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1.
Acta cir. bras ; 37(4): e370405, 2022. tab, ilus
Artigo em Inglês | VETINDEX | ID: biblio-1383299

Resumo

Purpose: To evaluate in-vivo degradation of two bioabsorbable interference screws. Methods: Twenty-two crossbred Santa Inês ewes were used. A poly-DL-lactide (PDLLA) screw (70%/30%) was inserted in the right pelvic limb, and a PDLLA screw (70%) + ß-tri-calcium phosphate (ß-TCP) (30%) in the left pelvic limb. Animals were euthanized at one, four, seven and a half and 18 months after surgery. Plain radiography, computed tomography (CT), microCT, and histological analysis were accomplished. Results: PDLLA screw was hypodense at all evaluation moments, but with progressive density increase along the central axis, whereas PDLLA/ß-TCP was initially hyperdense and progressively lost this characteristic. No adverse reactions were observed on histological evaluation. Conclusions: The inclusion of ß-TCP favors screw degradation since the PDLLA/ß-TCP screws evidenced a more intense degradation process than the PDLLA screws at the last evaluation. PDLLA screws showed higher bone production, evident around the screw thread, inside the lateral perforations, and in the central canal, whereas the PDLLA/ß-TCP screws presented less bone tissue at the implantation site.


Assuntos
Animais , Parafusos Ósseos , Ovinos , Implantes Absorvíveis
2.
Acta sci. vet. (Impr.) ; 49: Pub.1797-2021. ilus
Artigo em Português | VETINDEX | ID: biblio-1458436

Resumo

Background: Osteoarthritis is a degenerative joint disease that affects specially cartilage, meniscus, and tendons. Ligaments, muscles, subchondral bone and synovium. This pathology is a common condition limiting the quality of life ofpatients. Imaging modalities have also been used for evaluation the progression of the osteoarthritis, or degenerative processes induced by acute injury. In order to use more accessible imaging modalities for experimentation, this study aimedto compare radiographic, computed tomography, and ultrasound findings in the evaluation of osteoarthritis induced by thecranial cruciate ligament transection model in rabbits.Materials, Methods & Results: Twenty-four male Norfolk rabbits aged approximately 5 months old were used. All rabbits were submitted to cranial cruciate ligament transection of the left stifle and evaluated 45 days after the surgery. Theradiographic findings were subchondral bone sclerosis (33.33%); joint space narrowing (66%); presence of osteophytesat medial femoral condyle (4.16%), lateral femoral condyle (4.16%), medial fabela (20.83%), lateral fabela (8.33%) andsesamoid of the popliteal muscle (4.16%). No osteophytes were seen at medial and lateral tibial condyles. The tomographiccomputed findings were joint space narrowing (62.5%); presence of osteophytes at medial femoral condyle (75%), lateralfemoral condyle (54.16%), medial fabela (66.66%), lateral fabela (37.5%), medial tibial condyle (75%), lateral tibialcondyle (20.83%) and sesamoid of the popliteal muscle (37.5%). The ultrasound findings were synovial hypertrophy(95.83%); effusion in the suprapatellar recess (75%), distal tibial recess (16.66%) and cranial joint space (75%); changes(hyperechogenic foci and heterogeneity) of the lateral meniscus (50%) and medial meniscus (25%); increased thickness ofthe medial condyle (54.16%) and lateral condyle (45.83%); irregularity of the medial condyle (66.66%) and lateral condyle...


