Trombo tumoral na artéria mesentérica cranial secundária ao leiomiossarcoma intestinal / Tumoral thrombus in cranial mesenteric artery secondary to intestinal leiomyosarcoma

Background: Leiomyosarcoma is a non-encapsulated tumor, belonging to the group of soft tissue sarcomas and often invasive. This histological type comprises the most aggressive solid tumors and, because they respond poorly to therapy, are considered the worst prognosis. The dissemination of metastatic cells can occur mainly hematologically to the liver, lungs and bones or by direct invasion, but metastases to blood vessels are rare and surgery is the treatment of choice in most cases. This paper aims to report a rare case of tumor thrombus in the cranial mesenteric artery secondary to an intestinal leiomyosarcoma.Case: A 9-year-old female S.R.D dog presenting inappetence, evolving to anorexia, weight loss, anemia and vomiting for approximately 15 days was referred to the Hospital of Veterinary Clinics of the Federal University of Rio Grande do Sul. Previous therapy at another clinic with three blood transfusions did not promote reversal of anemia. Ultrasonography revealed a nodule in the small intestine of seven cm in diameter and in the hemogram a hypochromic macrocytic anemia. Thoracic radiography did not reveal metastases. After a new blood transfusion, the patient was referred to an exploratory laparotomy, where the nodule was identified in the small intestine, which was cyanotic and two nodules in the cranial mesenteric artery, partially obstructing the local blood flow. Resection and intestinal anastomosis were performed from the final portion of the duodenum to the cecum, with ligation of the mesenteric artery and the nodules were sent for histopathological analysis. The animal presented a gradual improvement of the condition, with the introduction of liquid feeding on the second postoperative day. After these days, he presented hypochromic macrocytic anemia, with presence of Howell-Jolly corpuscle, spherocytes and icteric plasma, compatible with hemolytic anemia. Treatment with prednisone was started, with a worsening of the condition.[...]

Trombo tumoral na artéria mesentérica cranial secundária ao leiomiossarcoma intestinal / Tumoral thrombus in cranial mesenteric artery secondary to intestinal leiomyosarcoma

Background: Leiomyosarcoma is a non-encapsulated tumor, belonging to the group of soft tissue sarcomas and often invasive. This histological type comprises the most aggressive solid tumors and, because they respond poorly to therapy, are considered the worst prognosis. The dissemination of metastatic cells can occur mainly hematologically to the liver, lungs and bones or by direct invasion, but metastases to blood vessels are rare and surgery is the treatment of choice in most cases. This paper aims to report a rare case of tumor thrombus in the cranial mesenteric artery secondary to an intestinal leiomyosarcoma.Case: A 9-year-old female S.R.D dog presenting inappetence, evolving to anorexia, weight loss, anemia and vomiting for approximately 15 days was referred to the Hospital of Veterinary Clinics of the Federal University of Rio Grande do Sul. Previous therapy at another clinic with three blood transfusions did not promote reversal of anemia. Ultrasonography revealed a nodule in the small intestine of seven cm in diameter and in the hemogram a hypochromic macrocytic anemia. Thoracic radiography did not reveal metastases. After a new blood transfusion, the patient was referred to an exploratory laparotomy, where the nodule was identified in the small intestine, which was cyanotic and two nodules in the cranial mesenteric artery, partially obstructing the local blood flow. Resection and intestinal anastomosis were performed from the final portion of the duodenum to the cecum, with ligation of the mesenteric artery and the nodules were sent for histopathological analysis. The animal presented a gradual improvement of the condition, with the introduction of liquid feeding on the second postoperative day. After these days, he presented hypochromic macrocytic anemia, with presence of Howell-Jolly corpuscle, spherocytes and icteric plasma, compatible with hemolytic anemia. Treatment with prednisone was started, with a worsening of the condition.[...](AU)

