Eficácia de ivermectina e albendazol contra nematódeos gastrintestinais em rebanho ovino naturalmente infectado no município de Palmas-TO, Brasil

Objetivou-se avaliar a eficácia anti-helmíntica de ivermectina e albendazol em ovinos naturalmente infectados do município de Palmas/TO. Foram utilizados 24 animais, divididos em três grupos: não tratado (controle), tratado com ivermectina 1% e tratado com albendazol 1,9%. Realizou-se avaliação pré-tratamento (controle) e pós-tratamento (7º, 14º e 21º dia) e, após contagem de ovos por grama de fezes, foi calculado o percentual de redução (RCOF). Observou-se que ovinos tratados com albendazol apresentaram redução significativa de RCOF (81,92%) a partir do 7º dia pós-tratamento, chegando a 100% de redução com 21 dias. Já no grupo tratado com ivermectina, o controle começa a ser efetivo somente com 14 dias (49,81%), porém também com redução de 100% no 21º dia. Conclui-se, portanto, que ambos os fármacos testados são eficazes para controle de helmintos na propriedade estudada, não sugerindo ocorrência de resistência parasitária neste município. (AU)

The objective was to evaluate the anthelmintic effectiveness of ivermectin and albendazole in naturally infected sheep in Palmas/TO. 24 animals were divided into three groups: untreated (control), treated with 1% ivermectin and treated with 1,9% albendazole. It was made an evaluation pretreatment (control) and post-treatment (7, 14 and 21 days) and after of the count of eggs per gram of feces, was calculated the percentage of reduction (RCOF). It was observed that sheep treated with albendazole showed a significant RCOF (81.92%) from the 7th day after treatment, reaching 100% of control at 21 days. Already, in the group treated with ivermectin, the control begins to be effective 14 days (49.81%), but also occurred a reduction of 100% in 21 days. We conclude, therefore, that both drugs tested are effective for the helminth control in the studied property, does not suggest the occurrence of parasitic resistance. (AU)

Eficácia de ivermectina e albendazol contra nematódeos gastrintestinais em rebanho ovino naturalmente infectado no município de Palmas-TO, Brasil

Objetivou-se avaliar a eficácia anti-helmíntica de ivermectina e albendazol em ovinos naturalmente infectados do município de Palmas/TO. Foram utilizados 24 animais, divididos em três grupos: não tratado (controle), tratado com ivermectina 1% e tratado com albendazol 1,9%. Realizou-se avaliação pré-tratamento (controle) e pós-tratamento (7º, 14º e 21º dia) e, após contagem de ovos por grama de fezes, foi calculado o percentual de redução (RCOF). Observou-se que ovinos tratados com albendazol apresentaram redução significativa de RCOF (81,92%) a partir do 7º dia pós-tratamento, chegando a 100% de redução com 21 dias. Já no grupo tratado com ivermectina, o controle começa a ser efetivo somente com 14 dias (49,81%), porém também com redução de 100% no 21º dia. Conclui-se, portanto, que ambos os fármacos testados são eficazes para controle de helmintos na propriedade estudada, não sugerindo ocorrência de resistência parasitária neste município.

The objective was to evaluate the anthelmintic effectiveness of ivermectin and albendazole in naturally infected sheep in Palmas/TO. 24 animals were divided into three groups: untreated (control), treated with 1% ivermectin and treated with 1,9% albendazole. It was made an evaluation pretreatment (control) and post-treatment (7, 14 and 21 days) and after of the count of eggs per gram of feces, was calculated the percentage of reduction (RCOF). It was observed that sheep treated with albendazole showed a significant RCOF (81.92%) from the 7th day after treatment, reaching 100% of control at 21 days. Already, in the group treated with ivermectin, the control begins to be effective 14 days (49.81%), but also occurred a reduction of 100% in 21 days. We conclude, therefore, that both drugs tested are effective for the helminth control in the studied property, does not suggest the occurrence of parasitic resistance.

Renal dysplasia in dogs: retrospective study (2008-2013) / Displasia renal em cães: estudo retrospectivo (2008-2013)

Background: Renal dysplasia, which has been reported in some dogs and human patients, refers to a developmental disorder of renal parenchyma due to imperfect inductive interaction between the mesonephric duct and the metanephric blastemal. In dogs, the characteristic histological findings on which diagnosis is based include (1) persistent metanephric ducts surrounded by primitive mesenchyme, (2) fetal or immature glomeruli, (3) fetal or immature tubules, and (4) anomalous presence of interstitial fibrous tissue. The aim of this study was to report the major pathological and immunohistochemical features of nine young dogs necropsied with renal dysplasia.Cases: The necropsy files from the Laboratório de Patologia Veterinária (LPV) of the Universidade Federal do Mato Grosso (UFMT) were reviewed between the years 2008 and 2013. Dogs diagnosed with chronic kidney failure and macroscopic and histopathological renal lesions consistent with renal dysplasia were selected. Kidney fragments in paraffin blocks were cut and stained with hematoxylin and eosin and by immunohistochemistry (IHC) using anti-vimentin and anti-cytokeratin monoclonal antibodies. The staining was considered positive for the presence of at least one renal cell marked with brown cytoplasmic staining clear and unambiguous. A total of 787 necropsies of dogs were performed. Of these, 64 had a clinical diagnosis of [...]