Assuntos
Animais , Coelhos , Osteoartrite do Joelho/diagnóstico por imagem , Osteoartrite do Joelho/veterinária , Radiografia/veterinária , Tomografia/veterinária , Ultrassonografia/veterinária
3.
Acta sci. vet. (Online) ; 49: Pub. 1797, 28 mar. 2021. ilus
Artigo em Português | VETINDEX | ID: vti-30232

Resumo

Background: Osteoarthritis is a degenerative joint disease that affects specially cartilage, meniscus, and tendons. Ligaments, muscles, subchondral bone and synovium. This pathology is a common condition limiting the quality of life ofpatients. Imaging modalities have also been used for evaluation the progression of the osteoarthritis, or degenerative processes induced by acute injury. In order to use more accessible imaging modalities for experimentation, this study aimedto compare radiographic, computed tomography, and ultrasound findings in the evaluation of osteoarthritis induced by thecranial cruciate ligament transection model in rabbits.Materials, Methods & Results: Twenty-four male Norfolk rabbits aged approximately 5 months old were used. All rabbits were submitted to cranial cruciate ligament transection of the left stifle and evaluated 45 days after the surgery. Theradiographic findings were subchondral bone sclerosis (33.33%); joint space narrowing (66%); presence of osteophytesat medial femoral condyle (4.16%), lateral femoral condyle (4.16%), medial fabela (20.83%), lateral fabela (8.33%) andsesamoid of the popliteal muscle (4.16%). No osteophytes were seen at medial and lateral tibial condyles. The tomographiccomputed findings were joint space narrowing (62.5%); presence of osteophytes at medial femoral condyle (75%), lateralfemoral condyle (54.16%), medial fabela (66.66%), lateral fabela (37.5%), medial tibial condyle (75%), lateral tibialcondyle (20.83%) and sesamoid of the popliteal muscle (37.5%). The ultrasound findings were synovial hypertrophy(95.83%); effusion in the suprapatellar recess (75%), distal tibial recess (16.66%) and cranial joint space (75%); changes(hyperechogenic foci and heterogeneity) of the lateral meniscus (50%) and medial meniscus (25%); increased thickness ofthe medial condyle (54.16%) and lateral condyle (45.83%); irregularity of the medial condyle (66.66%) and lateral condyle...(AU)


Assuntos
Animais , Coelhos , Osteoartrite do Joelho/diagnóstico por imagem , Osteoartrite do Joelho/veterinária , Radiografia/veterinária , Tomografia/veterinária , Ultrassonografia/veterinária
4.
Acta cir. bras ; 36(12): e361201, 2021. ilus
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1456246

Resumo

Purpose: To evaluate the effects of the intra-articular application of hyaluronic acid associated with triamcinolone acetonide, and ozone gas in the treatment of induced osteoarthritis in rabbit’s stifles.Methods: Twenty-one Norfolk rabbits were submitted to cranial cruciate ligament transection of the left stifle. After six weeks of the surgery, the rabbits were randomized assigned into three groups: G1 (control) – saline solution (0.9%); G2 – hyaluronic acid associated with triamcinolone; G3 – ozone gas, submitted to three intra-articular applications every seven days. Results: Significant differences occurred: osteophytes at medial femoral condyle (G2 > G1, G2 > G3) on radiography exam; thickening of the medial condyle (G1 > G3, G2 > G3) on ultrasound exam; osteophytes at lateral tibial condyle (G2 > G1, G2 > G3), and medial femoral condyle (G1 > G2, G3 > G1) on computed tomography. Histologically, mean values of chondrocytes in the femur and tibia in G3 and G2 were statistically lower. Conclusions: The intra-articular injection of hyaluronic acid associated with triamcinolone accentuated degenerative joint disease by imaging and macroscopic evaluations, and by histological findings, this treatment and the ozone gas treatment showed similar effects and were inferior to the saline solution (0.9%).


Assuntos
Animais , Coelhos , Osteoartrite do Joelho/tratamento farmacológico , Ozônio , Triancinolona Acetonida/uso terapêutico , Ácido Hialurônico/análise , Ácido Hialurônico/uso terapêutico , Polissacarídeos
5.
J. venom. anim. toxins incl. trop. dis ; 25: e20190027, 2019. tab, graf, ilus
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1040382

