Melanomas em cães no Sertão do Nordeste do Brasil - epidemiologia, fatores de risco e achados clinicopatológicos / Melanoma in dogs in the backlands of Northeastern Brazil - epidemiology, risk factors and clinicopathological findings

Background: Melanoma is a malignant neoplasm that arises from melanocytes and malanoblasts. It is also more frequently reported in dogs than in other species. They may arise from melanocytes in the skin, on the surfaces of the mucous membranes, and eyes. The aim of this study was to describe the epidemiological aspects, risk factors and clinicopathological findings of melanoma in dogs in the backlands, northeastern Brazil. Materials, Methods & Results: A retrospective study was carried out in all biopsy samples and necropsy examinations of dogs, from January 2003 to December 2021, at the Animal Pathology Laboratory of the Federal University of Campina Grande, Patos, Paraiba, northeastern Brazil. Epidemiological data, clinical signs, and gross lesions were reviewed from the diagnostic laboratory reports. Samples of the skin, lymph nodes, central nervous system and organs of the thoracic and abdominal cavities were fixed in 10% buffered formalin, processed routinely for histopathology, embedded in paraffin wax, cut into 4 µm sections, and stained with hematoxylin and eosin (HE). Histological sections were also submitted to immunohistochemistry with the primary antibody anti-Melan A. Of the 4717 records found, 1158 (24.5%) were diagnosed with neoplasms, of which 48 (4.14%) cases were of melanoma. Of this total, 28 (58.3%) dogs were elderly, 19 (39.6%) were adults, and 1 (2.1%) was young. Mixed breed animals were the most affected (42.6%), followed by the pinscher breed (19.1%). According to the anatomical region, the most affected site was the skin (38/53=71.7%), followed by the oral cavity (12/53=22.65%) and the eyes (3/53=5.7%). Grossly, the skin lesions were characterized by exophytic and usually blackened, sometimes irregular and firm, nodules. At cut, they had a smooth, compact and blackened surface. Lesions in the oral cavity were characterized by blackened, irregular and infiltrating nodules or masses. The ocular lesions were always unilateral and were characterized by an enlarged and diffusely blackened eyeball, with areas of ulceration and subversion of tissue architecture. In 5 animals there was more than one anatomical site affected, totaling 53 lesions. In 9 (17%) cases, metastases were identified, 8 in regional lymph nodes and 1 in the lung. Histopathology showed a densely non-encapsulated, poorly delimited, expansive and infiltrative neoplasm, composed of neoplastic cells arranged in islands or nests and supported by fibrovascular stroma, containing a variable amount of brownish pigment (melanin). Immunohistochemistry showed strong immunostaining of the neoplastic cells in brown by the anti-Melan A antibody. Discussion: The diagnosis of melanoma was established based on epidemiological, clinical, anatomopathological, and immunohistochemical findings. Gender is not a predisposing factor, and although there was no statistically significant relationship, males were more affected. Senescence is a conditioning risk factor. Elderly animals were more affected (P < 0.0001) than adult ones, with OR = 4.38; and young ones (P = 0.0051), with OR = 12.65. Some breeds, especially those with marked skin pigmentation, were more affected, however the most affected ones in this survey were pinscher and poodle. Cutaneous melanoma accounted for almost 72% of cases, contesting recent studies where oral cavity melanoma was more frequent. Therefore, it is believed that the climatic conditions of the backlands sub-region, in northeastern Brazil, associated with the individual characteristics of the dogs, are involved in the development of these neoplasms, since the climate is predominantly dry, with high temperatures throughout the year, with maximums that can reach 40ºC, favoring the exposure to high incidence of ultraviolet radiation.

Systemic coccidioidomycosis in a dog in Northeastern Brazil / Coccidioidomicose sistêmica em um cão no Nordeste do Brasil

We described a case of systemic infection by Coccidioides sp. in a dog. An adult, mixed breed, free-ranging male dog presented with clinical signs that included apathy, cachexia, anorexia, limited mobility with sternal recumbency, bilateral mucopurulent ocular discharge, dyspnoea, pulmonary crepitation, erosive and nodular lesions on the skin, and swelling and stiffness of the left tibiotarsal joint. The dog was submitted to a postmortem examination. Grossly, there were multiple yellow to white nodules in various organs. Histologically, the lesions were characterized as pyogranulomatous inflammation associated with fungal spherules morphologically consistent with Coccidioides sp. The dog was concomitantly diagnosed with undifferentiated sarcoma affecting the skin, lymph nodes, liver, and testicles. The diagnosis of coccidioidomycosis was made based on the histologic changes associated with morphotintorial features and positive immunolabeling of organisms with anti-Coccidioides immunohistochemistry. This case demonstrated that Coccidioides sp. can infect dogs that inhabit urban centers in the semiarid region of Northeastern Brazil, likely due to exposure to dust from contaminated environments.