Modelo experimental de reconstrução em falha mandibular em coelhos

This paper aims to present a new experimental model of mandibular defect reconstruction in rabbits. It was used 14 animals, in which, in a first stage the left permanent inferior incisive tooth was extracted surgically. After a 50 days period for the bone to fulfill the dentary alveolus, surgery was performed. At first, a 10x5x5mm autograft was removed form the iliac crest, following a partial mandibular failure in the bone with the same auto graft size which was filled with the graft and fixed using titanium microplate. The rabbits were submitted to clinical and radiographic evaluation and 7 of them were euthanasiated at 15 days and the other 7 at 30 days to macro and microscopic analysis. The water and commercial food ingestion was not compromised, and the animals did not showed any chewing or apprehension difficulties, neither pain. Only one animal presented rejection to one screw, without occurring micro plate nor auto graft dislocation. This method showed to be efficient for an experimental model of reconstruction in mandibular defects of rabbits, demonstrating a healing evolution of the graft through radiographic, macroscopic and microscopic exams in 15th and 30th days.

Este trabalho tem como objetivo apresentar um novo modelo experimental de reconstrução em falha mandibular em coelhos. Foram utilizados 14 animais, nos quais, em uma primeira etapa, extraiu-se cirurgicamente o dente incisivo inferior esquerdo permanente. Após um período de 50 dias para o preenchimento ósseo do alvéolo dentário, foi realizada a cirurgia. Inicialmente, coletou-se 10x5x5mm de enxerto ósseo autógeno da crista ilíaca e, em seguida, foi procedida uma falha mandibular parcial de mesmo tamanho, que foi preenchida com o enxerto e fixada com microplaca de titânio. Os coelhos foram submetidos a avaliações clínicas e radiográficas, sendo sete submetidos a eutanásia aos 15 dias e os demais aos 30 dias para análise macro e microscópica. A ingestão de água e ração não foi comprometida, e os animais não apresentaram algia, dificuldade de mastigação e de apreensão. Somente um animal apresentou rejeição a um parafuso, sem ocorrer o deslocamento da placa nem do enxerto. Esse método mostrou-se eficaz como modelo experimental de reconstrução em falha mandibular de coelhos, demonstrando a evolução cicatricial óssea do enxerto por meio dos exames radiográficos, macroscópicos e microscópicos aos 15 e 30 dias.

Modelo experimental de reconstrução em falha mandibular em coelhos

This paper aims to present a new experimental model of mandibular defect reconstruction in rabbits. It was used 14 animals, in which, in a first stage the left permanent inferior incisive tooth was extracted surgically. After a 50 days period for the bone to fulfill the dentary alveolus, surgery was performed. At first, a 10x5x5mm autograft was removed form the iliac crest, following a partial mandibular failure in the bone with the same auto graft size which was filled with the graft and fixed using titanium microplate. The rabbits were submitted to clinical and radiographic evaluation and 7 of them were euthanasiated at 15 days and the other 7 at 30 days to macro and microscopic analysis. The water and commercial food ingestion was not compromised, and the animals did not showed any chewing or apprehension difficulties, neither pain. Only one animal presented rejection to one screw, without occurring micro plate nor auto graft dislocation. This method showed to be efficient for an experimental model of reconstruction in mandibular defects of rabbits, demonstrating a healing evolution of the graft through radiographic, macroscopic and microscopic exams in 15th and 30th days.

Este trabalho tem como objetivo apresentar um novo modelo experimental de reconstrução em falha mandibular em coelhos. Foram utilizados 14 animais, nos quais, em uma primeira etapa, extraiu-se cirurgicamente o dente incisivo inferior esquerdo permanente. Após um período de 50 dias para o preenchimento ósseo do alvéolo dentário, foi realizada a cirurgia. Inicialmente, coletou-se 10x5x5mm de enxerto ósseo autógeno da crista ilíaca e, em seguida, foi procedida uma falha mandibular parcial de mesmo tamanho, que foi preenchida com o enxerto e fixada com microplaca de titânio. Os coelhos foram submetidos a avaliações clínicas e radiográficas, sendo sete submetidos a eutanásia aos 15 dias e os demais aos 30 dias para análise macro e microscópica. A ingestão de água e ração não foi comprometida, e os animais não apresentaram algia, dificuldade de mastigação e de apreensão. Somente um animal apresentou rejeição a um parafuso, sem ocorrer o deslocamento da placa nem do enxerto. Esse método mostrou-se eficaz como modelo experimental de reconstrução em falha mandibular de coelhos, demonstrando a evolução cicatricial óssea do enxerto por meio dos exames radiográficos, macroscópicos e microscópicos aos 15 e 30 dias.