Resumo

Bone tissue repair remains a challenge in tissue engineering. Currently, new materials are being applied and often integrated with live cells and biological scaffolds. The fibrin biopolymer (FBP) proposed in this study has hemostatic, sealant, adhesive, scaffolding and drug-delivery properties. The regenerative potential of an association of FBP, biphasic calcium phosphate (BCP) and mesenchymal stem cells (MSCs) was evaluated in defects of rat femurs. Methods: Adult male Wistar rats were submitted to a 5-mm defect in the femur. This was filled with the following materials and/or associations: BPC; FBP and BCP; FBP and MSCs; and BCP, FBP and MSCs. Bone defect without filling was defined as the control group. Thirty and sixty days after the procedure, animals were euthanatized and subjected to computed tomography, scanning electron microscopy and qualitative and quantitative histological analysis. Results: It was shown that FBP is a suitable scaffold for bone defects due to the formation of a stable clot that facilitates the handling and optimizes the surgical procedures, allowing also cell adhesion and proliferation. The association between the materials was biocompatible. Progressive deposition of bone matrix was higher in the group treated with FBP and MSCs. Differentiation of mesenchymal stem cells into osteogenic lineage was not necessary to stimulate bone formation. Conclusions: FBP proved to be an excellent scaffold candidate for bone repair therapies due to application ease and biocompatibility with synthetic calcium-based materials. The satisfactory results obtained by the association of FBP with MSCs may provide a more effective and less costly new approach for bone tissue engineering.(AU)


Assuntos
Animais , Ratos , Biopolímeros , Matriz Óssea , Fibrina , Células-Tronco Mesenquimais , Produtos Biológicos
6.
J. Venom. Anim. Toxins incl. Trop. Dis. ; 25: e.20190027, Nov. 4, 2019. ilus, tab, graf
Artigo em Inglês | VETINDEX | ID: vti-24651

Resumo

Background:Bone tissue repair remains a challenge in tissue engineering. Currently, new materials are being applied and often integrated with live cells and biological scaffolds. The fibrin biopolymer (FBP) proposed in this study has hemostatic, sealant, adhesive, scaffolding and drug-delivery properties. The regenerative potential of an association of FBP, biphasic calcium phosphate (BCP) and mesenchymal stem cells (MSCs) was evaluated in defects of rat femurs.Methods:Adult male Wistar rats were submitted to a 5-mm defect in the femur. This was filled with the following materials and/or associations: BPC; FBP and BCP; FBP and MSCs; and BCP, FBP and MSCs. Bone defect without filling was defined as the control group. Thirty and sixty days after the procedure, animals were euthanatized and subjected to computed tomography, scanning electron microscopy and qualitative and quantitative histological analysis.Results:It was shown that FBP is a suitable scaffold for bone defects due to the formation of a stable clot that facilitates the handling and optimizes the surgical procedures, allowing also cell adhesion and proliferation. The association between the materials was biocompatible. Progressive deposition of bone matrix was higher in the group treated with FBP and MSCs. Differentiation of mesenchymal stem cells into osteogenic lineage was not necessary to stimulate bone formation.Conclusions:FBP proved to be an excellent scaffold candidate for bone repair therapies due to application ease and biocompatibility with synthetic calcium-based materials. The satisfactory results obtained by the association of FBP with MSCs may provide a more effective and less costly new approach for bone tissue engineering.(AU)


Assuntos
Animais , Ratos , Biopolímeros/uso terapêutico , Regeneração Óssea , Adesivo Tecidual de Fibrina/uso terapêutico , Células-Tronco
7.
Acta sci. vet. (Impr.) ; 46(supl): 1-8, 2018. ilus
Artigo em Inglês | VETINDEX | ID: biblio-1457963