Descreve-se um caso de infecção sistêmica por Coccidioides em um cão. Um cão adulto, sem raça definida e errante, atendido com sinais clínicos que incluíram apatia, caquexia, anorexia, dificuldade de locomoção com decúbito esternal, secreção ocular bilateral mucopurulenta, dispneia, crepitação pulmonar, lesões erosivas e nodulares na pele, aumento de volume e rigidez na articulação tibiotársica do membro pélvico esquerdo. O cão foi submetido a um exame post-mortem. Macroscopicamente, haviam múltiplos nódulos amarelo-brancacentos em vários órgãos. Histologicamente, as lesões foram caracterizadas por inflamação piogranulomatosa associada a esférulas fúngicas morfologicamente consistentes com Coccidioides sp. O cão foi diagnosticado concomitantemente com sarcoma indiferenciado afetando a pele, linfonodos, fígado e testículos. O diagnóstico de coccidioidomicose foi realizado com base nas alterações histológicas associadas as características morfotintoriais e imunomarcação positiva dos organismos com anti-Coccidioides na imuno-histoquímica. Esse caso demonstra que Coccidioides sp. pode infectar cães que habitam centros urbanos no semiárido do Nordeste do Brasil, provavelmente devido à exposição a poeira de ambientes contaminados.

Systemic coccidioidomycosis in a dog in Northeastern Brazil / Coccidioidomicose sistêmica em um cão no Nordeste do Brasil

ABSTRACT: We described a case of systemic infection by Coccidioides sp. in a dog. An adult, mixed breed, free-ranging male dog presented with clinical signs that included apathy, cachexia, anorexia, limited mobility with sternal recumbency, bilateral mucopurulent ocular discharge, dyspnoea, pulmonary crepitation, erosive and nodular lesions on the skin, and swelling and stiffness of the left tibiotarsal joint. The dog was submitted to a postmortem examination. Grossly, there were multiple yellow to white nodules in various organs. Histologically, the lesions were characterized as pyogranulomatous inflammation associated with fungal spherules morphologically consistent with Coccidioides sp. The dog was concomitantly diagnosed with undifferentiated sarcoma affecting the skin, lymph nodes, liver, and testicles. The diagnosis of coccidioidomycosis was made based on the histologic changes associated with morphotintorial features and positive immunolabeling of organisms with anti-Coccidioides immunohistochemistry. This case demonstrated that Coccidioides sp. can infect dogs that inhabit urban centers in the semiarid region of Northeastern Brazil, likely due to exposure to dust from contaminated environments.

RESUMO: Descreve-se um caso de infecção sistêmica por Coccidioides em um cão. Um cão adulto, sem raça definida e errante, atendido com sinais clínicos que incluíram apatia, caquexia, anorexia, dificuldade de locomoção com decúbito esternal, secreção ocular bilateral mucopurulenta, dispneia, crepitação pulmonar, lesões erosivas e nodulares na pele, aumento de volume e rigidez na articulação tibiotársica do membro pélvico esquerdo. O cão foi submetido a um exame post-mortem. Macroscopicamente, haviam múltiplos nódulos amarelo-brancacentos em vários órgãos. Histologicamente, as lesões foram caracterizadas por inflamação piogranulomatosa associada a esférulas fúngicas morfologicamente consistentes com Coccidioides sp. O cão foi diagnosticado concomitantemente com sarcoma indiferenciado afetando a pele, linfonodos, fígado e testículos. O diagnóstico de coccidioidomicose foi realizado com base nas alterações histológicas associadas as características morfotintoriais e imunomarcação positiva dos organismos com anti-Coccidioides na imuno-histoquímica. Esse caso demonstra que Coccidioides sp. pode infectar cães que habitam centros urbanos no semiárido do Nordeste do Brasil, provavelmente devido à exposição a poeira de ambientes contaminados.

Systemic coccidioidomycosis in a dog in Northeastern Brazil / Coccidioidomicose sistêmica em um cão no Nordeste do Brasil

We described a case of systemic infection by Coccidioides sp. in a dog. An adult, mixed breed, free-ranging male dog presented with clinical signs that included apathy, cachexia, anorexia, limited mobility with sternal recumbency, bilateral mucopurulent ocular discharge, dyspnoea, pulmonary crepitation, erosive and nodular lesions on the skin, and swelling and stiffness of the left tibiotarsal joint. The dog was submitted to a postmortem examination. Grossly, there were multiple yellow to white nodules in various organs. Histologically, the lesions were characterized as pyogranulomatous inflammation associated with fungal spherules morphologically consistent with Coccidioides sp. The dog was concomitantly diagnosed with undifferentiated sarcoma affecting the skin, lymph nodes, liver, and testicles. The diagnosis of coccidioidomycosis was made based on the histologic changes associated with morphotintorial features and positive immunolabeling of organisms with anti-Coccidioides immunohistochemistry. This case demonstrated that Coccidioides sp. can infect dogs that inhabit urban centers in the semiarid region of Northeastern Brazil, likely due to exposure to dust from contaminated environments.(AU)

