Canine oral osteocartilaginous malignant amelanotic melanoma with pulmonary metastasis

Background: Melanomas are typically malignant neoplasms commonly observed in the oral cavity of dogs. The classical presentation of melanomas with characteristic melanin pigmentation is easy to diagnose; however, in some cases, the lack of melanin production in the amelanotic oral tumors cause a delay in establishing the precocious diagnosis and consequent treatment. The aim of this report was to evaluate the histopathological and immunohistochemical aspects of an oral amelanotic melanoma with osteocartilaginous formation and metastasis in a dog, in a temporal way.Case: A 10-year-old male German Shepherd dog, presenting mouth bleeding with an amelanotic melanoma located between the upper incisors was received at the Veterinary Hospital of the Catholic University Dom Bosco (UCDB), Campo Grande, MS, Brazil. The animal was clinically evaluated and radiography was performed. The tumor was surgically removed and a sample was collected for histopathological examination that revealed spindloid and some epithelioid morphological cell types surrounded by a fibromatous matrix with moderate amounts of fibrovascular stroma. Approximately 1 month after surgical removal, recovery of the tumor was observed, and a second clinical analysis and collection of sample were performed. These procedures were repeated three times showing the same histopathological characteristics added by myxoid, chondroid, fibromatous tissue, and small groups of chondrocytes as well as central areas of irregular mineralized spicules. X-ray examination revealed proliferative and lytic bone infiltration in the jaw. Immunohistochemical analysis for melanocytic differentiation markers was performed showing positivity to Melan-A, tyrosinase and HMB-45 immunoreactivity, while no S100 reactivity was detected. After 11 months of the first biopsy, pleural effusion and radiopaque disseminated nodules of 1cm in the lungs were detected by X-ray. The animal died and necropsy was conducted.[...](AU)

Canine oral osteocartilaginous malignant amelanotic melanoma with pulmonary metastasis

Background: Melanomas are typically malignant neoplasms commonly observed in the oral cavity of dogs. The classical presentation of melanomas with characteristic melanin pigmentation is easy to diagnose; however, in some cases, the lack of melanin production in the amelanotic oral tumors cause a delay in establishing the precocious diagnosis and consequent treatment. The aim of this report was to evaluate the histopathological and immunohistochemical aspects of an oral amelanotic melanoma with osteocartilaginous formation and metastasis in a dog, in a temporal way.Case: A 10-year-old male German Shepherd dog, presenting mouth bleeding with an amelanotic melanoma located between the upper incisors was received at the Veterinary Hospital of the Catholic University Dom Bosco (UCDB), Campo Grande, MS, Brazil. The animal was clinically evaluated and radiography was performed. The tumor was surgically removed and a sample was collected for histopathological examination that revealed spindloid and some epithelioid morphological cell types surrounded by a fibromatous matrix with moderate amounts of fibrovascular stroma. Approximately 1 month after surgical removal, recovery of the tumor was observed, and a second clinical analysis and collection of sample were performed. These procedures were repeated three times showing the same histopathological characteristics added by myxoid, chondroid, fibromatous tissue, and small groups of chondrocytes as well as central areas of irregular mineralized spicules. X-ray examination revealed proliferative and lytic bone infiltration in the jaw. Immunohistochemical analysis for melanocytic differentiation markers was performed showing positivity to Melan-A, tyrosinase and HMB-45 immunoreactivity, while no S100 reactivity was detected. After 11 months of the first biopsy, pleural effusion and radiopaque disseminated nodules of 1cm in the lungs were detected by X-ray. The animal died and necropsy was conducted.[...]