Modelo experimental de reconstrução em falha mandibular em coelhos

This paper aims to present a new experimental model of mandibular defect reconstruction in rabbits. It was used 14 animals, in which, in a first stage the left permanent inferior incisive tooth was extracted surgically. After a 50 days period for the bone to fulfill the dentary alveolus, surgery was performed. At first, a 10x5x5mm autograft was removed form the iliac crest, following a partial mandibular failure in the bone with the same auto graft size which was filled with the graft and fixed using titanium microplate. The rabbits were submitted to clinical and radiographic evaluation and 7 of them were euthanasiated at 15 days and the other 7 at 30 days to macro and microscopic analysis. The water and commercial food ingestion was not compromised, and the animals did not showed any chewing or apprehension difficulties, neither pain. Only one animal presented rejection to one screw, without occurring micro plate nor auto graft dislocation. This method showed to be efficient for an experimental model of reconstruction in mandibular defects of rabbits, demonstrating a healing evolution of the graft through radiographic, macroscopic and microscopic exams in 15th and 30th days.

Este trabalho tem como objetivo apresentar um novo modelo experimental de reconstrução em falha mandibular em coelhos. Foram utilizados 14 animais, nos quais, em uma primeira etapa, extraiu-se cirurgicamente o dente incisivo inferior esquerdo permanente. Após um período de 50 dias para o preenchimento ósseo do alvéolo dentário, foi realizada a cirurgia. Inicialmente, coletou-se 10x5x5mm de enxerto ósseo autógeno da crista ilíaca e, em seguida, foi procedida uma falha mandibular parcial de mesmo tamanho, que foi preenchida com o enxerto e fixada com microplaca de titânio. Os coelhos foram submetidos a avaliações clínicas e radiográficas, sendo sete submetidos a eutanásia aos 15 dias e os demais aos 30 dias para análise macro e microscópica. A ingestão de água e ração não foi comprometida, e os animais não apresentaram algia, dificuldade de mastigação e de apreensão. Somente um animal apresentou rejeição a um parafuso, sem ocorrer o deslocamento da placa nem do enxerto. Esse método mostrou-se eficaz como modelo experimental de reconstrução em falha mandibular de coelhos, demonstrando a evolução cicatricial óssea do enxerto por meio dos exames radiográficos, macroscópicos e microscópicos aos 15 e 30 dias.

Uso do Laser ALGaInP na cicatrização de lesões cutâneas experimentais em coelhos / Use of ALGaInP Laser in the Wound Healing of Experimental Cutaneous Lesions in Rabbits

