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1.
Acta sci., Biol. sci ; 41: e43771, 20190000. tab
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1460863

Resumo

Hexavalent chromium [Cr (VI)] is a metal utilized in different industries and consequently disposed in the environment. It is a toxic substance and its reduction to trivalent Cr [Cr (III)] generates intermediates, which are responsible for the oxidation of molecules, and cause the oxidative stress. Therefore, the aim of this study was to evaluate if Cr (VI) could induce oxidative stress in Wistar rats. In this study, Wistar rats were chronically exposed to 25 and 50 ppm of potassium dichromate in drinking water for 30 days. The levels of Cr were evaluated in the blood and tissues (liver, kidneys, and lungs). Oxidative stress was determined in the liver, kidneys, and lungs and was evaluated by DFCH, TBA-RS and carbonyl test. Antioxidant enzymes were evaluated through catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities. Regarding the results, Cr concentration was significantly elevated in all tissues, however, it was lower in the lungs. In relation to the oxidative stress parameters, there was a significant increase of DCFH levels in the kidneys and carbonyls in liver and kidneys. Regarding the antioxidant enzymes, SOD was decreased in all organs and GPx was diminished in the kidneys. These data indicated that Cr (VI) could induce oxidative stress in the kidneys and liver due to an imbalance between oxidative and antioxidant parameters. The lungs were little affected, possibly by the lowest chromium accumulation.


Assuntos
Animais , Ratos , Cromo , Estresse Oxidativo , Ratos Wistar/fisiologia
2.
Acta Sci. Biol. Sci. ; 41: e43771, 2019. tab
Artigo em Inglês | VETINDEX | ID: vti-763457

Resumo

Hexavalent chromium [Cr (VI)] is a metal utilized in different industries and consequently disposed in the environment. It is a toxic substance and its reduction to trivalent Cr [Cr (III)] generates intermediates, which are responsible for the oxidation of molecules, and cause the oxidative stress. Therefore, the aim of this study was to evaluate if Cr (VI) could induce oxidative stress in Wistar rats. In this study, Wistar rats were chronically exposed to 25 and 50 ppm of potassium dichromate in drinking water for 30 days. The levels of Cr were evaluated in the blood and tissues (liver, kidneys, and lungs). Oxidative stress was determined in the liver, kidneys, and lungs and was evaluated by DFCH, TBA-RS and carbonyl test. Antioxidant enzymes were evaluated through catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities. Regarding the results, Cr concentration was significantly elevated in all tissues, however, it was lower in the lungs. In relation to the oxidative stress parameters, there was a significant increase of DCFH levels in the kidneys and carbonyls in liver and kidneys. Regarding the antioxidant enzymes, SOD was decreased in all organs and GPx was diminished in the kidneys. These data indicated that Cr (VI) could induce oxidative stress in the kidneys and liver due to an imbalance between oxidative and antioxidant parameters. The lungs were little affected, possibly by the lowest chromium accumulation.(AU)


Assuntos
Animais , Ratos , Ratos Wistar/fisiologia , Estresse Oxidativo , Cromo
3.
R. bras. Saúde Prod. Anim. ; 18(4): 542-548, oct.-dec. 2017. tab
Artigo em Inglês | VETINDEX | ID: vti-728578

Resumo

The interaction established between man and their pets has been increasing progressively. The diagnosis of animals carrying methicillin-resistant Staphylococcus pseudintermedius (MRSP) becomes important since positive results for this opportunistic bacteria has been found in humans. The aim of this study was to investigate methicillin-resistant Staphylococcus pseudintermedius (MRSP) in domestic dogs attended in a veterinary clinic and shelter dogs. Anal and nasal swabs from 53 domestic dogs and 46 shelter dogs were collected between the months of August and October of 2015, resulting in 198 samples, which were sent for routine laboratory analysis and subsequently used for this study. Phenotypic tests for bacteria identification and susceptibility to oxacillin were performed for the investigation of MRSP. A total of 23 samples (11.6%) from 21 dogs were positive for S. pseudintermedius, however none of the isolates were MRSP. Nasal and anal swabs had similar positivity and two dogs were carriers of the bacteria in both analyzed sites (anal and nasal). Our results showed a higher positivity for S. pseudintermedius in domestic dogs compared to shelter dogs, as well as indicating the importance of collecting more than one colonization site. This is the first study to perform a comparison among different animal creating sites in Brazil.(AU)