Resumo

Background: Adjustable nylon ties polyamide 6.6 is devices produced from the same material of surgical nylon wire and have been used in different surgical procedures in small animals and in human patient. Reports regarding the use of these devices as secondary fixation technique of femoral diaphyseal fractures in animals are rare in the literature. The aim of the present report case was to describe the use of adjustable nylon tie polyamide 6.6 as secondary fixation technique in a 3-year-old dog and 4-month-old cat, diagnosed with femoral diaphyseal fractures.Cases: Case 1. A 3-year-old female dog was presented with reluctance to support the left hind limb, with 5 days’ duration. Pain and edema on the left femoral diaphyseal region was identified. The limb was submitted to radiographic exam and revealed a closed, complete and comminuted fracture of the diaphysis of the femur, and was decided to perform a surgical stabilization by open reduction through primary fixation with intramedullary pin, and secondary fixation of bone fragments with adjustable nylon ties polyamide 6.6, as a substitute of steel cerclage wire. The bone fragments were alignment and fixated with five polyamide nylon ties. The excess was removed with a scalpel blade along the lock. Seven days after surgery the skin sutures were removed and were observed reluctance to support the left hind limb. Physiotherapy sessions were prescribed. Forty days after the surgery was performed a radiographic exam of the left hind limb which revealed alignment of the bone axis. Six months after the surgery, the owner reported that the dog supported the left hind limb. Case 2. A 4-month-old female cat was presented with history of trauma, with 24 h’s duration, and reluctance in supporting the left hind limb. On physical examination there was identified pain on the left femoral diaphyseal region.[...]


Assuntos
Animais , Gatos , Cães , Fios Ortopédicos/tendências , Fios Ortopédicos/veterinária , Fraturas do Fêmur/cirurgia , Fraturas do Fêmur/veterinária , Nylons
8.
Acta sci. vet. (Online) ; 46(supl): 1-8, 2018. ilus
Artigo em Inglês | VETINDEX | ID: vti-19009

Resumo

Background: Adjustable nylon ties polyamide 6.6 is devices produced from the same material of surgical nylon wire and have been used in different surgical procedures in small animals and in human patient. Reports regarding the use of these devices as secondary fixation technique of femoral diaphyseal fractures in animals are rare in the literature. The aim of the present report case was to describe the use of adjustable nylon tie polyamide 6.6 as secondary fixation technique in a 3-year-old dog and 4-month-old cat, diagnosed with femoral diaphyseal fractures.Cases: Case 1. A 3-year-old female dog was presented with reluctance to support the left hind limb, with 5 days duration. Pain and edema on the left femoral diaphyseal region was identified. The limb was submitted to radiographic exam and revealed a closed, complete and comminuted fracture of the diaphysis of the femur, and was decided to perform a surgical stabilization by open reduction through primary fixation with intramedullary pin, and secondary fixation of bone fragments with adjustable nylon ties polyamide 6.6, as a substitute of steel cerclage wire. The bone fragments were alignment and fixated with five polyamide nylon ties. The excess was removed with a scalpel blade along the lock. Seven days after surgery the skin sutures were removed and were observed reluctance to support the left hind limb. Physiotherapy sessions were prescribed. Forty days after the surgery was performed a radiographic exam of the left hind limb which revealed alignment of the bone axis. Six months after the surgery, the owner reported that the dog supported the left hind limb. Case 2. A 4-month-old female cat was presented with history of trauma, with 24 hs duration, and reluctance in supporting the left hind limb. On physical examination there was identified pain on the left femoral diaphyseal region.[...](AU)


Assuntos
Animais , Gatos , Cães , Fraturas do Fêmur/cirurgia , Fraturas do Fêmur/veterinária , Fios Ortopédicos/tendências , Fios Ortopédicos/veterinária , Nylons
9.
Artigo em Inglês, Espanhol, Português | VETINDEX | ID: biblio-1480861

Resumo

Com o rápido desenvolvimento das modalidades de imagem para auxiliar no diagnóstico médico e, por conseguinte, na medicina veterinária, os diagnósticos de diversas enfermidades estão se tornando cada vez mais acessíveis e precisos. Diferentes modalidades de imagem, como ultrassonografia, tomografia computadorizada, ressonância magnética e cintilografia, podem ser utilizadas no diagnóstico de enfermidades tireoidianas, sendo que cada uma possui vantagens e desvantagens. O diagnóstico por imagem é ferramenta auxiliar para o diagnóstico, o tratamento e o prognóstico de doenças tireoidianas. O objetivo do presente trabalho é refletir sobre as limitações e benefícios de cada modalidade de imagem que se encontram disponíveis para o médico veterinário, assim como expor as novas modalidades, a fim de maximizar e tornar mais preciso o diagnóstico de enfermidades tireoidianas.


