Cerebral vascular hamartoma in a Campeiro Bulldog

Background: Vascular hamartomas (VH) are rare or simply underdiagnosed injuries in veterinary medicine and represent a non-neoplastic developmental anomaly disorganization and proliferation of endothelial tissue. VH occur in any region of the body, however in the brain present clinical relevance related with the potential for spontaneous bleeding, adjacent tissue compression and convulsive activity. The aim of these reports is to describe clinical, pathological and immunohistochemical features of a case of cerebrovascular hamartoma and highlight the diagnosis of these rare brain disorder in dogs. Case: A 10-year-old male dog, a Campeiro Bulldog breed presented convulsions episodes and died before an elective surgical procedure for eyelid nodule removal. Three red nodules were observed in the brain, one between the parietal lobe and the left occipital lobe (in the medium suprasylviam sulcus), the other in the caudal region of the corpus callosum and the third one in the cerebellar cortex. Central nervous system, eyelids and most organs and tissues samples were collected, fixed in 10% formaldehyde and processed for histopathological analysis. Histologically, in the eyelid was detected a sebaceous adenoma. The nervous system samples revealed well-differentiated sizes vascular structures with thin-walled and blood-filled, promoting compression of the brain. Normal neuropile was detected between the vascular structures substantiating cerebral vascular hamartoma diagnosis in the dog. Immunohistochemical assay was conducted with CD31 (monoclonal mouse antibody anti-CD31, Clone JC70A, Dako Corp.) and Von Willebrand factor (monoclonal mouse antibody anti-Von Willebrand factor, Clone F8/86, Dako Corp.) using the biotin–peroxidase–streptavidin method (PolyDetector Plus DAB–HRP, Bio SB) on CNS sections to confirm the vascular origin of the lining cells in the mass….

Cerebral vascular hamartoma in a Campeiro Bulldog

Background: Vascular hamartomas (VH) are rare or simply underdiagnosed injuries in veterinary medicine and represent a non-neoplastic developmental anomaly disorganization and proliferation of endothelial tissue. VH occur in any region of the body, however in the brain present clinical relevance related with the potential for spontaneous bleeding, adjacent tissue compression and convulsive activity. The aim of these reports is to describe clinical, pathological and immunohistochemical features of a case of cerebrovascular hamartoma and highlight the diagnosis of these rare brain disorder in dogs. Case: A 10-year-old male dog, a Campeiro Bulldog breed presented convulsions episodes and died before an elective surgical procedure for eyelid nodule removal. Three red nodules were observed in the brain, one between the parietal lobe and the left occipital lobe (in the medium suprasylviam sulcus), the other in the caudal region of the corpus callosum and the third one in the cerebellar cortex. Central nervous system, eyelids and most organs and tissues samples were collected, fixed in 10% formaldehyde and processed for histopathological analysis. Histologically, in the eyelid was detected a sebaceous adenoma. The nervous system samples revealed well-differentiated sizes vascular structures with thin-walled and blood-filled, promoting compression of the brain. Normal neuropile was detected between the vascular structures substantiating cerebral vascular hamartoma diagnosis in the dog. Immunohistochemical assay was conducted with CD31 (monoclonal mouse antibody anti-CD31, Clone JC70A, Dako Corp.) and Von Willebrand factor (monoclonal mouse antibody anti-Von Willebrand factor, Clone F8/86, Dako Corp.) using the biotin–peroxidase–streptavidin method (PolyDetector Plus DAB–HRP, Bio SB) on CNS sections to confirm the vascular origin of the lining cells in the mass….(AU)

Intoxicação espontânea por antibióticos ionóforos em equinos no Distrito Federal / Spontaneous intoxication by ionophortic antibiotics in equine on Distrito Federal

Quinze equinos em um haras na cidade satélite de Brazlândia-DF foram atendidos apresentando sinais clínicos caracterizados por quadro álgico abdominal, distúrbios locomotores, incoordenação e decúbito, após histórico de ingestão de um novo lote de ração. Três animais tiveram piora clínica e morreram. Os achados de necropsia consistiam em lesões em musculatura esquelética e miocárdio. O exame histológico revelou miopatia degenerativa, necrose segmentar e flocular. Correlacionando a etiopatogenia, sinais clínicos, achados necroscópicos e histopatológicos concluímos a possibilidade de surto por intoxicação de antiobióticos ionofóros.

Fifteen equines in a farm in the satellite city of Brazlândia/DF were treated with clinical signs characterized by abdominal pain, locomotor disorders, incoordination and decubitus, after a history of ingestion of a new feed batch. Three animals had clinical worsening and died. The necropsy findings consisted of skeletal muscle and myocardial lesions. Histological examination revealed degenerative myopathy, segmental and flocular necrosis. Correlating the etiopathogenesis, clinical signs, necroscopic and histopathological findings we conclude the possibility of an outbreakof intoxication of ionophore antiobiotics.