Descreve-se um caso de infecção sistêmica por Coccidioides em um cão. Um cão adulto, sem raça definida e errante, atendido com sinais clínicos que incluíram apatia, caquexia, anorexia, dificuldade de locomoção com decúbito esternal, secreção ocular bilateral mucopurulenta, dispneia, crepitação pulmonar, lesões erosivas e nodulares na pele, aumento de volume e rigidez na articulação tibiotársica do membro pélvico esquerdo. O cão foi submetido a um exame post-mortem. Macroscopicamente, haviam múltiplos nódulos amarelo-brancacentos em vários órgãos. Histologicamente, as lesões foram caracterizadas por inflamação piogranulomatosa associada a esférulas fúngicas morfologicamente consistentes com Coccidioides sp. O cão foi diagnosticado concomitantemente com sarcoma indiferenciado afetando a pele, linfonodos, fígado e testículos. O diagnóstico de coccidioidomicose foi realizado com base nas alterações histológicas associadas as características morfotintoriais e imunomarcação positiva dos organismos com anti-Coccidioides na imuno-histoquímica. Esse caso demonstra que Coccidioides sp. pode infectar cães que habitam centros urbanos no semiárido do Nordeste do Brasil, provavelmente devido à exposição a poeira de ambientes contaminados.(AU)

Babesiose encefálica em cães: aspectos clínicos, epidemiológicos e patológicos / Encephalic babesiosis in dogs: clinical, epidemiological and pathological aspects

Background: Babesiosis is a hemolytic disease caused by protozoa of the genus Babesia spp. responsible for causinganemia, fever and splenomegaly in several animal species. The cerebral involvement of babesiosis in dogs manifests itselfin a hyperacute manner with neurological disorders such as motor incoordination, nystagmus, anisocoria and convulsions.In Brazil there still are no studies which describe the pathological aspects of cerebral babesiosis in dogs together withinformation relating to its clinical aspects and epidemiology. Therefore, this work had as an objective to describe sevencases of canine cerebral babesiosis, emphasizing its epidemiological, clinical and pathological aspects.Materials, Methods & Results: All the records of the necropsies performed in dogs at Animal Pathology Laboratory (LPA/HV) of the Federal University of Campina Grande (UFCG), Patos Campus, Paraíba, Northeast of Brazil were identified. In Theperiod from January 2003 to December 2017. Later, were selected all the cases of cerebral babesiosis. Were included in thestudy the cases in which was possible to detect structures that were morphologically compatible with Babesia spp. trophozoites,intra-erythrocyte in vessels, associated to the presence of lesions in the CNS. For the microscopical description all the histological slides of the cases were revised, in addition to new slides were made with the fragments stored in parafin blocks or withthe material fixed in a 10% formalin solution. The clinical course of the animals studied was hyperacute. In 4 cases, there wassudden death within 24 h, from the appearance of the first symptoms and case 7 presented an evolution of approximately 12 h.The main clinical symptoms described were vocalization, anorexia/hyporexia, jaundice and decubitus. Additionally, the mostconsistente macroscopical findings observed...

Candidose sistêmica em cães associada à cinomose / Systemic candidosis in dogs associated with canine distemper virus

Background: Candidosis is an opportunistic fungal infection caused by yeasts of the genus Candida, which normally reside on the surfaces of the mucous membranes and in the skin of several animal species and healthy humans; however the fungi can convert into pathogenic microorganisms and result in invasive infections with systemic involvement due to the impairment of the immune system. Systemic candidosis is rare in dogs and few reports of this mycosis are available in literature. Therefore, the objective of this study was to describe three cases of systemic candidosis associated to canine distemper virus in dogs, highlighting the main epidemiological, clinical and pathological aspects. Cases: Three cases of systemic infection by Candida sp. were diagnosed in dogs. The animals predominantly presented neurological clinical manifestations, followed by unspecific alterations with an evolution of 5 to 30 days. Macroscopically, the lesions were characterized by white-yellowish multifocal to coalescent areas surrounded by reddish borders in the kidneys and heart (cases 1, 2 and 3); liver and submandibular lymph node (case 1); and lung (case 2). In the brains of the three dogs were observed multifocal, blackened and/or reddish and friable areas. In case 1, was observed an increased volume of the right carpometacarpal joint, that when cut, released a reddish and turbid content. In case 2, there was deposition of a whitish lumpy material on the epicardial surface, aorta artery, pericardial sac and spleen; infarction on the right testicle, hydroureter, pyelonephritis and hydronephrosis. Microscopically, the lesions consisted of necrossupurative inflammation associated to hemorrhage, vasculitis, congestion, thrombosis, infarction and fungal structures with distinct morphological patterns which included blastoconidia, pseudohyphae and hyphae. The fungal structures were...

