Metastatic T-cell lymphoma of unknown primary origin in a dog (Canis lupus familiaris)

Canine lymphoma is a hematopoietic neoplasm that can affect different tissues. Its classification is performed according to cellular morphology, clinical stage, immunophenotyping, and anatomical location. However, in some cases, an oncopathy might be in an advanced stage with a plain organic spread, making it impossible to determine the initially affected tissue, which is a rare situation in animals. Thus, a case of metastatic lymphoma, of unknown primary origin, was described in a four-year-old Rottweiler bitch with multiple nodular subcutaneous proliferations. Hematological, biochemical, thoracic radiography, and abdominal ultrasound tests were performed, as well as a cytopathological examination of subcutaneous lesions and bone marrow. Hematologic findings determined anemia, lymphopenia, and thrombocytopenia. The thoracic radiography revealed multiple nodular masses. Cytopathological examination revealed infiltration of malignant lymphocytes into the subcutaneous nodules and into the bone marrow. The dog was euthanized and submitted to necroscopic examination, in which multiple nodules were found in the subcutaneous region, lung, pericardium, gastrointestinal tract and in the skeletal musculature, in addition to lymphadenopathy. Fragments of the affected structures were collected for later histopathological and immunohistochemical evaluation. Histopathological examination re

Canine transmissible venereal tumor with multiple extragenital locations / Tumor venéreo transmissível canino com múltiplas localizações extragenitais

Background: Transmissible venereal tumor (TVT) is a neoplasm which primarily affects the genital mucosa of canines. However, this tumor has been described in several extragenital areas. Although there are no major diffi culties to confirm a TVT when present in the genitalia, it can be confused with several conditions, either neoplastic or non-neoplastic, when located beyond the external reproductive organs. The involvement of multiple extragenital locations is poorly reported, which may compromise the tissues involved and hinder the establishment of a diagnostic conclusion. The study aimed to describe a case of multiple and extragenital TVT in dogs.Case: A two year old mongrel dog had a history of swollen nose and ocular abnormalities. The patient underwent physical examination followed by request of nose and eye cytology. The animal was euthanized and sent for autopsy; the material was intended for cytological diagnosis. It was found an increase in volume in the middle third of the nasal region. In the oral cavity, there was a tumor in the caudal third of the hard palate. Neoformations were also detected in the third eyelid. The nasal and eyelid cytological examination was compatible with TVT plasmacytoid pattern. During the necropsy, it was also detected tumors in the nasal cavity, occupying the space of turbinal bones Proliferation occurred even in the palatine bone and phar

Background: Transmissible venereal tumor (TVT) is a neoplasm which primarily affects the genital mucosa of canines. However, this tumor has been described in several extragenital areas. Although there are no major diffi culties to confirm a TVT when present in the genitalia, it can be confused with several conditions, either neoplastic or non-neoplastic, when located beyond the external reproductive organs. The involvement of multiple extragenital locations is poorly reported, which may compromise the tissues involved and hinder the establishment of a diagnostic conclusion. The study aimed to describe a case of multiple and extragenital TVT in dogs.Case: A two year old mongrel dog had a history of swollen nose and ocular abnormalities. The patient underwent physical examination followed by request of nose and eye cytology. The animal was euthanized and sent for autopsy; the material was intended for cytological diagnosis. It was found an increase in volume in the middle third of the nasal region. In the oral cavity, there was a tumor in the caudal third of the hard palate. Neoformations were also detected in the third eyelid. The nasal and eyelid cytological examination was compatible with TVT plasmacytoid pattern. During the necropsy, it was also detected tumors in the nasal cavity, occupying the space of turbinal bones Proliferation occurred even in the palatine bone and phar

Squamous cell carcinoma of mammary gland in domestic cat / Carcinoma de células escamosas em glândula mamária de gata doméstica

Background: In the feline species, 80% to 93% of neoplasias in the mammary gland are malignant, being the majority carcinomas. Among them, there is the mammary squamous cell carcinoma, which amounts to a very rare neoplasm in the domestic cat, with considerable potential for malignancy. This study aimed to report a case of squamous cell mammary carcinoma in the feline species.Case: A female cat, mixed breed, ten years old, presented history of skin lesion. The cat had been spayed two years before, but with previous administration of contraceptives. At the physical examination, it was observed ulcer between the caudal abdominal mammary glands. The occurrence of skin or mammary neoplasia was conceived. The following complementary tests were requested: complete blood count, serum biochemical profi le (renal and hepatic), chest radiographs, abdominal ultrasound, and incisional biopsy of the ulcerated region periphery, followed by classic histopathology. The lesion histopathology was compatible with squamous cell carcinoma of the mammary gland. Due to such a diagnosis, bilateral mastectomy was recommended. The material obtained during the surgical procedure was sent for anatomopathological analysis. Microscopically, surgical margins infi ltration and a regional lymph node were verifi ed. The owner was advised of the need for complementary therapies and medical monitoring of the cat.