Prospective clinical assessment of tibial tuberosity advancement for the treatment of cranial cruciate ligament rupture in dogs

Purpose: To evaluate clinically dogs that underwent tibial tuberosity advancement (TTA) six months previously. Methods: Dogs of various breeds, gender, weight, and age that had CCL rupture and underwent TTA for treatment were included in this study. Parapatellar arthrotomy was performed in all patients to assess the joint for a ruptured ligament and meniscal injury before the TTA. The appropriate cage for the TTA was chosen with planning surgery. The surgical procedure was performed according to the literature, using a modified Maquet technique. Six months after surgery, lameness during walking; muscular atrophy; crepitation, cranial drawer and tibial compression tests and quality of life based on owners evaluation were assessed. Results: Postoperative complications were observed in only one knee (4.76%), with a surgical site seroma. The mean lameness score at walking was 0.29 (± 0.64). The mean score regarding muscular atrophy was 0.95 (± 1.56). The mean score of the cranial drawer test, in a range from 0 to 5, was 1.52 (± 1.54). The owners rated the dogs quality of life as excellent in 44%, good in 30%, and moderate in 17%. Conclusion: This clinical study supports the affirmation that patients who undergo TTA for treatment of CCL rupture have an acceptable response.(AU)

Adrenalectomia em cão para tratamento de Feocromocitoma maligno: relato de caso / Adrenalectomia in dog for treatment of Feochromocytoma maligno: case report / Adrenalectomía en perro para tratamiento de Feocromocitoma maligno: relato de caso

Foi atendida uma fêmea, canina, de raça Chow Chow, com oitos anos de idade com histórico de anorexia há dois dias. Apresentou ao exame físico pelo opaco, foi solicitado hemograma que apresentou anemia,hiperproteinemia e eosinofilia, foi realizado exame bioquímico ALT, FA, ureia e creatinina que não obtiveram alterações.Na ultrassonografia abdominal encontrou-se adenomegalia por hiperadrenocorticismo devido a neoplasia em glândula adrenal direita. Sendo indicado como tratamento adrenalectomia unilateral direita, no exame histopatológico foi caracterizado o Feocromocitoma maligno. O feocromocitoma maligno é um tumor característico de glândula adrenal, ocorre normalmente de forma unilateral. Os tumores adrenocorticais são responsáveis por 15 a 20% do hiperadrenocorticismo (HAC) espontâneo em cães, sendo mais comuns os adenomas e os carcinomas.(AU)

An eight-year-old female, canine Chow Chow breed with an anorexia history of two days old was seen.He was submitted to a physical examination for the opaque, he was asked for a blood count that presented anemia,hyperproteinemia and eosinophilia, a biochemical ALT, AF, urea and creatinine test were performed, which did not change. In abdominal ultrasonography adenomegaly was observed due to hyperadrenocorticism due to neoplasia in the right adrenal gland. Being indicated as a right unilateral adrenalectomy treatment, histopathological examination characterized the malignant pheochromocytoma.Malignant pheochromocytoma is a tumor characteristic of the adrenal gland, usually occurs unilaterally. Adrenocortical tumors account for 15 to 20% of spontaneous hyperadrenocorticism (HAC) in dogs, with adenomas and carcinomas being more common.(AU)

La edad de ocho años de edad, canina Chow Chow crianza con una anorexia historia de dos días de edad. En el caso de que se produzca una hemorragia, la hiperproteinemia y la eosinophilia, el bioquímico ALT, el AF, la urea y la creatinina test fueron realizadas, que no cambió. In abdominal ultrasonografía adenomegaly fue observado debido a hiperadrenocorticismo debido a la neoplasia en el derecho adrenal gland. El uso de las a la derecha unilateral adrenalectomy del tratamiento, el histopathological examina el maligno pheochromocytoma.Malignantpheochromocytoma es un tumor característico de la adrenal gland, generalmente ocurre unilateralmente.Adrenocortical tumors account para 15 a 20% de espontaneous hyperadrenocorticism (HAC) en perros, con adenomas y carcinomas ser más comunes.(AU)

Adrenalectomia em cão para tratamento de Feocromocitoma maligno: relato de caso / Adrenalectomia in dog for treatment of Feochromocytoma maligno: case report / Adrenalectomía en perro para tratamiento de Feocromocitoma maligno: relato de caso