Candidose sistêmica em cães associada à cinomose / Systemic candidosis in dogs associated with canine distemper virus

Background: Candidosis is an opportunistic fungal infection caused by yeasts of the genus Candida, which normally reside on the surfaces of the mucous membranes and in the skin of several animal species and healthy humans; however the fungi can convert into pathogenic microorganisms and result in invasive infections with systemic involvement due to the impairment of the immune system. Systemic candidosis is rare in dogs and few reports of this mycosis are available in literature. Therefore, the objective of this study was to describe three cases of systemic candidosis associated to canine distemper virus in dogs, highlighting the main epidemiological, clinical and pathological aspects. Cases: Three cases of systemic infection by Candida sp. were diagnosed in dogs. The animals predominantly presented neurological clinical manifestations, followed by unspecific alterations with an evolution of 5 to 30 days. Macroscopically, the lesions were characterized by white-yellowish multifocal to coalescent areas surrounded by reddish borders in the kidneys and heart (cases 1, 2 and 3); liver and submandibular lymph node (case 1); and lung (case 2). In the brains of the three dogs were observed multifocal, blackened and/or reddish and friable areas. In case 1, was observed an increased volume of the right carpometacarpal joint, that when cut, released a reddish and turbid content. In case 2, there was deposition of a whitish lumpy material on the epicardial surface, aorta artery, pericardial sac and spleen; infarction on the right testicle, hydroureter, pyelonephritis and hydronephrosis. Microscopically, the lesions consisted of necrossupurative inflammation associated to hemorrhage, vasculitis, congestion, thrombosis, infarction and fungal structures with distinct morphological patterns which included blastoconidia, pseudohyphae and hyphae. The fungal structures were...(AU)

Babesiose encefálica em cães: aspectos clínicos, epidemiológicos e patológicos / Encephalic babesiosis in dogs: clinical, epidemiological and pathological aspects

Background: Babesiosis is a hemolytic disease caused by protozoa of the genus Babesia spp. responsible for causinganemia, fever and splenomegaly in several animal species. The cerebral involvement of babesiosis in dogs manifests itselfin a hyperacute manner with neurological disorders such as motor incoordination, nystagmus, anisocoria and convulsions.In Brazil there still are no studies which describe the pathological aspects of cerebral babesiosis in dogs together withinformation relating to its clinical aspects and epidemiology. Therefore, this work had as an objective to describe sevencases of canine cerebral babesiosis, emphasizing its epidemiological, clinical and pathological aspects.Materials, Methods & Results: All the records of the necropsies performed in dogs at Animal Pathology Laboratory (LPA/HV) of the Federal University of Campina Grande (UFCG), Patos Campus, Paraíba, Northeast of Brazil were identified. In Theperiod from January 2003 to December 2017. Later, were selected all the cases of cerebral babesiosis. Were included in thestudy the cases in which was possible to detect structures that were morphologically compatible with Babesia spp. trophozoites,intra-erythrocyte in vessels, associated to the presence of lesions in the CNS. For the microscopical description all the histological slides of the cases were revised, in addition to new slides were made with the fragments stored in parafin blocks or withthe material fixed in a 10% formalin solution. The clinical course of the animals studied was hyperacute. In 4 cases, there wassudden death within 24 h, from the appearance of the first symptoms and case 7 presented an evolution of approximately 12 h.The main clinical symptoms described were vocalization, anorexia/hyporexia, jaundice and decubitus. Additionally, the mostconsistente macroscopical findings observed...(AU)

Colecistectomía asociada a enterotomia duodenal en una infestación por Platynosomum sp. en un gato doméstico / Cholecystectomy associated to duodenal enterotomy in the infestation by Platynosomum sp. in a domestic cat / Colecistectomia associada à enterotomia duodenal na infestação por Platynosomum sp. em um gato doméstico

Platynosomum sp. es el más grande parásito hepatobiliar de la familia Felidae, causador de una lesión obstructiva extrahepática que puede ser tratada por cirugía. Un felino, sin raza definida, dos años de edad, semidomiciliado, fue atendido con un cuadro clínico de apatía, ictericia, deshidratación y elevación de enzimas hepáticas. En la ecografía abdominal se observó el hígado aumentado, vasos hepáticos y la vena porta con un mayor diámetro, la vesícula llena de contenido anecoico, sedimentación, espesamiento y hiperrefringencia de la pared de el conducto biliar principal dilatado con pared gruesa. Fue realizada colecistectomía con enterotomia duodenal. La inspección de los contenidos de la vesícula biliar reveló parásitos con una apariencia aplanada y la evaluación microscópica fue consistente con Platynosomum sp. El tratamiento con niclosamida y oxibendazol fue efectivo. Colecistectomía asociada con enterotomia duodenal es eficaz en tales casos.(AU)

