Resumo
Toxoplasmosis is a zoonosis caused by Toxoplasma gondii, a coccidian protozoan of worldwide distribution. The seroprevalence in canine population can be an alternative for measuring T. gondii urban spreading. A total of 780 blood samples from dogs were collected, during the yearly anti-rabies campaign, carried out by the Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Husbandry (FMVZ), São Paulo State University, UNESP, together with the county health authorities, in August 1999. Using Indirect Fluorescent Antibody Test (IFAT) for detecting antibodies anti-T. gondii in the sera samples, we observed that 258 dogs (33.1%) were positive. The associations between the serological results and the epidemiological variables were studied. Statistically significant differences were not found regarding sex (32.2% male and 34.3% female reactors). Dogs without a defined breed showed seropositivity statistically higher than the pedigreed group. The occurrence of infection was considered higher with age.
Resumo
The interrelation between thyroid gland and clinical changes was studied in adult intact cats kept under hyperthyroid state for 42 days. Parameters measured were red blood cell count (RBC), haemoglobin concentration, haematocrit, MCV, MCHC, total leukocytes (WBC) and differential leukocyte count. These characteristics were correlated with free and total T4 and total T3 serum concentrations. Excessive circulant thyroid hormones led to increased RBC, haematocrit, MCV, WBC, neutrophils, lymphocytes, eosinophils and monocytes in the studied cats. There were negative correlation between RBC and total T4 at the first weeks but positive correlation at the end of the experimental period. Leukocytes demonstrated negative correlation with free and total T4 levels. KEY-WORDS: Feline. Complete blood count. Hyperthyroidism.
A relação da glândula tireóide com valores hematológicos foi avaliada em gatos adultos, intactos e mantidos em estado hipertireóideo por um período de 42 dias. Os parâmetros estudados foram contagem total de hemácias, concentração de hemoglobina, hematócrito, concentração de hemoglobina corpuscular média, volume corpuscular médio, leucócitos totais e o diferencial e suas associações . Foram correlacionadas as variáveis com os níveis de tiroxina total (TT4), tiroxina livre (LT4) e triiodotironina total (TT3). O aumento dos níveis séricos dos hormônios tireoidianos provocou aumento de hemácias, hematócrito, hemoglobina, leucócitos, dos neutrófilos, linfócitos, eosinófilos e monócitos nos gatos. A contagem total de hemácias em relação à TT4 apresentou correlação negativa nos momentos iniciais e positiva nos finais. Os leucócitos apresentaram correlação negativa com a TT4 e LT4.PALAVRAS-CHAVE: Felino. Hemograma. Hipertireoidismo. Tireotoxicose.
Resumo
The interrelation between thyroid gland and clinical changes was studied in adult intact cats kept under hyperthyroid state for 42 days. Parameters measured were red blood cell count (RBC), haemoglobin concentration, haematocrit, MCV, MCHC, total leukocytes (WBC) and differential leukocyte count. These characteristics were correlated with free and total T4 and total T3 serum concentrations. Excessive circulant thyroid hormones led to increased RBC, haematocrit, MCV, WBC, neutrophils, lymphocytes, eosinophils and monocytes in the studied cats. There were negative correlation between RBC and total T4 at the first weeks but positive correlation at the end of the experimental period. Leukocytes demonstrated negative correlation with free and total T4 levels. KEY-WORDS: Feline. Complete blood count. Hyperthyroidism.
A relação da glândula tireóide com valores hematológicos foi avaliada em gatos adultos, intactos e mantidos em estado hipertireóideo por um período de 42 dias. Os parâmetros estudados foram contagem total de hemácias, concentração de hemoglobina, hematócrito, concentração de hemoglobina corpuscular média, volume corpuscular médio, leucócitos totais e o diferencial e suas associações . Foram correlacionadas as variáveis com os níveis de tiroxina total (TT4), tiroxina livre (LT4) e triiodotironina total (TT3). O aumento dos níveis séricos dos hormônios tireoidianos provocou aumento de hemácias, hematócrito, hemoglobina, leucócitos, dos neutrófilos, linfócitos, eosinófilos e monócitos nos gatos. A contagem total de hemácias em relação à TT4 apresentou correlação negativa nos momentos iniciais e positiva nos finais. Os leucócitos apresentaram correlação negativa com a TT4 e LT4.PALAVRAS-CHAVE: Felino. Hemograma. Hipertireoidismo. Tireotoxicose.