Resumo
Multiple myeloma is a neoplasm characterized by the proliferation of clonal Blymphocytes in the bone marrow, resulting in disordered production ofimmunoglobulins, progressively promoting bone destruction, renal failure,hematopoietic suppression, resulting in several clinical signs in dogs. This work aims toreport a case of multiple myeloma in a 11 - year - old female poodle, who was attendedat a veterinary clinic In the radiographic examination, bone lysis was observed in thedistal third of the femur, which led to the clinical suspicion of bone neoplasia, initiallyconfirmed by cytological analysis of the bone marrow of the site affected by thepresence of atypical plasma cells. The animal was then referred for surgery to performovarian resection (OSH) and removal of a bone biopsy fragment, which can not beperformed. The clinical and cytological diagnoses associated with the surgicalprocedure were essential for the prognosis of the patient.
Assuntos
Feminino , Animais , Cães , Mieloma Múltiplo/cirurgia , Mieloma Múltiplo/veterinária , Linfócitos B , Ovariectomia/veterináriaResumo
Multiple myeloma is a neoplasm characterized by the proliferation of clonal Blymphocytes in the bone marrow, resulting in disordered production ofimmunoglobulins, progressively promoting bone destruction, renal failure,hematopoietic suppression, resulting in several clinical signs in dogs. This work aims toreport a case of multiple myeloma in a 11 - year - old female poodle, who was attendedat a veterinary clinic In the radiographic examination, bone lysis was observed in thedistal third of the femur, which led to the clinical suspicion of bone neoplasia, initiallyconfirmed by cytological analysis of the bone marrow of the site affected by thepresence of atypical plasma cells. The animal was then referred for surgery to performovarian resection (OSH) and removal of a bone biopsy fragment, which can not beperformed. The clinical and cytological diagnoses associated with the surgicalprocedure were essential for the prognosis of the patient.(AU)
Assuntos
Animais , Feminino , Cães , Mieloma Múltiplo/cirurgia , Mieloma Múltiplo/veterinária , Linfócitos B , Ovariectomia/veterináriaResumo
With the purpose of the reduction of costs in swine breeding, the early pregnancy diagnosis is being quite used. The aim of this work was to compare different ultrasonic methods used in the swine"s early pregnancy diagnosis. Sixty-three animals were used, in the following gestation periods: P1 (14-20d), P2 (21-27d), P3 (28-34d) and P4 (35-41d), using the ultrasonic methods: ultrasonic pulse-echo system (Echo), doppler ultrasound (Dpp) and real time B-mode ultrasound (US). After the piglet"s birth, the results were classified as positive, negative, false-positive and false-negative, being calculated the acuity, sensibility and the specificity. The methods were compared by the test of the Qui-square (p 0.05). The acuity and the sensibility of the Echo were only satisfactory, above 50%, starting from P3. Dpp presented many false-positive and false-negative results, not being a safe method. With US, the embryonic vesicles and embryos were visualized at 17 and 27 days of gestation, respectively. US presented acuity (80%) and sensibility (84%) satisfactory in P2, being more precocious and reliable than the others. It was concluded that US was the best method of swine early pregnancy diagnosis, being indicated its use starting from 21 days of gestation.
Com a finalidade de reduzir os custos na suinocultura, o diagnóstico precoce de gestação vem sendo bastante utilizado. O objetivo deste trabalho foi comparar diferentes métodos ultra-sonográficos utilizados no diagnóstico precoce de gestação em suínos. Foram utilizados 63 animais, nos seguintes períodos de gestação: P1 (14-20d), P2 (21-27d), P3 (28-34d) e P4 (35-41d), utilizando os métodos ultrasonográficos eco-ultrassom (eco), doppler (Dpp) e ultrasonografia modo-B (US). Após o parto, os resultados foram classificados como positivos, negativos, falsopositivos e falso-negativos, sendo calculadas a acuidade, a sensibilidade e a especificidade. Os métodos foram comparados pelo teste do Qui-Quadrado (p 0,05). A acuidade e a sensibilidade do Eco somente foram satisfatórias, acima de 50%, a partir de P3. O Dpp apresentou muitos resultados falso-positivos e falso-negativos, não sendo um método seguro. Com a US, as vesículas embrionárias e os embriões foram visualizados aos 17 e 27 dias de gestação, respectivamente. A US apresentou acuidade (80%) e sensibilidade (84%) satisfatórias em P2, sendo mais precoce e confiável que os demais. Concluiu-se que a US é o melhor método de diagnóstico precoce de gestação em suínos, sendo indicado seu uso a partir de 21 dias de gestação.
Resumo
With the purpose of the reduction of costs in swine breeding, the early pregnancy diagnosis is being quite used. The aim of this work was to compare different ultrasonic methods used in the swine"s early pregnancy diagnosis. Sixty-three animals were used, in the following gestation periods: P1 (14-20d), P2 (21-27d), P3 (28-34d) and P4 (35-41d), using the ultrasonic methods: ultrasonic pulse-echo system (Echo), doppler ultrasound (Dpp) and real time B-mode ultrasound (US). After the piglet"s birth, the results were classified as positive, negative, false-positive and false-negative, being calculated the acuity, sensibility and the specificity. The methods were compared by the test of the Qui-square (p 0.05). The acuity and the sensibility of the Echo were only satisfactory, above 50%, starting from P3. Dpp presented many false-positive and false-negative results, not being a safe method. With US, the embryonic vesicles and embryos were visualized at 17 and 27 days of gestation, respectively. US presented acuity (80%) and sensibility (84%) satisfactory in P2, being more precocious and reliable than the others. It was concluded that US was the best method of swine early pregnancy diagnosis, being indicated its use starting from 21 days of gestation.
Com a finalidade de reduzir os custos na suinocultura, o diagnóstico precoce de gestação vem sendo bastante utilizado. O objetivo deste trabalho foi comparar diferentes métodos ultra-sonográficos utilizados no diagnóstico precoce de gestação em suínos. Foram utilizados 63 animais, nos seguintes períodos de gestação: P1 (14-20d), P2 (21-27d), P3 (28-34d) e P4 (35-41d), utilizando os métodos ultrasonográficos eco-ultrassom (eco), doppler (Dpp) e ultrasonografia modo-B (US). Após o parto, os resultados foram classificados como positivos, negativos, falsopositivos e falso-negativos, sendo calculadas a acuidade, a sensibilidade e a especificidade. Os métodos foram comparados pelo teste do Qui-Quadrado (p 0,05). A acuidade e a sensibilidade do Eco somente foram satisfatórias, acima de 50%, a partir de P3. O Dpp apresentou muitos resultados falso-positivos e falso-negativos, não sendo um método seguro. Com a US, as vesículas embrionárias e os embriões foram visualizados aos 17 e 27 dias de gestação, respectivamente. A US apresentou acuidade (80%) e sensibilidade (84%) satisfatórias em P2, sendo mais precoce e confiável que os demais. Concluiu-se que a US é o melhor método de diagnóstico precoce de gestação em suínos, sendo indicado seu uso a partir de 21 dias de gestação.