Platynosomum sp. is the major hepatobiliary parasite of felids, causing an extra-hepatic obstructive lesion which may be treated by surgery. A two-year old cross-bred feline, semi-domiciled, was attended with a clinical picture of apathy, jaundice, dehydration and increase in hepatic enzymes. In the abdominal ultrasonography the liver was observed enlarged, hepatic and portal veins with increased diameter, gall bladder filled by anechoic content, with sediment, thickening and hyperechogenicity of the wall and a dilated main bile duct with a thickened wall. The cholecystectomy with a duodenal enterotomy was performed. The inspection of the gall bladders content revealed parasites with a flattened aspect and the microscopic evaluation was compatible with Platynosomum sp. A treatment with niclosamide and oxibendazole was efficient. Cholecystectomy associated to a duodenal enterotomy is efficient in these cases.(AU)

Platynosomum sp. é o maior parasito hepatobiliar de felídeos, causando uma lesão obstrutiva extra-hepática a qual pode ser tratada por cirurgia. Um felino, de dois anos de idade, sem raça definida, semidomiciliado, foi atendido apresentando um quadro clínico de apatia, icterícia, desidratação e aumento de enzimas hepáticas. Na ultrassonografia abdominal o fígado estava aumentado, vasos hepáticos e veia porta com aumento de diâmetro, vesícula biliar preenchida por conteúdo anecoico, com sedimentação, espessamento e hiperecogenicidade da parede e ducto biliar principal dilatado com parede espessada. Realizou-se a colecistectomia com enterotomia duodenal. A inspeção do conteúdo da vesicular biliar revelou parasitos com um aspecto achatado e a avaliação microscópica foi compatível com Platynosomum sp. O tratamento com niclosamida e oxibendazole foi eficiente. Colecistectomia associada à enterotomia duodenal é eficiente nesses casos.(AU)

Colecistectomía asociada a enterotomia duodenal en una infestación por Platynosomum sp. en un gato doméstico / Cholecystectomy associated to duodenal enterotomy in the infestation by Platynosomum sp. in a domestic cat / Colecistectomia associada à enterotomia duodenal na infestação por Platynosomum sp. em um gato doméstico

Platynosomum sp. es el más grande parásito hepatobiliar de la familia Felidae, causador de una lesión obstructiva extrahepática que puede ser tratada por cirugía. Un felino, sin raza definida, dos años de edad, semidomiciliado, fue atendido con un cuadro clínico de apatía, ictericia, deshidratación y elevación de enzimas hepáticas. En la ecografía abdominal se observó el hígado aumentado, vasos hepáticos y la vena porta con un mayor diámetro, la vesícula llena de contenido anecoico, sedimentación, espesamiento y hiperrefringencia de la pared de el conducto biliar principal dilatado con pared gruesa. Fue realizada colecistectomía con enterotomia duodenal. La inspección de los contenidos de la vesícula biliar reveló parásitos con una apariencia aplanada y la evaluación microscópica fue consistente con Platynosomum sp. El tratamiento con niclosamida y oxibendazol fue efectivo. Colecistectomía asociada con enterotomia duodenal es eficaz en tales casos.

Platynosomum sp. is the major hepatobiliary parasite of felids, causing an extra-hepatic obstructive lesion which may be treated by surgery. A two-year old cross-bred feline, semi-domiciled, was attended with a clinical picture of apathy, jaundice, dehydration and increase in hepatic enzymes. In the abdominal ultrasonography the liver was observed enlarged, hepatic and portal veins with increased diameter, gall bladder filled by anechoic content, with sediment, thickening and hyperechogenicity of the wall and a dilated main bile duct with a thickened wall. The cholecystectomy with a duodenal enterotomy was performed. The inspection of the gall bladder’s content revealed parasites with a flattened aspect and the microscopic evaluation was compatible with Platynosomum sp. A treatment with niclosamide and oxibendazole was efficient. Cholecystectomy associated to a duodenal enterotomy is efficient in these cases.

Platynosomum sp. é o maior parasito hepatobiliar de felídeos, causando uma lesão obstrutiva extra-hepática a qual pode ser tratada por cirurgia. Um felino, de dois anos de idade, sem raça definida, semidomiciliado, foi atendido apresentando um quadro clínico de apatia, icterícia, desidratação e aumento de enzimas hepáticas. Na ultrassonografia abdominal o fígado estava aumentado, vasos hepáticos e veia porta com aumento de diâmetro, vesícula biliar preenchida por conteúdo anecoico, com sedimentação, espessamento e hiperecogenicidade da parede e ducto biliar principal dilatado com parede espessada. Realizou-se a colecistectomia com enterotomia duodenal. A inspeção do conteúdo da vesicular biliar revelou parasitos com um aspecto achatado e a avaliação microscópica foi compatível com Platynosomum sp. O tratamento com niclosamida e oxibendazole foi eficiente. Colecistectomia associada à enterotomia duodenal é eficiente nesses casos.