Renal dysplasia in dogs: retrospective study (2008-2013) / Displasia renal em cães: estudo retrospectivo (2008-2013)

Background: Renal dysplasia, which has been reported in some dogs and human patients, refers to a developmental disorder of renal parenchyma due to imperfect inductive interaction between the mesonephric duct and the metanephric blastemal. In dogs, the characteristic histological findings on which diagnosis is based include (1) persistent metanephric ducts surrounded by primitive mesenchyme, (2) fetal or immature glomeruli, (3) fetal or immature tubules, and (4) anomalous presence of interstitial fibrous tissue. The aim of this study was to report the major pathological and immunohistochemical features of nine young dogs necropsied with renal dysplasia.Cases: The necropsy files from the Laboratório de Patologia Veterinária (LPV) of the Universidade Federal do Mato Grosso (UFMT) were reviewed between the years 2008 and 2013. Dogs diagnosed with chronic kidney failure and macroscopic and histopathological renal lesions consistent with renal dysplasia were selected. Kidney fragments in paraffin blocks were cut and stained with hematoxylin and eosin and by immunohistochemistry (IHC) using anti-vimentin and anti-cytokeratin monoclonal antibodies. The staining was considered positive for the presence of at least one renal cell marked with brown cytoplasmic staining clear and unambiguous. A total of 787 necropsies of dogs were performed. Of these, 64 had a clinical diagnosis of [...](AU)

Hemangiosarcoma in a free-living Rufous-bellied Thrush (Turdus rufiventris)

Background: Hemangiosarcoma is a malignant endothelial cell-derived neoplasm characterized by an intense cellular proliferation organized in a solid or cavernous pattern. Is characterized by intense cell proliferation, and organized in vascular slits, filled with blood, with fast grow and there is a high recurrence rate. This paper reports a case of multiple hemangiosarcoma in a Rufous-bellied Thrush (Turdus rufiventris). Case: A free-living Rufous-bellied Thrush (Turdus rufiventris), was attended at the veterinary hospital of the Federal University of Mato Grosso (UFMT) - Cuiabá, presenting prostration and three masses located in the following regions: left periorbital area, left lateral insertion of the beak and distal portion of the left tibia. The masses were blackened colored with an irregular aspect, and the cut surface was multiple cavity, filled with a blackened gelatinous material. The animal died during the surgical procedure and was sent to necropsy. Additionally, special immunohistochemistry staining was used in the tumors sections, with primary anti-S-100, anti-Von Willebrand Factor, anti-desmin, anti-actin, anti-cytokeratin and anti-vimentin. The three masses have rounded shape, multilobuled surface, deep red to blackened color, with skin adhered base, and, when cut, blackened color with multiple cavities filled with red to blackened gelatinous material and [...]

Hemangiosarcoma in a free-living Rufous-bellied Thrush (Turdus rufiventris)

Background: Hemangiosarcoma is a malignant endothelial cell-derived neoplasm characterized by an intense cellular proliferation organized in a solid or cavernous pattern. Is characterized by intense cell proliferation, and organized in vascular slits, filled with blood, with fast grow and there is a high recurrence rate. This paper reports a case of multiple hemangiosarcoma in a Rufous-bellied Thrush (Turdus rufiventris). Case: A free-living Rufous-bellied Thrush (Turdus rufiventris), was attended at the veterinary hospital of the Federal University of Mato Grosso (UFMT) - Cuiabá, presenting prostration and three masses located in the following regions: left periorbital area, left lateral insertion of the beak and distal portion of the left tibia. The masses were blackened colored with an irregular aspect, and the cut surface was multiple cavity, filled with a blackened gelatinous material. The animal died during the surgical procedure and was sent to necropsy. Additionally, special immunohistochemistry staining was used in the tumors sections, with primary anti-S-100, anti-Von Willebrand Factor, anti-desmin, anti-actin, anti-cytokeratin and anti-vimentin. The three masses have rounded shape, multilobuled surface, deep red to blackened color, with skin adhered base, and, when cut, blackened color with multiple cavities filled with red to blackened gelatinous material and [...](AU)