Background: Animals with extensive cutaneous lesions remain hospitalized for long periods. In addition to increasing treatment costs, this also causes stress in these animals. Low-power laser is widely used to support tissue repair processes. Its use in the treatment of cutaneous wounds has been studied, as it reduces the wound healing period and the consequences caused by the lesion. The study aimed to evaluat the wound healing process of experimental cutaneous wounds in rabbits with the use of laser therapy. Materials, Methods & Results: Ten healthy New Zealand rabbits were used in the study, which were divided in two groups (n=5). Skin biopsies were carried out on day 16 in Group 1 and on day 8 in Group 2. The animals were under general anesthesia for the experimental cutaneous lesion to be carried out. Two 1 cm2 wounds were made on the back of each animal. The lesions were measured by a pachymeter in the immediate postoperative period, then covered with sterile gauze and maintained with rubber bandages. The animals were treated only with Tramadon 3 mg.kg-1 twice a day, during 3 days. Only the lesions on the right side of the animals were irradiated regularly, on each side of the wound, at a distance of 0.5 cm from the margin. The equipment used was a 660 nm wavelength AlGaInP laser diode (Laserpulse, Ibramed), pulsed at a frequency of 20 Hz, at a dose of 3 J and stimulation time of 12 s. The left-side lesions represented the control and the treatment administered to them consisted only of a cleanse using a NaCl solution at 0.9% once a day. The measurement of the lesion area was made every two days with a pachymeter, and the macroscopic characteristics were noted on a control card. For the histological evaluation of the wound healing process, biopsy specimens were taken from the right and left lesions on the sixteenth day in G1 and on the eighth day in G2, by means of a 6mm punch.(...)

Uso do Laser ALGaInP na cicatrização de lesões cutâneas experimentais em coelhos / Use of ALGaInP Laser in the Wound Healing of Experimental Cutaneous Lesions in Rabbits

Background: Animals with extensive cutaneous lesions remain hospitalized for long periods. In addition to increasing treatment costs, this also causes stress in these animals. Low-power laser is widely used to support tissue repair processes. Its use in the treatment of cutaneous wounds has been studied, as it reduces the wound healing period and the consequences caused by the lesion. The study aimed to evaluat the wound healing process of experimental cutaneous wounds in rabbits with the use of laser therapy. Materials, Methods & Results: Ten healthy New Zealand rabbits were used in the study, which were divided in two groups (n=5). Skin biopsies were carried out on day 16 in Group 1 and on day 8 in Group 2. The animals were under general anesthesia for the experimental cutaneous lesion to be carried out. Two 1 cm2 wounds were made on the back of each animal. The lesions were measured by a pachymeter in the immediate postoperative period, then covered with sterile gauze and maintained with rubber bandages. The animals were treated only with Tramadon 3 mg.kg-1 twice a day, during 3 days. Only the lesions on the right side of the animals were irradiated regularly, on each side of the wound, at a distance of 0.5 cm from the margin. The equipment used was a 660 nm wavelength AlGaInP laser diode (Laserpulse, Ibramed), pulsed at a frequency of 20 Hz, at a dose of 3 J and stimulation time of 12 s. The left-side lesions represented the control and the treatment administered to them consisted only of a cleanse using a NaCl solution at 0.9% once a day. The measurement of the lesion area was made every two days with a pachymeter, and the macroscopic characteristics were noted on a control card. For the histological evaluation of the wound healing process, biopsy specimens were taken from the right and left lesions on the sixteenth day in G1 and on the eighth day in G2, by means of a 6mm punch.(...)(AU)

Epidemiological evaluation of the dogs with oral tumors attended in the veterinary hospital of federal university of rio grande do sul / Avaliação epidemiológica de cães com neoplasias orais atendidos no hospital de clínicas veterinárias da universidade federal do rio grande do sul

Oral tumors reach about 6% of all the neoplasm in dogs. The objective of this research was to form an epidemiological study on dogs with oral tumors that have been treated at the Veterinary Hospital of Federal University of rio Grande do Sul from July 2003 to July 2007. The research was conducted within the archives of the histopathology laboratory, using the animals clinical files, in which they had been categorized by breed, sex, age and the tumors histology.  Among the total 79 dogs analyzed, 39 (49.37%) were male and 40 (50.63%) were female. The age range of the dogs spanned from 1 to 16 years, with the average age being 7.7 years. Regarding the types of dogs which were affected by tumors, the most, 16 (19.76%), were mixed breed, followed by the poodle, with 12 cases (14.82%). Malignant neoplasms were found in 50.63% of the cases, and benign neoplasms in 49.37% of the cases. The most common tumors found was the melanoma and acanthomatous epulis with 19 cases each (23.46%), followed by fibrosarcoma and fibrous epulis with 9 cases each (11.11%), plasmocytoma with 8 cases (9.88%), ameloblastoma with 4 cases (4.94%), squamous cell carcinoma and osteosarcoma with 3 cases each (3.7%). Ultimately, this study indicates that malignant tumors were more prevalent than benign, and that the most common histological types of tumors were melanoma, fibrosarcoma, acanthomatous epulis and