Enfisema subcutâneo associado a broncopneumonia em um gato - Relato de Caso / Subcutaneous suffering associated with bronchopneumonia in a cat - case report

This is a case report of a feline with a history of diarrhea and moderate subcutaneousemphysema. The animal was subjected to laboratory and radiographic examinations, whereit was proven beyond emphysema, bronchopneumonia. The patient was submitted tohospitalization and was initially medicated with tramadol, ceftriaxone, metronidazole,bromexin and nebulization, and soon after the beginning of the treatment began to presentimprovements, and in the last return it was fully cured.

Enfisema subcutâneo associado a broncopneumonia em um gato - Relato de Caso / Subcutaneous suffering associated with bronchopneumonia in a cat - case report

This is a case report of a feline with a history of diarrhea and moderate subcutaneousemphysema. The animal was subjected to laboratory and radiographic examinations, whereit was proven beyond emphysema, bronchopneumonia. The patient was submitted tohospitalization and was initially medicated with tramadol, ceftriaxone, metronidazole,bromexin and nebulization, and soon after the beginning of the treatment began to presentimprovements, and in the last return it was fully cured.(AU)

Alterações radiográficas de 131 cães com cardiopatia congestiva / Radiographic alterations of 131 dogs with congestive heart disease

The objective of this study was to describe the radiographic alterations of 131 cardiopatic dogs treated at the Small Animals Medical Clinic, Veterinary Hospital of the Federal University of Campina Grande. From January 2007 to December 2012, all clinical records of dogs attended in the routine were selected, by means of selecting animals that had a history, and clinical signs compatible with heart disease. From these, the radiographic examinations were evaluated, describing the alterations found. Cough, fatigue and apathy were the most frequent clinical complaints. Each animal had more than one radiographic alteration, with pulmonary edema (48,1%), HSV greater than 10.5 (42,5%), tracheal dorsal displacement (34,3%), greater contact with the external bone (34,3%) and rounded silhouette (32,8%) the most frequent findings. An extensive knowledge of the radiographic changes related to the cardiological patient should be recognized, in order to aid in the rapid identification of the patients with heart disease.

Aspectos clínicos do tumor venéreo transmissível canino (Tvtc) linfóide, plasmocitóide e misto / Clinical aspects of lymphoid, plasmocytoid and mixed canine transmissible venereal tumor (TVTc)

The objective of this study was to describe the clinical aspects of the subtypes of Canine Transmissible Venereal Tumor (TVTc). The clinical record of 40 dogs with the cytologic diagnosis of TVTc was evaluated. Of these was selected information about classfication, clinical complaint and affected organs with their specific locations. In this study, the plasmocytoid TVTc prevailed. The predominant clinical complaint was penile bleeding (14/40) and vaginal bleeding (13/40). As to the location, genital (G) (34/40) and extragenital (EG) (17/40) tumors were observed, with TVTcL (G-66,66% and EG-66,66%), TVTcM (G-90% and EG-30%) and TVTcP (G-90,47% and EG-38,08%). Among the genitals, the base, body and gland prevailed, and in the vagina: ventral and dorsal floors. In the extragenital tumors, there were changes in the skin, mouth, subcutaneous, nasal region and eye. It was concluded that the TVTcP prevailed more in the skin, while the TVTcL in the head region.

Aspectos clínicos do tumor venéreo transmissível canino (Tvtc) linfóide, plasmocitóide e misto / Clinical aspects of lymphoid, plasmocytoid and mixed canine transmissible venereal tumor (TVTc)

The objective of this study was to describe the clinical aspects of the subtypes of Canine Transmissible Venereal Tumor (TVTc). The clinical record of 40 dogs with the cytologic diagnosis of TVTc was evaluated. Of these was selected information about classfication, clinical complaint and affected organs with their specific locations. In this study, the plasmocytoid TVTc prevailed. The predominant clinical complaint was penile bleeding (14/40) and vaginal bleeding (13/40). As to the location, genital (G) (34/40) and extragenital (EG) (17/40) tumors were observed, with TVTcL (G-66,66% and EG-66,66%), TVTcM (G-90% and EG-30%) and TVTcP (G-90,47% and EG-38,08%). Among the genitals, the base, body and gland prevailed, and in the vagina: ventral and dorsal floors. In the extragenital tumors, there were changes in the skin, mouth, subcutaneous, nasal region and eye. It was concluded that the TVTcP prevailed more in the skin, while the TVTcL in the head region.(AU)

Alterações radiográficas de 131 cães com cardiopatia congestiva / Radiographic alterations of 131 dogs with congestive heart disease

