FeLV were influenced by the age of the animal. Discussion: The results obtained in this study suggested that the FeLV and FIV infections were relatively common in western Turkey. The statistically signifi cant risk factors for the FIV infection included the province of residence, gender, life style, health status and age. Since prevalence of the FIV infection may significantly vary among Turkey's different geographical regions, prevalence studies that maybe important in the combat of the infections should be carried out independently in each province. Only province of residence and health status were risk for factors for the FeLV infections. Antibodies against FIV were more prevalent in the cats that were male, older than three years of age, lived in houses, and had clinical symptoms when brought to the clinics. The animals that presented with clinical symptoms when brought to the clinic had higher rates of positivity for FeLV antigen and FIV-specific antibodies (P < 0.01). These results suggest that sick animals are at higher risk for infection with these viruses and that the viruses may be involved in the aetiology of a variety of diseases. Analysis of the clinical findings, test results and reports in the literature suggest that these infections may present with various clinical symptoms and should be taken into careful consideration for differential diagnosis of animals in the clinic.

An investigation of the Feline Immunodeficiency Virus (FIV) and Feline Leukemia Virus (FeLV) infections in cats in western Turkey / An investigation of the Feline Immunodeficiency Virus (FIV) and Feline Leukemia Virus (FeLV) infections in cats in western Turkey

Background: Feline Leukemia Virus (FeLV) and Feline Immunodeficiency Virus (FIV) are among the most important pathogens of cats. Despite being common world-wide, data on the prevalence of these viruses in western Turkey are very limited in the literature. The objective of this study was to investigate the presence and the prevalence of the FIV and FeLV infections in the house and stray cats in the Aegean region of western Turkey. Effects of the risk factors such as age, gender, and lifestyle on the prevalence of the infections as well as the relationship between the general health status of the animals and infection rates were investigated. Materials, Methods & Results: Blood samples were taken from the house and stray cats brought to the clinics of the Faculty of Veterinary Medicine at the Adnan Menderes University or the private veterinary clinics in the provinces of Aydin and Izmir, Turkey, during the period of the study from May 2009 to June 2010. The serum samples were tested using commercially available Enzyme-Linked Immunosorbent Assay (ELISA) kits to detect p27 antigen of FeLV, neutralizing antibodies against the gp70 protein of the FeLV, and antibodies against p17 and p24 antigens of FIV. Two hundred and ten cats were tested for FeLV antigen and FIV-specific antibodies whereas 172 cats were tested for antibodies against FeLV. Overall positivity rates for the FeLV a

Background: Feline Leukemia Virus (FeLV) and Feline Immunodeficiency Virus (FIV) are among the most important pathogens of cats. Despite being common world-wide, data on the prevalence of these viruses in western Turkey are very limited in the literature. The objective of this study was to investigate the presence and the prevalence of the FIV and FeLV infections in the house and stray cats in the Aegean region of western Turkey. Effects of the risk factors such as age, gender, and lifestyle on the prevalence of the infections as well as the relationship between the general health status of the animals and infection rates were investigated. Materials, Methods & Results: Blood samples were taken from the house and stray cats brought to the clinics of the Faculty of Veterinary Medicine at the Adnan Menderes University or the private veterinary clinics in the provinces of Aydin and Izmir, Turkey, during the period of the study from May 2009 to June 2010. The serum samples were tested using commercially available Enzyme-Linked Immunosorbent Assay (ELISA) kits to detect p27 antigen of FeLV, neutralizing antibodies against the gp70 protein of the FeLV, and antibodies against p17 and p24 antigens of FIV. Two hundred and ten cats were tested for FeLV antigen and FIV-specific antibodies whereas 172 cats were tested for antibodies against FeLV. Overall positivity rates for the FeLV a

Interpretation of Coagulation Tendency Contributing to Thrombosis in Vector-Borne Diseases (Ehrlichiosis, Anaplasmosis, Leishmaniosis, and Dirofilariasis) among Dogs

Background: Vector-borne infectious and zoonotic diseases are an important health problem that directly affects human and animal health negatively. Results through evaluation of coagulation disorders among vector-borne diseases should be of beneficial for both human and dogs studies. According to the present authors knowledge reports regarding changes in platelet (PLT) count, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and D-dimer levels in dogs naturally infected with one or more vector-borne pathogens are lacking. Therefore, the present study was aimed to detecting those parameters for relation between diagnosis and prognosis of vector-borne diseases among dogs.Materials, Methods & Results: The material of this study was 46 dogs (36 were naturally infected with vector-borne diseases and 10 were healthy) from different breed, age and of both sexes. Venous blood samples were obtained to detect PLT counts, antibodies of ehrlichiosis, anaplasmosis, borreliosis, leishmaniosis and antigens of Dirofilaria immitis. The diagnosis of vector-borne diseases was performed by using a commercial ELISA assay kits. PLT count was performed with an automated blood cell counter analyser. In addition, PT, APTT and FIB concentrations were measured using a microcoagulometer. D-dimer concentrations were determined using fluorescence immunoassay rapid qu

Interpretation of Coagulation Tendency Contributing to Thrombosis in Vector-Borne Diseases (Ehrlichiosis, Anaplasmosis, Leishmaniosis, and Dirofilariasis) among Dogs