The diagnosis of various diseases has become more accessible and accurate with the rapid development of imaging modalities aiming to assist in medical diagnosis, and thereby in veterinary medicine. Different diagnostic imaging modalities such as ultrasonography, computed tomography, magnetic resonance imaging and scintigraphy can be performed to obtain information about thyroid diseases, each one with advantages and disadvantages, depending on the thyroid disease in question. Diagnostic imaging is a tool that not only assists in the diagnosis, but also helps treatment and assessment of prognosis of thyroid diseases. The aim of this article is to discuss the limitations and benefits of each diagnostic imaging modality available in the veterinary medical field, and also to present the newest diagnostic imaging modalities in order to maximize and make more accurate diagnosis of thyroid diseases.


Debido al rápido desarrollo de diversas modalidades de diagnóstico por imágenes en medicina humana y, consecuentemente en medicina veterinaria, el diagnóstico de diversas enfermedades está siendo cada vez más accesible y preciso. Existen diferentes modalidades de imagen, como la ecografía, la tomografía computada, la resonancia magnética y la centellografía, que pueden ser utilizadas para el diagnóstico de enfermedades tiroideas, aunque cada una de ellas presenta sus ventajas y desventajas. El diagnóstico por imágenes es una herramienta auxiliar para el diagnóstico, tratamiento y pronóstico de las enfermedades tiroideas. El objetivo del presente trabajo fue analizar las limitaciones y beneficios de cada una de las técnicas de imagen que se encuentran disponibles para el médico veterinario, así como la presentación de nuevas modalidades, con el objetivo de maximizar y hacer más preciso el diagnóstico de las enfermedades tiroideas.


Assuntos
Animais , Cães , Diagnóstico por Imagem/veterinária , Ultrassonografia/veterinária , Cães
10.
Clín. Vet. ; 17(101): 78-79, 2012.
Artigo em Inglês, Espanhol, Português | VETINDEX | ID: vti-10429

Resumo

Com o rápido desenvolvimento das modalidades de imagem para auxiliar no diagnóstico médico e, por conseguinte, na medicina veterinária, os diagnósticos de diversas enfermidades estão se tornando cada vez mais acessíveis e precisos. Diferentes modalidades de imagem, como ultrassonografia, tomografia computadorizada, ressonância magnética e cintilografia, podem ser utilizadas no diagnóstico de enfermidades tireoidianas, sendo que cada uma possui vantagens e desvantagens. O diagnóstico por imagem é ferramenta auxiliar para o diagnóstico, o tratamento e o prognóstico de doenças tireoidianas. O objetivo do presente trabalho é refletir sobre as limitações e benefícios de cada modalidade de imagem que se encontram disponíveis para o médico veterinário, assim como expor as novas modalidades, a fim de maximizar e tornar mais preciso o diagnóstico de enfermidades tireoidianas.(AU)


The diagnosis of various diseases has become more accessible and accurate with the rapid development of imaging modalities aiming to assist in medical diagnosis, and thereby in veterinary medicine. Different diagnostic imaging modalities such as ultrasonography, computed tomography, magnetic resonance imaging and scintigraphy can be performed to obtain information about thyroid diseases, each one with advantages and disadvantages, depending on the thyroid disease in question. Diagnostic imaging is a tool that not only assists in the diagnosis, but also helps treatment and assessment of prognosis of thyroid diseases. The aim of this article is to discuss the limitations and benefits of each diagnostic imaging modality available in the veterinary medical field, and also to present the newest diagnostic imaging modalities in order to maximize and make more accurate diagnosis of thyroid diseases.(AU)