Background: In the feline species, 80% to 93% of neoplasias in the mammary gland are malignant, being the majority carcinomas. Among them, there is the mammary squamous cell carcinoma, which amounts to a very rare neoplasm in the domestic cat, with considerable potential for malignancy. This study aimed to report a case of squamous cell mammary carcinoma in the feline species.Case: A female cat, mixed breed, ten years old, presented history of skin lesion. The cat had been spayed two years before, but with previous administration of contraceptives. At the physical examination, it was observed ulcer between the caudal abdominal mammary glands. The occurrence of skin or mammary neoplasia was conceived. The following complementary tests were requested: complete blood count, serum biochemical profi le (renal and hepatic), chest radiographs, abdominal ultrasound, and incisional biopsy of the ulcerated region periphery, followed by classic histopathology. The lesion histopathology was compatible with squamous cell carcinoma of the mammary gland. Due to such a diagnosis, bilateral mastectomy was recommended. The material obtained during the surgical procedure was sent for anatomopathological analysis. Microscopically, surgical margins infi ltration and a regional lymph node were verifi ed. The owner was advised of the need for complementary therapies and medical monitoring of the cat.

Cutaneous hemangiosarcoma with metastasis in the central nervous system of a canine / Hemangiossarcoma cutâneo com metástase no sistema nervoso central de um canino

Background: Canine hemangiosarcoma is a malignant neoplasm of endothelial cells. Such tumor has most commonly its primary location in the spleen, right atrium, subcutaneous tissue and liver. In general, metastases occur in the liver, omentum, mesentery and lung. The nervous system may be a metastasis site, but with rare spinal cord involvement. This paper aims at the description of canine cutaneous hemangiosarcoma with metastasis to the central nervous system.Case: A dog presented history of skin neoplasia. The patient underwent physical examination, which detected an exophytic tumor in the foreskin. Needle aspiration of the lesion was carried out, suggesting the presence of malignant neoplasm of mesenchymal origin. So, the lesion surgical excision was the option. Before the procedure, complementary preoperative examinations of the patient were required. Those corresponded to chest radiographs, abdominal ultrasound, complete blood count, serum urea, creatinine, alanine aminotransferase, aspartate aminotransferase and total protein. The image diagnostic of the thoracic and abdominal cavities showed no noteworthy changes. The hematology and serum biochemistry were normal. The tumor obtained during surgery was sent for histopathological analysis, whose diagnosis corresponded to hemangiosarcoma. Chemotherapy treatment was not possible in the animal. Nine months after the surgery, a

Background: Canine hemangiosarcoma is a malignant neoplasm of endothelial cells. Such tumor has most commonly its primary location in the spleen, right atrium, subcutaneous tissue and liver. In general, metastases occur in the liver, omentum, mesentery and lung. The nervous system may be a metastasis site, but with rare spinal cord involvement. This paper aims at the description of canine cutaneous hemangiosarcoma with metastasis to the central nervous system.Case: A dog presented history of skin neoplasia. The patient underwent physical examination, which detected an exophytic tumor in the foreskin. Needle aspiration of the lesion was carried out, suggesting the presence of malignant neoplasm of mesenchymal origin. So, the lesion surgical excision was the option. Before the procedure, complementary preoperative examinations of the patient were required. Those corresponded to chest radiographs, abdominal ultrasound, complete blood count, serum urea, creatinine, alanine aminotransferase, aspartate aminotransferase and total protein. The image diagnostic of the thoracic and abdominal cavities showed no noteworthy changes. The hematology and serum biochemistry were normal. The tumor obtained during surgery was sent for histopathological analysis, whose diagnosis corresponded to hemangiosarcoma. Chemotherapy treatment was not possible in the animal. Nine months after the surgery, a

Sporotrichosis in the canine species: a case report on city of mossoro-rn / Esporotricose na espécie canina: relato de um caso na cidade de mossoró-rn

Sporotrichosis is a mycosis caused by Sporothrix schenckii and little frequent in canines. The diagnosis confirmation occurs by fungal isolation in culture medium, but this procedure can be difficult on infected dogs. Because it is rare in canines, its definitive diagnosis is difficult to achieve and due to a lack of reports about the disease in the northeast region of Brazil, the present study aimed to describe a canine sporotrichosis case, in the city of Mossoro, RN. A three-year-old female canine presented chronic cutaneous injuries. The animal was lodged at the backyard, in touch with sand, plants and felines. The dermatological examination showed alopecia and cervical subcutaneous nodules. Cytology, scraping, serology for leishmaniasis and fungal culture were requested. The serological result was not reagent and the scraping showed negative. However, cytology evidenced suggestive structures of S. schenckii on macrophages cytoplasm. The fungal isolation confirmed the sporotrichosis diagnosis. The treatment corresponded to itraconazole. The constant inclusion of sporotrichosis for papules differential diagnosis, nodules and/or cutaneous ulcers is basic on canine species.KEY WORDS: Canine, dermatology, sporotrichosis, Mossoro.

A esporotricose é uma micose causada pelo Sporothrix schenckii e pouco frequente em cães. A confirmação diagnóstica é por isolamento fúngico em meio de cultura, mas este procedimento pode ser difícil em caninos infectados. Em virtude de ser rara nesta espécie, por possuir diagnóstico definitivo difícil e pela carência de relatos da doença no Nordeste brasileiro, o presente trabalho objetivou a descrição de um caso de esporotricose canina, na cidade de Mossoró, RN. Uma cadela, de três anos de idade, apresentava lesões cutâneas crônicas. O animal era alojado em quintal com areia, plantas e felinos peridomiciliados. O exame dermatológico demonstrou alopecia e nódulos subcutâneos cervicais. Exame citológico, raspado cutâneo para pesquisa de ácaro, sorologia para leishmaniose e cultura fúngica foram solicitados. O resultado sorológico foi não reagente e o raspado exibiu negatividade. Porém, a citologia evidenciou estruturas, no citoplasma de macrófagos, sugestivas de S. schenckii. O isolamento do fungo em cultura confirmou o diagnóstico de esporotricose. Fez-se o tratamento com itraconazol. A inclusão constante da esporotricose para o diagnóstico diferencial de pápulas, nódulos e ou úlceras cutâneas é fundamental na espécie canina.  PALAVRAS-CHAVES: Canino, dermatologia, esporotricose, Mossoró.