Background: Vector-borne infectious and zoonotic diseases are an important health problem that directly affects human and animal health negatively. Results through evaluation of coagulation disorders among vector-borne diseases should be of beneficial for both human and dogs studies. According to the present authors knowledge reports regarding changes in platelet (PLT) count, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and D-dimer levels in dogs naturally infected with one or more vector-borne pathogens are lacking. Therefore, the present study was aimed to detecting those parameters for relation between diagnosis and prognosis of vector-borne diseases among dogs.Materials, Methods & Results: The material of this study was 46 dogs (36 were naturally infected with vector-borne diseases and 10 were healthy) from different breed, age and of both sexes. Venous blood samples were obtained to detect PLT counts, antibodies of ehrlichiosis, anaplasmosis, borreliosis, leishmaniosis and antigens of Dirofilaria immitis. The diagnosis of vector-borne diseases was performed by using a commercial ELISA assay kits. PLT count was performed with an automated blood cell counter analyser. In addition, PT, APTT and FIB concentrations were measured using a microcoagulometer. D-dimer concentrations were determined using fluorescence immunoassay rapid qu

Interpretation of Coagulation Tendency Contributing to Thrombosis in Vector-Borne Diseases (Ehrlichiosis, Anaplasmosis, Leishmaniosis, and Dirofilariasis) among Dogs

Background: Vector-borne infectious and zoonotic diseases are an important health problem that directly affects human and animal health negatively. Results through evaluation of coagulation disorders among vector-borne diseases should be of beneficial for both human and dogs studies. According to the present authors knowledge reports regarding changes in platelet (PLT) count, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and D-dimer levels in dogs naturally infected with one or more vector-borne pathogens are lacking. Therefore, the present study was aimed to detecting those parameters for relation between diagnosis and prognosis of vector-borne diseases among dogs.Materials, Methods & Results: The material of this study was 46 dogs (36 were naturally infected with vector-borne diseases and 10 were healthy) from different breed, age and of both sexes. Venous blood samples were obtained to detect PLT counts, antibodies of ehrlichiosis, anaplasmosis, borreliosis, leishmaniosis and antigens of Dirofilaria immitis. The diagnosis of vector-borne diseases was performed by using a commercial ELISA assay kits. PLT count was performed with an automated blood cell counter analyser. In addition, PT, APTT and FIB concentrations were measured using a microcoagulometer. D-dimer concentrations were determined using fluorescence immunoassay rapid qu

Interpretation of Coagulation Tendency Contributing to Thrombosis in Vector-Borne Diseases (Ehrlichiosis, Anaplasmosis, Leishmaniosis, and Dirofilariasis) among Dogs

Background: Vector-borne infectious and zoonotic diseases are an important health problem that directly affects human and animal health negatively. Results through evaluation of coagulation disorders among vector-borne diseases should be of beneficial for both human and dogs studies. According to the present authors knowledge reports regarding changes in platelet (PLT) count, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and D-dimer levels in dogs naturally infected with one or more vector-borne pathogens are lacking. Therefore, the present study was aimed to detecting those parameters for relation between diagnosis and prognosis of vector-borne diseases among dogs.Materials, Methods & Results: The material of this study was 46 dogs (36 were naturally infected with vector-borne diseases and 10 were healthy) from different breed, age and of both sexes. Venous blood samples were obtained to detect PLT counts, antibodies of ehrlichiosis, anaplasmosis, borreliosis, leishmaniosis and antigens of Dirofilaria immitis. The diagnosis of vector-borne diseases was performed by using a commercial ELISA assay kits. PLT count was performed with an automated blood cell counter analyser. In addition, PT, APTT and FIB concentrations were measured using a microcoagulometer. D-dimer concentrations were determined using fluorescence immunoassay rapid qu

Interpretation of Coagulation Tendency Contributing to Thrombosis in Vector-Borne Diseases (Ehrlichiosis, Anaplasmosis, Leishmaniosis, and Dirofilariasis) among Dogs

Background: Vector-borne infectious and zoonotic diseases are an important health problem that directly affects human and animal health negatively. Results through evaluation of coagulation disorders among vector-borne diseases should be of beneficial for both human and dogs studies. According to the present authors knowledge reports regarding changes in platelet (PLT) count, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) and D-dimer levels in dogs naturally infected with one or more vector-borne pathogens are lacking. Therefore, the present study was aimed to detecting those parameters for relation between diagnosis and prognosis of vector-borne diseases among dogs.Materials, Methods & Results: The material of this study was 46 dogs (36 were naturally infected with vector-borne diseases and 10 were healthy) from different breed, age and of both sexes. Venous blood samples were obtained to detect PLT counts, antibodies of ehrlichiosis, anaplasmosis, borreliosis, leishmaniosis and antigens of Dirofilaria immitis. The diagnosis of vector-borne diseases was performed by using a commercial ELISA assay kits. PLT count was performed with an automated blood cell counter analyser. In addition, PT, APTT and FIB concentrations were measured using a microcoagulometer. D-dimer concentrations were determined using fluorescence immunoassay rapid qu