The objective of this study was to describe the radiographic alterations of 131 cardiopatic dogs treated at the Small Animals Medical Clinic, Veterinary Hospital of the Federal University of Campina Grande. From January 2007 to December 2012, all clinical records of dogs attended in the routine were selected, by means of selecting animals that had a history, and clinical signs compatible with heart disease. From these, the radiographic examinations were evaluated, describing the alterations found. Cough, fatigue and apathy were the most frequent clinical complaints. Each animal had more than one radiographic alteration, with pulmonary edema (48,1%), HSV greater than 10.5 (42,5%), tracheal dorsal displacement (34,3%), greater contact with the external bone (34,3%) and rounded silhouette (32,8%) the most frequent findings. An extensive knowledge of the radiographic changes related to the cardiological patient should be recognized, in order to aid in the rapid identification of the patients with heart disease.(AU)

Infección sistémica en herpes simple en una sagui-de-tufo-branco (Callithrix jacchus) en Semiárido em Paraiba / Systemic infection due to herpes simples virus in a white-tufted-ear marmoset (Callithrix jacchus) in the Semiarid Region of Paraiba, Brasil / Infecção sistêmica por herpesvírus simples em um sagui-de-tufo-branco (Callithrix jacchus) no Semiárido da Paraíba

Describe los aspectos epidemiológicos, clínicos y patológicos de la infección por virus del herpes simple en un Sagui-de-tufo-branco (Callithrix jacchus) la región semiárida de Paraíba. La enfermedad se produjo en una hembra de 7 meses de edad que se encontro prostada con lesiones ulcerosas cutáneas y en la cavidad oral. Un niño con lesiones herpéticas orales aparentemente comparte el mismo alimento con el animal. En la necropsia se observaron lesiones vesiculares y ulceradas en la comisura de la boca, el paladar blando y la lengua. Histopatología había dermatitis facial, estomatitis y glositis pustular y ulcerativa asociada con meningoencefalitis no supurativa con vasculitis y corpúsculos inclusiones intranucleares en las células epiteliales, neuronas y células gliales, inclusiones personajes de tipo Cowdry A. El diagnóstico de la infección por virus del herpesvírus simplex se llevó a cabo por datos epidemiológicos, clínicos y patológicos y confirmada por inmunohistoquímica.(AU)

We describe the epidemiological, clinical and pathological aspects of a herpes virus simples infection in a white-tufted-ear marmoset (Callithrix jacchus) in the semiarid region of Paraiba. The disease occurred in a female marmoset, seven-month-old, which presented prostration and ulcerative lesions in the skin and oral cavity. The owners also informed that a child with oral herpetic lesions shared food with the animal. At necropsy, there were vesicular and ulcerative lesions on the labial commissure, soft palate and tongue were observed. On histopathology, there was facial dermatitis, stomatitis and pustular and ulcerative glossitis associated with nonsuppurative meningoencephalitis and vasculitis containing intranuclear Cowdry A type inclusion bodies in epithelial cells, neurons and glial cells. The diagnosis of herpesvirus simplex infection was performed by the epidemiological, clinical and pathological data and confirmed by immunohistochemistry.(AU)

Descrevem-se os aspectos epidemiológicos, clínicos e patológicos da infecção por herpesvírus simples em um sagui-de-tufo branco (Callithrix jacchus) no semiárido da Paraíba. A doença ocorreu em uma fêmea de 7 meses de idade que se apresentava prostrada e com lesões ulcerativas cutâneas e na cavidade oral. Uma criança com lesões orais herpéticas aparentemente compartilhava o mesmo alimento com o animal. Na necropsia, observaram-se lesões vesiculares e ulcerativas na comissura labial, palato mole e na língua. Na histopatologia, verificou-se dermatite facial, estomatite e glossite pustular e ulcerativa associada à meningoencefalite não supurativa com vasculite e corpúsculos de inclusões intranucleares em células epiteliais, neurônios e células da glia, características de inclusões de Cowdry tipo A. O diagnóstico de infecção pelo herpesvírus simplex foi realizado pelos dados epidemiológicos, clínico-patológicos e confirmado pela imuno-histoquímica.(AU)

Infección sistémica en herpes simple en una sagui-de-tufo-branco (Callithrix jacchus) en Semiárido em Paraiba / Systemic infection due to herpes simples virus in a white-tufted-ear marmoset (Callithrix jacchus) in the Semiarid Region of Paraiba, Brasil / Infecção sistêmica por herpesvírus simples em um sagui-de-tufo-branco (Callithrix jacchus) no Semiárido da Paraíba

Describe los aspectos epidemiológicos, clínicos y patológicos de la infección por virus del herpes simple en un Sagui-de-tufo-branco (Callithrix jacchus) la región semiárida de Paraíba. La enfermedad se produjo en una hembra de 7 meses de edad que se encontro prostada con lesiones ulcerosas cutáneas y en la cavidad oral. Un niño con lesiones herpéticas orales aparentemente comparte el mismo alimento con el animal. En la necropsia se observaron lesiones vesiculares y ulceradas en la comisura de la boca, el paladar blando y la lengua. Histopatología había dermatitis facial, estomatitis y glositis pustular y ulcerativa asociada con meningoencefalitis no supurativa con vasculitis y corpúsculos inclusiones intranucleares en las células epiteliales, neuronas y células gliales, inclusiones personajes de tipo Cowdry A. El diagnóstico de la infección por virus del herpesvírus simplex se llevó a cabo por datos epidemiológicos, clínicos y patológicos y confirmada por inmunohistoquímica.