DERMAL SQUAMOUS CELL CARCINOMA IN GERIATRIC ROOSTER (Gallus gallus domesticus) / CARCINOMA DÉRMICO DE CÉLULAS ESCAMOSAS EM GALO (Gallus gallus domesticus) GERIÁTRICO

The squamous cell carcinoma is more common the malignant epithelial neoplasm of the domestic mammals, even so occurs descriptions in some species of birds. Between the gallinaceous, this tumor is uncommon and the affected animals are in the majority adult and aged. The cutaneous form corresponds most frequent in birds. The squamous cell carcinoma is highly invasive and of changeable malignancy, depending on its localization. The aim of the present study corresponded to the description of a case of dermal squamous cell carcinoma in geriatric rooster. A gallinaceous (Gallus gallus domesticus), male, 10 years of age, was presented with a cutaneous tumor, of gradual growth. The patient was submitted to the physical examination and front to the joined alterations was opted to the surgical debulking of the neoformation. The collected sample was submitted to the histopathological examination. Clinically was evidenced cutaneous tumor, with crusts, inexact limits and tack to adjacent tissues. The same it was located in the distal part of the left hindlimb. The histopathological examination disclosed a compatible morphologic picture with dermal squamous cell carcinoma, moderately differentiated and infiltrate. Three months of after the surgery, signal of return of the neoplasm was observed.KEY WORDS: Cutaneous neoplasm, gallinaceous, squamous cell carcinoma.

O carcinoma de células escamosas é a neoplasia epitelial maligna mais comum dos mamíferos domésticos, embora ocorram descrições em várias espécies de aves. Entre os galináceos, esse tumor é incomum e os animais afetados são na maioria adultos e idosos. A forma cutânea corresponde à mais frequente em aves. O carcinoma de células escamosas é altamente invasivo e de malignidade variável, dependendo da sua localização. Em virtude do reduzido número de relatos de neoplasias cutâneas em aves, o presente trabalho objetivou a descrição de um caso de carcinoma dérmico de células escamosas em um galo doméstico geriátrico. Um galináceo (Gallus gallus domesticus), macho, dez anos de idade, foi apresentado com um tumor cutâneo, de crescimento progressivo. O paciente foi submetido ao exame físico e diante das alterações encontradas optou-se pela excisão cirúrgica da neoformação. Submeteu-se a amostra ao exame histopatológico. Clinicamente, foi constatado um tumor cutâneo ulcerado, com crostas, limites imprecisos e aderência aos tecidos adjacentes, localizado na parte distal do membro pélvico esquerdo. A histopatologia revelou um quadro morfológico compatível com carcinoma dérmico de células escamosas, moderadamente diferenciado e infiltrativo. Transcorridos três meses do pós-cirúrgico, observou-se sinal de recidiva da neoplasia. PALAVRAS-CHAVES: Carcinoma de células escamosas, galináceo, neo

Occurrence of parasitism in Mola mola (Linnaeus, 1758) by metazoan on the coast of Rio Grande do Norte, Brazil / OCORRÊNCIA DE PARASITISMO EM Mola mola (Linnaeus, 1758) POR METAZOÁRIOS NO LITORAL DO RIO GRANDE DO NORTE, BRASIL

The moon-fish (Mola mola) is the largest bony fish in the world, mainly inhabiting tropical and subtropical waters of the Atlantic, Indian and Pacific oceans. This fish is characterized by carrying numerous species of parasites, distributed in its different organs. Therefore, this study aimed to report the metazoan parasites in a moon-fish (M. mola) which was found in death in the coastal city of Areia Branca, Rio Grande do Norte, Brazil. The animal, a young male with 24 Kg, was sent to the Laboratory of Animal Pathology of the University of the Semi-Arid (UFERSA) where necropsy was performed. Due to the alterations found, it was necessary to send samples to the Laboratory of Animal Parasitology of UFERSA. Many parasites were detected in the oral cavity, stomach, duodenum, large intestine, liver, muscle and heart. The parasites were identified as belonging to two taxonomic groups of metazoan: digenetic hemiuridae (compatible with trematode Lecithochirium sp.), and plerocercoids from the order Trypanorhyncha (immature forms of a cestoda pseudophyllidea). The identification of parasites found was of vital importance, since it could estimate the infection by endoparasite communities in marine fish inhabiting the Neotropical region in question. Keywords: Parasites, trematode, cestode, Mola mola, Brazil.