Intoxicação espontânea por antibióticos ionóforos em equinos no Distrito Federal / Spontaneous intoxication by ionophortic antibiotics in equine on Distrito Federal

Quinze equinos em um haras na cidade satélite de Brazlândia-DF foram atendidos apresentando sinais clínicos caracterizados por quadro álgico abdominal, distúrbios locomotores, incoordenação e decúbito, após histórico de ingestão de um novo lote de ração. Três animais tiveram piora clínica e morreram. Os achados de necropsia consistiam em lesões em musculatura esquelética e miocárdio. O exame histológico revelou miopatia degenerativa, necrose segmentar e flocular. Correlacionando a etiopatogenia, sinais clínicos, achados necroscópicos e histopatológicos concluímos a possibilidade de surto por intoxicação de antiobióticos ionofóros.(AU)

Fifteen equines in a farm in the satellite city of Brazlândia/DF were treated with clinical signs characterized by abdominal pain, locomotor disorders, incoordination and decubitus, after a history of ingestion of a new feed batch. Three animals had clinical worsening and died. The necropsy findings consisted of skeletal muscle and myocardial lesions. Histological examination revealed degenerative myopathy, segmental and flocular necrosis. Correlating the etiopathogenesis, clinical signs, necroscopic and histopathological findings we conclude the possibility of an outbreakof intoxication of ionophore antiobiotics.(AU)

Principais doenças em Anseriformes / Major diseases in Anseriforme

Anseriforme é uma ordem composta por inúmeras espécies de aves aquáticas. No Brasil as principais espécies criadas são patos e gansos em sua maioria criadas em sistemas de subsistência, poucos são os criatórios industriais. Mesmo com a produção informal o comércio de aves vivas, ovos e carne é pratica comum em todo território nacional, mas não se tem conhecimento da prevalência de enfermidades em aves aquáticas, podendo trazer risco a saúde pública. Anseriformes podem apresentar tanto doença clínica quanto inaparente, de etiologia viral, bacteriana, parasitária e micótica. Estudos sobre quadro clínico, aspectos epidemiológicos, achados anatomopatológicos são necessários para criar métodos diagnósticos eficazes para identificar aves doentes. Doenças virais são as mais relatadas e de maior impacto econômico em criações dessa ordem de aves, mais as enfermidades bacterianas, assim como micóticas e parasitárias também podem ocorrer. Por esse motivo, esse estudo tem como objetivo revisar as principais enfermidades presentes em aves aquáticas.

Anseriforme is an order composed of numerous species of waterfowl. In Brazil the mainspecies created are ducks and geese, mostly in sustenance systems, there are few industrial farms.Even with informal production trade in live poultry, eggs and meat is common practice throughoutthe country, but it isn’t aware of the prevalence of disease in waterfowl, may pose a risk to publichealth. Anseriformes can present both clinical disease and unapparent, viral diseases, bacterial,parasitic and fungal. Studies on clinical, epidemiological, pathological findings are needed to createeffective methods diagnostics to identify sick birds. Viral diseases are the most reported and greatereconomic impact in that order poultry farms, most bacterial diseases, as well as fungal and parasiticmay also occur. Therefore, this study aims to review the main diseases present in waterfowl.

Principais doenças em Anseriformes / Major diseases in Anseriforme

Anseriforme é uma ordem composta por inúmeras espécies de aves aquáticas. No Brasil as principais espécies criadas são patos e gansos em sua maioria criadas em sistemas de subsistência, poucos são os criatórios industriais. Mesmo com a produção informal o comércio de aves vivas, ovos e carne é pratica comum em todo território nacional, mas não se tem conhecimento da prevalência de enfermidades em aves aquáticas, podendo trazer risco a saúde pública. Anseriformes podem apresentar tanto doença clínica quanto inaparente, de etiologia viral, bacteriana, parasitária e micótica. Estudos sobre quadro clínico, aspectos epidemiológicos, achados anatomopatológicos são necessários para criar métodos diagnósticos eficazes para identificar aves doentes. Doenças virais são as mais relatadas e de maior impacto econômico em criações dessa ordem de aves, mais as enfermidades bacterianas, assim como micóticas e parasitárias também podem ocorrer. Por esse motivo, esse estudo tem como objetivo revisar as principais enfermidades presentes em aves aquáticas.(AU)

Anseriforme is an order composed of numerous species of waterfowl. In Brazil the mainspecies created are ducks and geese, mostly in sustenance systems, there are few industrial farms.Even with informal production trade in live poultry, eggs and meat is common practice throughoutthe country, but it isnt aware of the prevalence of disease in waterfowl, may pose a risk to publichealth. Anseriformes can present both clinical disease and unapparent, viral diseases, bacterial,parasitic and fungal. Studies on clinical, epidemiological, pathological findings are needed to createeffective methods diagnostics to identify sick birds. Viral diseases are the most reported and greatereconomic impact in that order poultry farms, most bacterial diseases, as well as fungal and parasiticmay also occur. Therefore, this study aims to review the main diseases present in waterfowl.(AU)