Foi atendida uma fêmea, canina, de raça Chow Chow, com oitos anos de idade com histórico de anorexia há dois dias. Apresentou ao exame físico pelo opaco, foi solicitado hemograma que apresentou anemia,hiperproteinemia e eosinofilia, foi realizado exame bioquímico ALT, FA, ureia e creatinina que não obtiveram alterações.Na ultrassonografia abdominal encontrou-se adenomegalia por hiperadrenocorticismo devido a neoplasia em glândula adrenal direita. Sendo indicado como tratamento adrenalectomia unilateral direita, no exame histopatológico foi caracterizado o Feocromocitoma maligno. O feocromocitoma maligno é um tumor característico de glândula adrenal, ocorre normalmente de forma unilateral. Os tumores adrenocorticais são responsáveis por 15 a 20% do hiperadrenocorticismo (HAC) espontâneo em cães, sendo mais comuns os adenomas e os carcinomas.

An eight-year-old female, canine Chow Chow breed with an anorexia history of two days old was seen.He was submitted to a physical examination for the opaque, he was asked for a blood count that presented anemia,hyperproteinemia and eosinophilia, a biochemical ALT, AF, urea and creatinine test were performed, which did not change. In abdominal ultrasonography adenomegaly was observed due to hyperadrenocorticism due to neoplasia in the right adrenal gland. Being indicated as a right unilateral adrenalectomy treatment, histopathological examination characterized the malignant pheochromocytoma.Malignant pheochromocytoma is a tumor characteristic of the adrenal gland, usually occurs unilaterally. Adrenocortical tumors account for 15 to 20% of spontaneous hyperadrenocorticism (HAC) in dogs, with adenomas and carcinomas being more common.

La edad de ocho años de edad, canina Chow Chow crianza con una anorexia historia de dos días de edad. En el caso de que se produzca una hemorragia, la hiperproteinemia y la eosinophilia, el bioquímico ALT, el AF, la urea y la creatinina test fueron realizadas, que no cambió. In abdominal ultrasonografía adenomegaly fue observado debido a hiperadrenocorticismo debido a la neoplasia en el derecho adrenal gland. El uso de las a la derecha unilateral adrenalectomy del tratamiento, el histopathological examina el maligno pheochromocytoma.Malignantpheochromocytoma es un tumor característico de la adrenal gland, generalmente ocurre unilateralmente.Adrenocortical tumors account para 15 a 20% de espontaneous hyperadrenocorticism (HAC) en perros, con adenomas y carcinomas ser más comunes.

Estudo experimental e comparativo entre as técnicas de pino em cavilha com fio fluorcarbono monofilamentar e colocefalectomia para estabilização coxofemoral em cães

No presente trabalho comparou-se, experimentalmente, duas técnicas: a estabilização coxofemoral com pino em cavilha ou ?toggle pin? e a colocefalectomia. Foram utilizados 16 cães, machos ou fêmeas, distribuidos em dois grupos: o de Pino (GP) e o Colocefalectomia (GC), os quais foram separados em 4 subgrupos: animais com peso superior e, inferior ou igual a 15 kg. Avaliou-se o tempo de cirurgia, o grau de atrofia muscular, a deambulação e a dor, além de presença ou não de alterações radiograficas da articulação. O tempo cirúrgico, devido a maior complexidade da técnica do pino, foi menor no GC. A técnica do GP foi melhor quanto à recuperação do membro, apresentando menor atrofia muscular

On the present assay was compared experimentally between two techniques: hip joint stabilization with toggle pin and hip joint stabilization with head of the femur. Were used 16 dogs, female or male, distributed in 2 groups: the pin group (GP) and head of the femur group (GC), the groups were distributed in 4 subgroups: by weight equal, more or less than 15kg. Evaluating the time of surgery, and the notch of muscle atrophy, wander around the pain and also with the presence or not of alterations on the joint radiograph. The time of surgery is longer in the technique of pin than on the group GC, because the technique of pin had more complexity. So the technical of the group GP was better on the recovery member, which presented less muscle atrophy