Resumo
Tissue fragments from 17 non-aborted and 93 aborted fetuses were histologically studied. No histological lesions were observed in non-aborted fetuses, and 51.6% of the aborted fetuses presented histological lesions. The main lesions were: focal gliosis and mononuclear infiltrate in liver, CNS, lungs and muscular tissues.(AU)
Assuntos
Animais , Feminino , Gravidez , Bovinos , Bovinos , Aborto AnimalResumo
The aim of this work was to determine ultrastructural changes on the intestinal mucosa and associated lymphoid tissues after an experimental infection with Cryptosporidium sp. Twelve piglets dosed orally with 1×10(6) oocysts were slaughtered on days 3, 6, 9 and 12 after inoculation. The ultrastructural lesions in the intestinal cells were irregular with thickened microvilli, cytoplasmic protrusions and vacuolation, swollen mitochondria, hypertrophic organelles and nuclei. The lymphocytes of the Peyers patches occasionally were mitotic with a larger number of lymphoblasts in the inoculated animals.
O presente estudo teve por objetivo investigar as alterações ultraestruturais da mucosa intestinal e do tecido linfóide associado na inoculação experimental de Cryptosporidium sp. Doze leitões foram inoculados experimentalmente por via oral com 1×10(6) oocistos e sacrificados 3, 6, 9 e 12 dias depois. Ao exame ultraestrutural de células intestinais observou-se espessamento e irregularidade de microvilosidades, citoplasma vacuolizado e com protrusões, edema mitocondrial, hipertrofia de organelas citoplasmáticas e do núcleo. Nas placas de Peyer observou-se ocasionalmente mitose de células linfóides, verificando-se maior número de células blásticas.