Debido al rápido desarrollo de diversas modalidades de diagnóstico por imágenes en medicina humana y, consecuentemente en medicina veterinaria, el diagnóstico de diversas enfermedades está siendo cada vez más accesible y preciso. Existen diferentes modalidades de imagen, como la ecografía, la tomografía computada, la resonancia magnética y la centellografía, que pueden ser utilizadas para el diagnóstico de enfermedades tiroideas, aunque cada una de ellas presenta sus ventajas y desventajas. El diagnóstico por imágenes es una herramienta auxiliar para el diagnóstico, tratamiento y pronóstico de las enfermedades tiroideas. El objetivo del presente trabajo fue analizar las limitaciones y beneficios de cada una de las técnicas de imagen que se encuentran disponibles para el médico veterinario, así como la presentación de nuevas modalidades, con el objetivo de maximizar y hacer más preciso el diagnóstico de las enfermedades tiroideas.(AU)


Assuntos
Animais , Cães , Ultrassonografia/veterinária , Diagnóstico por Imagem/veterinária , Cães
11.
Botucatu; s.n; 01/08/2011. 90 p.
Tese em Português | VETTESES | ID: vtt-4793

Resumo

A Tomografia Computadorizada (TC), juntamente com a Ressonância Magnética, são modalidades de diagnóstico por imagem avançadas, consideradas de escolha para a avaliação do sistema nervoso, por fornecerem imagens livres de sobreposições e detectarem pequenas diferenças de densidade tecidual. Dentro de qualquer estudo, o conhecimento das possíveis formas de apresentação de cada estrutura e a determinação do limite entre o fisiológico e o alterado são fundamentais para um estudo preciso. O presente trabalho teve como objetivo a descrição dessas variações nas imagens tomográficas do encéfalo, no que diz respeito aos ventrículos laterais e atenuação do parênquima encefálico e cerebelar entre os grupos aqui estipulados (grupo dolicocefálico composto por cães pastores Alemães, grupo mesaticefálico composto por Rottweilers e grupo braquicefálico compostos por cães da raça Boxer) e assim enriquecer a avaliação cerebral à TC e minimizar erros de interpretação. Foram detectadas diversas diferenças individuais e entre os grupos à avaliação qualitativa. Quantitativamente, houve diferença da altura ventricular entre os braquicefálicos e os demais, mostrando que ainda não é possível apenas uma faixa de valores da altura ventricular comum a todos os cães, e que, para as raças braquicefálicas o valor da razão da altura ventricular e encefálica até 25% pode servir como limite superior nos animais hígidos. Os valores de atenuação finais na fase pré-contraste são compatíveis com trabalhos anteriores, o bulbo olfatório e o cerebelo apresentaram-se diferentes estatisticamente em relação aos demais locais. A única raça que teve nas fases simples e contrastada diferenças estatísticas em todos os locais foram os animais do grupo B


Computed tomography (CT) along with Magnetic Ressonance Imaging (MRI) are diagnostic imaging modalities of advanced, considered choice for the evaluation of the nervous system, for providing free images overlap and detect small differences in tissue density. Within any study, knowledge of the possible forms of presentation of each structure and determining the limit between physiological and change are fundamental to a precise study. This study aimed to describe these variations in the tomographic images of the brain, with respect to the lateral ventricles and attenuation of brain parenchyma and cerebellum between the groups set forth herein (dolichocephalic group composed of German shepherd dogs, a group composed of rottweilers and mesaticephalic brachycephalic group consisting of Boxer dogs) and thus enrich the evaluation of brain CT and minimize misunderstandings. We detected several differences between individuals and groups in the qualitative assessment of the aspects mentioned. Quantitatively, there were differences between the ventricular height between brachycephalic and others, showing that it is not possible just a strip of ventricular height values common to all dogs, and that for brachycephalic breeds the value of 25% can serve as upper limit in healthy animals. The final attenuation values in the pre-contrast are consistent with previous works, the olfactory bulb and cerebellum were different statistically when compared to other locations. The only race that was simple and contrasted phases statistical differences in all sites were the animals in group B

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