O peixe-lua (Mola mola) é o maior peixe ósseo do mundo, habitando principalmente águas tropicais e subtropicais dos oceanos Atlântico, Índico e Pacífico. Este peixe destaca-se por transportar inúmeras espécies de parasitos, distribuídos em diferentes órgãos. Logo, o presente trabalho objetivou relatar o parasitismo por metazoários em um exemplar de peixe-lua (M. mola) que foi encontrado em óbito no litoral da cidade de Areia Branca, Rio Grande do Norte, Brasil. O animal, um espécime macho, jovem, com 24 Kg, foi encaminhado para o Laboratório de Patologia Animal da Universidade Federal Rural do Semi-Árido (UFERSA) onde foi submetido a necropsia. Em virtude das alterações encontradas, tornou-se necessário o envio de amostras para o Laboratório de Parasitologia Animal da UFERSA. Constataram-se inúmeros parasitos na cavidade oral, estômago, duodeno, intestino grosso, fígado, músculo e coração. Os parasitos foram identificados como pertencentes a dois grupos taxonômicos de metazoários: digenéticos hemiurídeos (compatíveis com o trematódeo Lecithochirium sp.) e plerocercóides da ordem Trypanorhyncha (formas imaturas de um cestódeo pseudofilídeo). A identificação dos parasitos encontrados foi de extrema importância, uma vez que possibilitaria estimar a infecção por comunidades de endoparasitos nos peixes marinhos neotropicais que habitam a região em questão. Palavras-Chave: Parasito

Feline mammary hyperplasia: therapeutic success with the use of the aglepristone / Hiperplasia mamária felina: sucesso terapêutico com o uso do aglepristone

The feline mammary hyperplasia corresponds to a dependent injury of natural or synthetic progesterone. Although it is a benign condition, the clinical presentation, many times, it is an emergency. Thus the use of immediate protocols becomes necessary, as the use of aglepristone, which corresponds to a progesterone-antagonist drug. The aim of the present study corresponded to the description a case of feline mammary hyperplasia, with therapy the base of aglepristone. A feline, female, nine months of age, it presented description of increase of mammary volume, after the administration of a dose of contraceptive (medroxyprogesterone acetate). In virtue of anamnesis and the physical examination the diagnosis of mammary hyperplasia was established and was opted to the use of aglepristone, in the posology of 10mg/kg, to each 24h, during five days, it route subcutaneous. All the mammary glands presented symmetrical hyperplasia, with firm-elastic consistency. From the third day of the administration, it was observed that the glands were with more elastic consistency and lesser volume. After 23 days of the first dose, it had complete regression of the tissue mammary and the animal was neutered. Aglepristone if disclosed as an efficient therapy and insurance. KEY WORDS: Aglepristone, feline, hyperplasia, mammary gland.

A hiperplasia mamária felina corresponde a uma lesão dependente de substâncias progestacionais naturais ou sintéticas. Embora seja uma condição benigna, a apresentação clínica, muitas vezes, é emergencial. Assim, torna-se necessário o uso de protocolos imediatos, como o uso do aglepristone, um fármaco antiprogestágeno. O presente trabalho descreveu um caso de hiperplasia mamária felina, com terapia à base de aglepristone. Um felino, fêmea, siamês, nove meses de idade, apresentou histórico de aumento de volume mamário após administração de uma dose do contraceptivo acetato de medroxiprogesterona. De acordo com a anamnese e o exame físico, foi estabelecido o diagnóstico presuntivo de hiperplasia mamária e optou-se pelo uso do aglepristone na posologia de 10 mg/kg a cada 24 horas, durante cinco dias, via subcutânea. Todos os pares de glândulas mamárias apresentavam hiperplasia simétrica, com consistência firme-elástica. A partir do terceiro dia da administração, observou-se que as glândulas estavam flácidas, consistência mais elástica e menor volume. Transcorridos 23 dias da primeira dose, constatou-se regressão completa do tecido mamário, sendo a gata  submetida à ovariossalpingo-histerectomia. O aglepristone se revelou como uma opção de tratamento eficaz e segura. PALAVRAS-CHAVES: Aglepristone, felino, glândula mamária, hiperplasia,

Freqüência de ácaros em cães e gatos no município de Mossoró, Rio Grande do Norte

Os ectoparasitos são causadores de dermatopatias nos animais domésticos, acometendo, freqüentemente, cães e gatos e podendo assumir um possível potencial zoonótico. Assim, o presente trabalho teve por objetivo descrever a ocorrência de ácaros, causadores de sarnas, em cães e gatos, no município de Mossoró, estado do Rio Grande do Norte. O estudo foi conduzido entre fevereiro de 2002 a janeiro de 2007, no qual foram coletadas amostras de 503 animais (entre cães e gatos), através de raspados cutâneos, individualmente identificados e diagnosticados no Laboratório de Parasitologia Animal da Universidade Federal Rural do Semi-Árido (UFERSA). A análise dos dados foi realizada por meio de freqüência absoluta e relativa. Em relação aos cães, 77 (18,6%) apresentaram alguma espécie de ácaro, com 70 (90,9%) positivos para Demodex canis e 7 (9%) acometidos por Sarcoptes scabiei var. canis, enquanto que, em gatos, os positivos representaram 26 (28,5%) animais, com presença de 18 (69,2%) felinos com Notoedres cati, 4 (15,3%) positivos para S. scabiei e 4 (15,3%) com Lynxacarus radovskyi. Os caninos e felinos estudados apresentaram ácaros distintos.