We describe the epidemiological, clinical and pathological aspects of a herpes virus simples infection in a white-tufted-ear marmoset (Callithrix jacchus) in the semiarid region of Paraiba. The disease occurred in a female marmoset, seven-month-old, which presented prostration and ulcerative lesions in the skin and oral cavity. The owners also informed that a child with oral herpetic lesions shared food with the animal. At necropsy, there were vesicular and ulcerative lesions on the labial commissure, soft palate and tongue were observed. On histopathology, there was facial dermatitis, stomatitis and pustular and ulcerative glossitis associated with nonsuppurative meningoencephalitis and vasculitis containing intranuclear Cowdry A type inclusion bodies in epithelial cells, neurons and glial cells. The diagnosis of herpesvirus simplex infection was performed by the epidemiological, clinical and pathological data and confirmed by immunohistochemistry.

Descrevem-se os aspectos epidemiológicos, clínicos e patológicos da infecção por herpesvírus simples em um sagui-de-tufo branco (Callithrix jacchus) no semiárido da Paraíba. A doença ocorreu em uma fêmea de 7 meses de idade que se apresentava prostrada e com lesões ulcerativas cutâneas e na cavidade oral. Uma criança com lesões orais herpéticas aparentemente compartilhava o mesmo alimento com o animal. Na necropsia, observaram-se lesões vesiculares e ulcerativas na comissura labial, palato mole e na língua. Na histopatologia, verificou-se dermatite facial, estomatite e glossite pustular e ulcerativa associada à meningoencefalite não supurativa com vasculite e corpúsculos de inclusões intranucleares em células epiteliais, neurônios e células da glia, características de inclusões de Cowdry tipo A. O diagnóstico de infecção pelo herpesvírus simplex foi realizado pelos dados epidemiológicos, clínico-patológicos e confirmado pela imuno-histoquímica.

Cryptococcal sialoadenitis in a dog

Background: Salivary gland diseases in dogs have an overall incidence of 0.3%. Sialocele and sialoadenitis are the most common injuries and are usually caused by infectious diseases, especially of bacterial origin. Currently, Cryptococcus neoformans has not been registered as the etiological agent since fungal participation is unusual. This case report describes a cryptococcal sialoadenitis in a dog. Case: A 1.9-year-old male poodle had a swelling of the right submandibular region, combined with dry cough and snoring that persisted for about 30 days. The dog often walked in the town square, which has pigeons, and was seen eating chicken droppings. The dog was diagnosed with sialoadenitis in the right submandibular salivary gland. The following laboratory tests were performed cytology, fungal culture, blood count, search for hemoparasites, total plasma protein (ppt), alanine aminotransferase dosage (ALT), alkaline phosphatase (ALP), urea (U), creatinine (CREA), Albumin (ALB), total protein (TP), globulin (GLOB) and amylase (AML). In addition, the dog underwent cervical, thoracic and abdominal ultrasound, and cervical x-rays. The cytology results showed fungal sialoadenitis caused by Cryptococcus neoformans. The blood test results evidenced thrombocytopenia and increased ppt, TP, GLOB, and AML. The lungs and heart x-rays results showed no alterations. However, the proximal third [...]

Cryptococcal sialoadenitis in a dog

Background: Salivary gland diseases in dogs have an overall incidence of 0.3%. Sialocele and sialoadenitis are the most common injuries and are usually caused by infectious diseases, especially of bacterial origin. Currently, Cryptococcus neoformans has not been registered as the etiological agent since fungal participation is unusual. This case report describes a cryptococcal sialoadenitis in a dog. Case: A 1.9-year-old male poodle had a swelling of the right submandibular region, combined with dry cough and snoring that persisted for about 30 days. The dog often walked in the town square, which has pigeons, and was seen eating chicken droppings. The dog was diagnosed with sialoadenitis in the right submandibular salivary gland. The following laboratory tests were performed cytology, fungal culture, blood count, search for hemoparasites, total plasma protein (ppt), alanine aminotransferase dosage (ALT), alkaline phosphatase (ALP), urea (U), creatinine (CREA), Albumin (ALB), total protein (TP), globulin (GLOB) and amylase (AML). In addition, the dog underwent cervical, thoracic and abdominal ultrasound, and cervical x-rays. The cytology results showed fungal sialoadenitis caused by Cryptococcus neoformans. The blood test results evidenced thrombocytopenia and increased ppt, TP, GLOB, and AML. The lungs and heart x-rays results showed no alterations. However, the proximal third [...](AU)