Os tumores orais em cães representam cerca de 6% de todas as neoplasias dessa espécie. O objetivo deste trabalho foi realizar um estudo epidemiológico dos cães com tumores orais atendidos no Hospital de Clínicas Veterinárias da Universidade Federal do Rio Grande do Sul durante o período de julho de 2003 a julho de 2007. Realizou-se a pesquisa nos arquivos do Laboratório de Histopatologia e nas fichas clínicas dos animais, para avaliação de dados como raça, sexo, idade e o tipo histológico dos tumores. Procedeu-se à análise de 79 cães, dentre os quais 39 (49,37%) eram machos e 40 (50,63%) eram fêmeas, com idades variando entre um e dezesseis anos (média de 7,7 anos). Os cães mais acometidos foram os sem raça definida, com dezesseis casos (19,76%), seguido pela raça Poodle, com doze casos (14,82%). As neoplasias malignas representaram 50,63% dos casos e as benignas 49,37%%. Os tumores mais comumente encontrados foram o melanoma e o épulis acantomatoso, com dezenove casos cada (23,46%), seguidos pelo fibrossarcoma e o épulis fibromatoso, com nove casos cada (11,11%), plasmocitoma com oito casos (9,88%), ameloblastoma com quatro casos (4,94%), carcinoma epidermoide e osteossarcoma com três casos cada (3,7%). Por meio deste estudo, verificou-se que os tumores malignos apresentam uma maior incidência, e os tipos histológicos mais frequentes foram o melanoma, o fibrossarcoma, o épulis

Uso do Laser ALGaInP na cicatrização de lesões cutâneas experimentais em coelhos

Background:  :  :  : Animals with extensive cutaneous lesions remain hospitalized for long periods. In addition to increasing treatment costs, this also causes stress in these animals. Low-power laser is widely used to support tissue repair processes. Its use in the treatment of cutaneous wounds has been studied, as it reduces the wound healing period and the consequences caused by the lesion. The study aimed to evaluat the wound healing process of experimental cutaneous wounds in rabbits with the use of laser therapy. Materials, Methods & Results: Ten healthy New Zealand rabbits were used in the study, which were divided in two groups (n=5). Skin biopsies were carried out on day 16 in Group 1 and on day 8 in Group 2. The animals were under general anesthesia for the experimental cutaneous lesion to be carried out. Two 1cm2 wounds were made on the back of each animal. The lesions were measured by a pachymeter in the immediate postoperative period, then covered with sterile gauze and maintained with rubber bandages. The animals were treated only with Tramadon 3 mg.kg-1 twice a day, during 3 days. Only the lesions on the right side of the animals were irradiated regularly, on each side of the wound, at a distance of 0.5 cm from the margin. The equipment used was a 660nm wavelength AlGaInP laser diode (Laserpulse, Ibramed), pulsed at a frequency of 20 Hz, at a dose of 3J and s