Tumor venéreo transmissível canino com localização primária e única em cavidade oral

O tumor venéreo transmissível (TVT) pode ser observado na cavidade oral de cães, sem a associação com lesões genitais, sendo assim caracterizado como extragenital e primário. Todavia esta forma possui uma reduzida prevalência. O trabalho objetivou a descrição de um TVT oral primário em canino. Um cão apresentava o histórico de tumor bucal. O animal foi submetido ao exame físico, realizando citologia da neoformação oral. Optou-se pela administração do sulfato de vincristina (0,75 mg/m  2, a cada sete dias, com um total de seis sessões) e prednisolona (1 mg/kg, a cada 24h por sete dias seguido de redução progressiva da dose). Constatou-se um tumor na parte rostral da mandíbula e outro na hemimandíbula direita. O exame citológico diagnosticou TVT de padrão misto. Esta neoplasia não estava presente na genitália externa do animal ou em outras localizações anatômicas. Logo, caracterizou-se o TVT oral como uma forma extragenital e primária. Após a sexta sessão do sulfato de vincristina e finalizada a administração da prednisolona, houve remissão total dos tumores. Deve-se incluir o TVT como diagnóstico diferencial de outras neoformações orais de cães, pois apesar da possibilidade de semelhança macroscópica, ocorre distinção de prognóstico e tratamento.

Tumor venéreo transmissível canino com localização primária e única em cavidade oral

O tumor venéreo transmissível (TVT) pode ser observado na cavidade oral de cães, sem a associação com lesões genitais, sendo assim caracterizado como extragenital e primário. Todavia esta forma possui uma reduzida prevalência. O trabalho objetivou a descrição de um TVT oral primário em canino. Um cão apresentava o histórico de tumor bucal. O animal foi submetido ao exame físico, realizando citologia da neoformação oral. Optou-se pela administração do sulfato de vincristina (0,75 mg/m  2, a cada sete dias, com um total de seis sessões) e prednisolona (1 mg/kg, a cada 24h por sete dias seguido de redução progressiva da dose). Constatou-se um tumor na parte rostral da mandíbula e outro na hemimandíbula direita. O exame citológico diagnosticou TVT de padrão misto. Esta neoplasia não estava presente na genitália externa do animal ou em outras localizações anatômicas. Logo, caracterizou-se o TVT oral como uma forma extragenital e primária. Após a sexta sessão do sulfato de vincristina e finalizada a administração da prednisolona, houve remissão total dos tumores. Deve-se incluir o TVT como diagnóstico diferencial de outras neoformações orais de cães, pois apesar da possibilidade de semelhança macroscópica, ocorre distinção de prognóstico e tratamento.

SPOROTRICHOSIS IN THE CANINE SPECIES: A CASE REPORT ON CITY OF MOSSORO-RN / ESPOROTRICOSE NA ESPÉCIE CANINA: RELATO DE UM CASO NA CIDADE DE MOSSORÓ-RN

Sporotrichosis is a mycosis caused by Sporothrix schenckii and little frequent in canines. The diagnosis confirmation occurs by fungal isolation in culture medium, but this procedure can be difficult on infected dogs. Because it is rare in canines, its definitive diagnosis is difficult to achieve and due to a lack of reports about the disease in the northeast region of Brazil, the present study aimed to describe a canine sporotrichosis case, in the city of Mossoro, RN. A three-year-old female canine presented chronic cutaneous injuries. The animal was lodged at the backyard, in touch with sand, plants and felines. The dermatological examination showed alopecia and cervical subcutaneous nodules. Cytology, scraping, serology for leishmaniasis and fungal culture were requested. The serological result was not reagent and the scraping showed negative. However, cytology evidenced suggestive structures of S. schenckii on macrophages cytoplasm. The fungal isolation confirmed the sporotrichosis diagnosis. The treatment corresponded to itraconazole. The constant inclusion of sporotrichosis for papules differential diagnosis, nodules and/or cutaneous ulcers is basic on canine species.KEY WORDS: Canine, dermatology, sporotrichosis, Mossoro.

A esporotricose é uma micose causada pelo Sporothrix schenckii e pouco frequente em cães. A confirmação diagnóstica é por isolamento fúngico em meio de cultura, mas este procedimento pode ser difícil em caninos infectados. Em virtude de ser rara nesta espécie, por possuir diagnóstico definitivo difícil e pela carência de relatos da doença no Nordeste brasileiro, o presente trabalho objetivou a descrição de um caso de esporotricose canina, na cidade de Mossoró, RN. Uma cadela, de três anos de idade, apresentava lesões cutâneas crônicas. O animal era alojado em quintal com areia, plantas e felinos peridomiciliados. O exame dermatológico demonstrou alopecia e nódulos subcutâneos cervicais. Exame citológico, raspado cutâneo para pesquisa de ácaro, sorologia para leishmaniose e cultura fúngica foram solicitados. O resultado sorológico foi não reagente e o raspado exibiu negatividade. Porém, a citologia evidenciou estruturas, no citoplasma de macrófagos, sugestivas de S. schenckii. O isolamento do fungo em cultura confirmou o diagnóstico de esporotricose. Fez-se o tratamento com itraconazol. A inclusão constante da esporotricose para o diagnóstico diferencial de pápulas, nódulos e ou úlceras cutâneas é fundamental na espécie canina.  PALAVRAS-CHAVES: Canino, dermatologia, esporotricose, Mossoró.