O convívio estabelecido entre o homem e seus animais de estimação vem se intensificando progressivamente. O diagnóstico de animais portadores de Staphylococcus pseudintermedius resistente à meticilina (MRSP) se torna importante uma vez que já foram obtidos resultados positivos para esta bactéria oportunista em humanos. O objetivo do estudo foi pesquisar Staphylococcus pseudintermedius resistente à meticilina (MRSP) em cães domésticos atendidos numa clínica veterinária e em cães de abrigo. Entre os meses de Agosto e Outubro de 2015 foram coletados swabs anais e nasais de 53 cães domésticos e de 46 cães de abrigo, resultando em um total de 198 amostras, as quais foram enviadas para análise de rotina laboratorial na Universidade Feevale e, posteriormente, utilizadas para este estudo. Foram realizados testes fenotípicos de identificação da bactéria e de suscetibilidade à oxacilina para a pesquisa de MRSP. Um total de 23 amostras (11.6%) oriundas de 21 cães foi positivo para S. pseudintermedius, porém nenhum isolado era MRSP. Os swabs nasais e anais tiveram positividade semelhante, sendo dois cães portadores da bactéria em ambos os sítios (anal e nasal). Nossos resultados indicaram uma maior positividade para S. pseudintermedius em cães domésticos em comparação aos cães de abrigo, além de sinalizar sobre a importância de coletas em mais de um sítio de colonização. Este é o primeiro estudo que realizou uma comparação entre os diferentes locais de criação dos animais no Brasil.(AU)


Assuntos
Animais , Cães , Staphylococcus , Resistência a Meticilina , Cães/microbiologia , Pesquisa
4.
Rev. bras. saúde prod. anim ; 18(4): 542-548, oct.-dec. 2017. tab
Artigo em Inglês | VETINDEX | ID: biblio-1493746

Resumo

The interaction established between man and their pets has been increasing progressively. The diagnosis of animals carrying methicillin-resistant Staphylococcus pseudintermedius (MRSP) becomes important since positive results for this opportunistic bacteria has been found in humans. The aim of this study was to investigate methicillin-resistant Staphylococcus pseudintermedius (MRSP) in domestic dogs attended in a veterinary clinic and shelter dogs. Anal and nasal swabs from 53 domestic dogs and 46 shelter dogs were collected between the months of August and October of 2015, resulting in 198 samples, which were sent for routine laboratory analysis and subsequently used for this study. Phenotypic tests for bacteria identification and susceptibility to oxacillin were performed for the investigation of MRSP. A total of 23 samples (11.6%) from 21 dogs were positive for S. pseudintermedius, however none of the isolates were MRSP. Nasal and anal swabs had similar positivity and two dogs were carriers of the bacteria in both analyzed sites (anal and nasal). Our results showed a higher positivity for S. pseudintermedius in domestic dogs compared to shelter dogs, as well as indicating the importance of collecting more than one colonization site. This is the first study to perform a comparison among different animal creating sites in Brazil.


O convívio estabelecido entre o homem e seus animais de estimação vem se intensificando progressivamente. O diagnóstico de animais portadores de Staphylococcus pseudintermedius resistente à meticilina (MRSP) se torna importante uma vez que já foram obtidos resultados positivos para esta bactéria oportunista em humanos. O objetivo do estudo foi pesquisar Staphylococcus pseudintermedius resistente à meticilina (MRSP) em cães domésticos atendidos numa clínica veterinária e em cães de abrigo. Entre os meses de Agosto e Outubro de 2015 foram coletados swabs anais e nasais de 53 cães domésticos e de 46 cães de abrigo, resultando em um total de 198 amostras, as quais foram enviadas para análise de rotina laboratorial na Universidade Feevale e, posteriormente, utilizadas para este estudo. Foram realizados testes fenotípicos de identificação da bactéria e de suscetibilidade à oxacilina para a pesquisa de MRSP. Um total de 23 amostras (11.6%) oriundas de 21 cães foi positivo para S. pseudintermedius, porém nenhum isolado era MRSP. Os swabs nasais e anais tiveram positividade semelhante, sendo dois cães portadores da bactéria em ambos os sítios (anal e nasal). Nossos resultados indicaram uma maior positividade para S. pseudintermedius em cães domésticos em comparação aos cães de abrigo, além de sinalizar sobre a importância de coletas em mais de um sítio de colonização. Este é o primeiro estudo que realizou uma comparação entre os diferentes locais de criação dos animais no Brasil.


Assuntos
Animais , Cães , Cães/microbiologia , Pesquisa , Resistência a Meticilina , Staphylococcus
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