Uso do Laser ALGaInP na cicatrização de lesões cutâneas experimentais em coelhos

Background:  :  :  : Animals with extensive cutaneous lesions remain hospitalized for long periods. In addition to increasing treatment costs, this also causes stress in these animals. Low-power laser is widely used to support tissue repair processes. Its use in the treatment of cutaneous wounds has been studied, as it reduces the wound healing period and the consequences caused by the lesion. The study aimed to evaluat the wound healing process of experimental cutaneous wounds in rabbits with the use of laser therapy. Materials, Methods & Results: Ten healthy New Zealand rabbits were used in the study, which were divided in two groups (n=5). Skin biopsies were carried out on day 16 in Group 1 and on day 8 in Group 2. The animals were under general anesthesia for the experimental cutaneous lesion to be carried out. Two 1cm2 wounds were made on the back of each animal. The lesions were measured by a pachymeter in the immediate postoperative period, then covered with sterile gauze and maintained with rubber bandages. The animals were treated only with Tramadon 3 mg.kg-1 twice a day, during 3 days. Only the lesions on the right side of the animals were irradiated regularly, on each side of the wound, at a distance of 0.5 cm from the margin. The equipment used was a 660nm wavelength AlGaInP laser diode (Laserpulse, Ibramed), pulsed at a frequency of 20 Hz, at a dose of 3J and s

EPIDEMIOLOGICAL EVALUATION OF THE DOGS WITH ORAL TUMORS ATTENDED IN THE VETERINARY HOSPITAL OF FEDERAL UNIVERSITY OF RIO GRANDE DO SUL / AVALIAÇÃO EPIDEMIOLÓGICA DE CÃES COM NEOPLASIAS ORAIS ATENDIDOS NO HOSPITAL DE CLÍNICAS VETERINÁRIAS DA UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL

Oral tumors reach about 6% of all the neoplasm in dogs. The objective of this research was to form an epidemiological study on dogs with oral tumors that have been treated at the Veterinary Hospital of Federal University of rio Grande do Sul from July 2003 to July 2007. The research was conducted within the archives of the histopathology laboratory, using the animals clinical files, in which they had been categorized by breed, sex, age and the tumors histology.  Among the total 79 dogs analyzed, 39 (49.37%) were male and 40 (50.63%) were female. The age range of the dogs spanned from 1 to 16 years, with the average age being 7.7 years. Regarding the types of dogs which were affected by tumors, the most, 16 (19.76%), were mixed breed, followed by the poodle, with 12 cases (14.82%). Malignant neoplasms were found in 50.63% of the cases, and benign neoplasms in 49.37% of the cases. The most common tumors found was the melanoma and acanthomatous epulis with 19 cases each (23.46%), followed by fibrosarcoma and fibrous epulis with 9 cases each (11.11%), plasmocytoma with 8 cases (9.88%), ameloblastoma with 4 cases (4.94%), squamous cell carcinoma and osteosarcoma with 3 cases each (3.7%). Ultimately, this study indicates that malignant tumors were more prevalent than benign, and that the most common histological types of tumors were melanoma, fibrosarcoma, acanthomatous epulis and

Os tumores orais em cães representam cerca de 6% de todas as neoplasias dessa espécie. O objetivo deste trabalho foi realizar um estudo epidemiológico dos cães com tumores orais atendidos no Hospital de Clínicas Veterinárias da Universidade Federal do Rio Grande do Sul durante o período de julho de 2003 a julho de 2007. Realizou-se a pesquisa nos arquivos do Laboratório de Histopatologia e nas fichas clínicas dos animais, para avaliação de dados como raça, sexo, idade e o tipo histológico dos tumores. Procedeu-se à análise de 79 cães, dentre os quais 39 (49,37%) eram machos e 40 (50,63%) eram fêmeas, com idades variando entre um e dezesseis anos (média de 7,7 anos). Os cães mais acometidos foram os sem raça definida, com dezesseis casos (19,76%), seguido pela raça Poodle, com doze casos (14,82%). As neoplasias malignas representaram 50,63% dos casos e as benignas 49,37%%. Os tumores mais comumente encontrados foram o melanoma e o épulis acantomatoso, com dezenove casos cada (23,46%), seguidos pelo fibrossarcoma e o épulis fibromatoso, com nove casos cada (11,11%), plasmocitoma com oito casos (9,88%), ameloblastoma com quatro casos (4,94%), carcinoma epidermoide e osteossarcoma com três casos cada (3,7%). Por meio deste estudo, verificou-se que os tumores malignos apresentam uma maior incidência, e os tipos histológicos mais frequentes foram o melanoma, o fibrossarcoma, o épulis