Squamous cell carcinoma of mammary gland in domestic cat / Carcinoma de células escamosas em glândula mamária de gata doméstica

Background: In the feline species, 80% to 93% of neoplasias in the mammary gland are malignant, being the majority carcinomas. Among them, there is the mammary squamous cell carcinoma, which amounts to a very rare neoplasm in the domestic cat, with considerable potential for malignancy. This study aimed to report a case of squamous cell mammary carcinoma in the feline species.Case: A female cat, mixed breed, ten years old, presented history of skin lesion. The cat had been spayed two years before, but with previous administration of contraceptives. At the physical examination, it was observed ulcer between the caudal abdominal mammary glands. The occurrence of skin or mammary neoplasia was conceived. The following complementary tests were requested: complete blood count, serum biochemical profi le (renal and hepatic), chest radiographs, abdominal ultrasound, and incisional biopsy of the ulcerated region periphery, followed by classic histopathology. The lesion histopathology was compatible with squamous cell carcinoma of the mammary gland. Due to such a diagnosis, bilateral mastectomy was recommended. The material obtained during the surgical procedure was sent for anatomopathological analysis. Microscopically, surgical margins infi ltration and a regional lymph node were verifi ed. The owner was advised of the need for complementary therapies and medical monitoring of the cat.

Background: In the feline species, 80% to 93% of neoplasias in the mammary gland are malignant, being the majority carcinomas. Among them, there is the mammary squamous cell carcinoma, which amounts to a very rare neoplasm in the domestic cat, with considerable potential for malignancy. This study aimed to report a case of squamous cell mammary carcinoma in the feline species.Case: A female cat, mixed breed, ten years old, presented history of skin lesion. The cat had been spayed two years before, but with previous administration of contraceptives. At the physical examination, it was observed ulcer between the caudal abdominal mammary glands. The occurrence of skin or mammary neoplasia was conceived. The following complementary tests were requested: complete blood count, serum biochemical profi le (renal and hepatic), chest radiographs, abdominal ultrasound, and incisional biopsy of the ulcerated region periphery, followed by classic histopathology. The lesion histopathology was compatible with squamous cell carcinoma of the mammary gland. Due to such a diagnosis, bilateral mastectomy was recommended. The material obtained during the surgical procedure was sent for anatomopathological analysis. Microscopically, surgical margins infi ltration and a regional lymph node were verifi ed. The owner was advised of the need for complementary therapies and medical monitoring of the cat.

DERMAL SQUAMOUS CELL CARCINOMA IN GERIATRIC ROOSTER (Gallus gallus domesticus) / CARCINOMA DÉRMICO DE CÉLULAS ESCAMOSAS EM GALO (Gallus gallus domesticus) GERIÁTRICO

The squamous cell carcinoma is more common the malignant epithelial neoplasm of the domestic mammals, even so occurs descriptions in some species of birds. Between the gallinaceous, this tumor is uncommon and the affected animals are in the majority adult and aged. The cutaneous form corresponds most frequent in birds. The squamous cell carcinoma is highly invasive and of changeable malignancy, depending on its localization. The aim of the present study corresponded to the description of a case of dermal squamous cell carcinoma in geriatric rooster. A gallinaceous (Gallus gallus domesticus), male, 10 years of age, was presented with a cutaneous tumor, of gradual growth. The patient was submitted to the physical examination and front to the joined alterations was opted to the surgical debulking of the neoformation. The collected sample was submitted to the histopathological examination. Clinically was evidenced cutaneous tumor, with crusts, inexact limits and tack to adjacent tissues. The same it was located in the distal part of the left hindlimb. The histopathological examination disclosed a compatible morphologic picture with dermal squamous cell carcinoma, moderately differentiated and infiltrate. Three months of after the surgery, signal of return of the neoplasm was observed.KEY WORDS: Cutaneous neoplasm, gallinaceous, squamous cell carcinoma.

O carcinoma de células escamosas é a neoplasia epitelial maligna mais comum dos mamíferos domésticos, embora ocorram descrições em várias espécies de aves. Entre os galináceos, esse tumor é incomum e os animais afetados são na maioria adultos e idosos. A forma cutânea corresponde à mais frequente em aves. O carcinoma de células escamosas é altamente invasivo e de malignidade variável, dependendo da sua localização. Em virtude do reduzido número de relatos de neoplasias cutâneas em aves, o presente trabalho objetivou a descrição de um caso de carcinoma dérmico de células escamosas em um galo doméstico geriátrico. Um galináceo (Gallus gallus domesticus), macho, dez anos de idade, foi apresentado com um tumor cutâneo, de crescimento progressivo. O paciente foi submetido ao exame físico e diante das alterações encontradas optou-se pela excisão cirúrgica da neoformação. Submeteu-se a amostra ao exame histopatológico. Clinicamente, foi constatado um tumor cutâneo ulcerado, com crostas, limites imprecisos e aderência aos tecidos adjacentes, localizado na parte distal do membro pélvico esquerdo. A histopatologia revelou um quadro morfológico compatível com carcinoma dérmico de células escamosas, moderadamente diferenciado e infiltrativo. Transcorridos três meses do pós-cirúrgico, observou-se sinal de recidiva da neoplasia. PALAVRAS-CHAVES: Carcinoma de células escamosas, galináceo, neo

Cutaneous hemangiosarcoma with metastasis in the central nervous system of a canine / Hemangiossarcoma cutâneo com metástase no sistema nervoso central de um canino

Background: Canine hemangiosarcoma is a malignant neoplasm of endothelial cells. Such tumor has most commonly its primary location in the spleen, right atrium, subcutaneous tissue and liver. In general, metastases occur in the liver, omentum, mesentery and lung. The nervous system may be a metastasis site, but with rare spinal cord involvement. This paper aims at the description of canine cutaneous hemangiosarcoma with metastasis to the central nervous system.Case: A dog presented history of skin neoplasia. The patient underwent physical examination, which detected an exophytic tumor in the foreskin. Needle aspiration of the lesion was carried out, suggesting the presence of malignant neoplasm of mesenchymal origin. So, the lesion surgical excision was the option. Before the procedure, complementary preoperative examinations of the patient were required. Those corresponded to chest radiographs, abdominal ultrasound, complete blood count, serum urea, creatinine, alanine aminotransferase, aspartate aminotransferase and total protein. The image diagnostic of the thoracic and abdominal cavities showed no noteworthy changes. The hematology and serum biochemistry were normal. The tumor obtained during surgery was sent for histopathological analysis, whose diagnosis corresponded to hemangiosarcoma. Chemotherapy treatment was not possible in the animal. Nine months after the surgery, a

Background: Canine hemangiosarcoma is a malignant neoplasm of endothelial cells. Such tumor has most commonly its primary location in the spleen, right atrium, subcutaneous tissue and liver. In general, metastases occur in the liver, omentum, mesentery and lung. The nervous system may be a metastasis site, but with rare spinal cord involvement. This paper aims at the description of canine cutaneous hemangiosarcoma with metastasis to the central nervous system.Case: A dog presented history of skin neoplasia. The patient underwent physical examination, which detected an exophytic tumor in the foreskin. Needle aspiration of the lesion was carried out, suggesting the presence of malignant neoplasm of mesenchymal origin. So, the lesion surgical excision was the option. Before the procedure, complementary preoperative examinations of the patient were required. Those corresponded to chest radiographs, abdominal ultrasound, complete blood count, serum urea, creatinine, alanine aminotransferase, aspartate aminotransferase and total protein. The image diagnostic of the thoracic and abdominal cavities showed no noteworthy changes. The hematology and serum biochemistry were normal. The tumor obtained during surgery was sent for histopathological analysis, whose diagnosis corresponded to hemangiosarcoma. Chemotherapy treatment was not possible in the animal. Nine months after the surgery, a

FELINE MAMMARY HYPERPLASIA: THERAPEUTIC SUCCESS WITH THE USE OF THE AGLEPRISTONE / HIPERPLASIA MAMÁRIA FELINA: SUCESSO TERAPÊUTICO COM O USO DO AGLEPRISTONE

The feline mammary hyperplasia corresponds to a dependent injury of natural or synthetic progesterone. Although it is a benign condition, the clinical presentation, many times, it is an emergency. Thus the use of immediate protocols becomes necessary, as the use of aglepristone, which corresponds to a progesterone-antagonist drug. The aim of the present study corresponded to the description a case of feline mammary hyperplasia, with therapy the base of aglepristone. A feline, female, nine months of age, it presented description of increase of mammary volume, after the administration of a dose of contraceptive (medroxyprogesterone acetate). In virtue of anamnesis and the physical examination the diagnosis of mammary hyperplasia was established and was opted to the use of aglepristone, in the posology of 10mg/kg, to each 24h, during five days, it route subcutaneous. All the mammary glands presented symmetrical hyperplasia, with firm-elastic consistency. From the third day of the administration, it was observed that the glands were with more elastic consistency and lesser volume. After 23 days of the first dose, it had complete regression of the tissue mammary and the animal was neutered. Aglepristone if disclosed as an efficient therapy and insurance. KEY WORDS: Aglepristone, feline, hyperplasia, mammary gland.

A hiperplasia mamária felina corresponde a uma lesão dependente de substâncias progestacionais naturais ou sintéticas. Embora seja uma condição benigna, a apresentação clínica, muitas vezes, é emergencial. Assim, torna-se necessário o uso de protocolos imediatos, como o uso do aglepristone, um fármaco antiprogestágeno. O presente trabalho descreveu um caso de hiperplasia mamária felina, com terapia à base de aglepristone. Um felino, fêmea, siamês, nove meses de idade, apresentou histórico de aumento de volume mamário após administração de uma dose do contraceptivo acetato de medroxiprogesterona. De acordo com a anamnese e o exame físico, foi estabelecido o diagnóstico presuntivo de hiperplasia mamária e optou-se pelo uso do aglepristone na posologia de 10 mg/kg a cada 24 horas, durante cinco dias, via subcutânea. Todos os pares de glândulas mamárias apresentavam hiperplasia simétrica, com consistência firme-elástica. A partir do terceiro dia da administração, observou-se que as glândulas estavam flácidas, consistência mais elástica e menor volume. Transcorridos 23 dias da primeira dose, constatou-se regressão completa do tecido mamário, sendo a gata  submetida à ovariossalpingo-histerectomia. O aglepristone se revelou como uma opção de tratamento eficaz e segura. PALAVRAS-CHAVES: Aglepristone, felino, glândula mamária, hiperplasia,

Freqüência de ácaros em cães e gatos no município de Mossoró, Rio Grande do Norte

Os ectoparasitos são causadores de dermatopatias nos animais domésticos, acometendo, freqüentemente, cães e gatos e podendo assumir um possível potencial zoonótico. Assim, o presente trabalho teve por objetivo descrever a ocorrência de ácaros, causadores de sarnas, em cães e gatos, no município de Mossoró, estado do Rio Grande do Norte. O estudo foi conduzido entre fevereiro de 2002 a janeiro de 2007, no qual foram coletadas amostras de 503 animais (entre cães e gatos), através de raspados cutâneos, individualmente identificados e diagnosticados no Laboratório de Parasitologia Animal da Universidade Federal Rural do Semi-Árido (UFERSA). A análise dos dados foi realizada por meio de freqüência absoluta e relativa. Em relação aos cães, 77 (18,6%) apresentaram alguma espécie de ácaro, com 70 (90,9%) positivos para Demodex canis e 7 (9%) acometidos por Sarcoptes scabiei var. canis, enquanto que, em gatos, os positivos representaram 26 (28,5%) animais, com presença de 18 (69,2%) felinos com Notoedres cati, 4 (15,3%) positivos para S. scabiei e 4 (15,3%) com Lynxacarus radovskyi. Os caninos e felinos estudados apresentaram ácaros distintos.

Freqüência de ácaros em cães e gatos no município de Mossoró, Rio Grande do Norte

Os ectoparasitos são causadores de dermatopatias nos animais domésticos, acometendo, freqüentemente, cães e gatos e podendo assumir um possível potencial zoonótico. Assim, o presente trabalho teve por objetivo descrever a ocorrência de ácaros, causadores de sarnas, em cães e gatos, no município de Mossoró, estado do Rio Grande do Norte. O estudo foi conduzido entre fevereiro de 2002 a janeiro de 2007, no qual foram coletadas amostras de 503 animais (entre cães e gatos), através de raspados cutâneos, individualmente identificados e diagnosticados no Laboratório de Parasitologia Animal da Universidade Federal Rural do Semi-Árido (UFERSA). A análise dos dados foi realizada por meio de freqüência absoluta e relativa. Em relação aos cães, 77 (18,6%) apresentaram alguma espécie de ácaro, com 70 (90,9%) positivos para Demodex canis e 7 (9%) acometidos por Sarcoptes scabiei var. canis, enquanto que, em gatos, os positivos representaram 26 (28,5%) animais, com presença de 18 (69,2%) felinos com Notoedres cati, 4 (15,3%) positivos para S. scabiei e 4 (15,3%) com Lynxacarus radovskyi. Os caninos e felinos estudados apresentaram ácaros distintos.

Freqüência de ácaros em cães e gatos no município de Mossoró, Rio Grande do Norte

Os ectoparasitos são causadores de dermatopatias nos animais domésticos, acometendo, freqüentemente, cães e gatos e podendo assumir um possível potencial zoonótico. Assim, o presente trabalho teve por objetivo descrever a ocorrência de ácaros, causadores de sarnas, em cães e gatos, no município de Mossoró, estado do Rio Grande do Norte. O estudo foi conduzido entre fevereiro de 2002 a janeiro de 2007, no qual foram coletadas amostras de 503 animais (entre cães e gatos), através de raspados cutâneos, individualmente identificados e diagnosticados no Laboratório de Parasitologia Animal da Universidade Federal Rural do Semi-Árido (UFERSA). A análise dos dados foi realizada por meio de freqüência absoluta e relativa. Em relação aos cães, 77 (18,6%) apresentaram alguma espécie de ácaro, com 70 (90,9%) positivos para Demodex canis e 7 (9%) acometidos por Sarcoptes scabiei var. canis, enquanto que, em gatos, os positivos representaram 26 (28,5%) animais, com presença de 18 (69,2%) felinos com Notoedres cati, 4 (15,3%) positivos para S. scabiei e 4 (15,3%) com Lynxacarus radovskyi. Os caninos e felinos estudados apresentaram ácaros distintos.

Freqüência de ácaros em cães e gatos no município de Mossoró, Rio Grande do Norte

Os ectoparasitos são causadores de dermatopatias nos animais domésticos, acometendo, freqüentemente, cães e gatos e podendo assumir um possível potencial zoonótico. Assim, o presente trabalho teve por objetivo descrever a ocorrência de ácaros, causadores de sarnas, em cães e gatos, no município de Mossoró, estado do Rio Grande do Norte. O estudo foi conduzido entre fevereiro de 2002 a janeiro de 2007, no qual foram coletadas amostras de 503 animais (entre cães e gatos), através de raspados cutâneos, individualmente identificados e diagnosticados no Laboratório de Parasitologia Animal da Universidade Federal Rural do Semi-Árido (UFERSA). A análise dos dados foi realizada por meio de freqüência absoluta e relativa. Em relação aos cães, 77 (18,6%) apresentaram alguma espécie de ácaro, com 70 (90,9%) positivos para Demodex canis e 7 (9%) acometidos por Sarcoptes scabiei var. canis, enquanto que, em gatos, os positivos representaram 26 (28,5%) animais, com presença de 18 (69,2%) felinos com Notoedres cati, 4 (15,3%) positivos para S. scabiei e 4 (15,3%) com Lynxacarus radovskyi. Os caninos e felinos estudados apresentaram ácaros distintos.