Feline lymphoplasmacytic gingivostomatitis: clinical and anatomopathological aspects

Background: Feline lymphoplasmacytic gingivostomatitis (FLPG) is an idiopathic, multifactorial and highly challengingcondition, since the results of the available treatments are partial and transitory. A set of lesions triggered by inflammatoryreaction is observed, sometimes with ulcerations in the oral mucosa, leading to algia and discomfort. Histopathologicalexamination figures as the definitive diagnostic tool, presenting distinct cellular elements. The present study aims to reportthree cases of FLPG, firstly addressing the anatomopathological findings, as well as the therapeutic approach used andthe results obtained in each case.Cases: Case 1- Occurred in a feline Siamese male 15-year-old, weighing 3.8 kg, which was admitted at a local clinic, underthe complaint of prostration, dysphagia, and weight loss, signs that were noticed approximately 5 days before. Clinicalevaluation revealed multiple proliferative and ulcerative lesions, extending until the isthmus of the fauces, erythematousareas around the teeth and multifocal gingival reabsorption. Once the clinical signs and lesions were observed, samples werecollected for histopathological examination and sent to the Laboratory of Animal Pathology (LAP) of Faculty of Agronomyand Veterinary Medicine of the University of Passo Fundo (FAVM-UPF). Histologically, both fragments presented lymphoplasmacytic infiltration, with large and intensely eosinophilic cytoplasm, often with granular aspect, central to lateralizedhyperchromatic nuclei, located predominantly in lamina propria and mucosa, as well as a discrete Mott cell infiltrate. Itwas also observed the presence of diffuse suppurative chronic inflammatory infiltrate, predominantly in lamina propriaand mucosa, as well as foci of edema and hemorrhage, in addition to loss of tissue architecture establishing the definitivediagnosis of...

Feline lymphoplasmacytic gingivostomatitis: clinical and anatomopathological aspects

Background: Feline lymphoplasmacytic gingivostomatitis (FLPG) is an idiopathic, multifactorial and highly challengingcondition, since the results of the available treatments are partial and transitory. A set of lesions triggered by inflammatoryreaction is observed, sometimes with ulcerations in the oral mucosa, leading to algia and discomfort. Histopathologicalexamination figures as the definitive diagnostic tool, presenting distinct cellular elements. The present study aims to reportthree cases of FLPG, firstly addressing the anatomopathological findings, as well as the therapeutic approach used andthe results obtained in each case.Cases: Case 1- Occurred in a feline Siamese male 15-year-old, weighing 3.8 kg, which was admitted at a local clinic, underthe complaint of prostration, dysphagia, and weight loss, signs that were noticed approximately 5 days before. Clinicalevaluation revealed multiple proliferative and ulcerative lesions, extending until the isthmus of the fauces, erythematousareas around the teeth and multifocal gingival reabsorption. Once the clinical signs and lesions were observed, samples werecollected for histopathological examination and sent to the Laboratory of Animal Pathology (LAP) of Faculty of Agronomyand Veterinary Medicine of the University of Passo Fundo (FAVM-UPF). Histologically, both fragments presented lymphoplasmacytic infiltration, with large and intensely eosinophilic cytoplasm, often with granular aspect, central to lateralizedhyperchromatic nuclei, located predominantly in lamina propria and mucosa, as well as a discrete Mott cell infiltrate. Itwas also observed the presence of diffuse suppurative chronic inflammatory infiltrate, predominantly in lamina propriaand mucosa, as well as foci of edema and hemorrhage, in addition to loss of tissue architecture establishing the definitivediagnosis of...(AU)

Lavado traqueobrônquico auxiliado por endoscópio rígido ou por tubo endotraqueal em cães / Tracheobronchic washing in dogs by means of rigid endoscopy or endotracheal tube

Com o objetivo de se avaliarem os resultados do uso de endoscopia rígida e da técnica por tubo endotraqueal de colheita de líquido traqueobrônquico, foram utilizados 28 cães, errantes ou domiciliados, distribuídos em dois grupos. Nos cães do grupo 1, aplicou-se a técnica de lavado traqueobrônquico em 14 cães, sendo sete sadios e sete com sinais clínicos respiratórios. Nos do grupo 2, utilizou-se a mesma técnica, entretanto com endoscopia rígida, em sete cães sadios e em sete cães com sinais clínicos de doença respiratória. Os dados evidenciaram que o procedimento utilizando-se endoscópio rígido resultou em menor volume de solução infundida e em maior porcentagem de solução recuperada. Não houve diferença significativa quanto ao tempo de duração da execução da técnica. A contagem bacteriana foi mais alta nas amostras coletadas por endoscópio rígido, porém não houve diferença significativa na contagem de células nucleadas totais. Portanto, o uso da endoscopia rígida para colheita de líquido traqueobrônquico mostrou-se mais vantajosa do que a técnica convencional utilizando-se o tubo endotraqueal, pois fornece imagens das vias aéreas e permite acompanhamento visual da lavagem.(AU)

The present study aimed to evaluate the results of rigid endoscopy and endotracheal tube techniques for collecting tracheobronchic fluid from dogs. Twenty eight erratic or housed dogs, were allocated into to two groups. In group 1, tracheobronchic washing was applied to seven healthy dogs and seven dogs with clinical signs of respiratory disease. In group 2, seven healthy and seven dogs with respiratory disease were submitted to endo-bronchial washing by rigid endoscopy. Using rigid endoscopy, a lower volume was introduced but a higher percentage of washing fluid was recovered. There was no difference regarding the time necessary to perform both techniques. Bacterial counts were higher in samples collected by rigid endoscopy, but there was no difference in total nucleated cell counts from these samples. Thus, the use of rigid endoscopy to collect tracheobronchic fluid was found to be advantageous when compared to the conventional technique using endotracheal tube.(AU)

Pododermatite plasmocitária felina: relato de caso / Feline plasma cell pododermatitis: case report

A pododermatite plasmocitária felina é uma doença cutânea rara, cuja etiopatogenia é desconhecida. Entretanto, alguns autores referem que uma base imunológica pode estar associada devido à resposta benéfica à terapia imunossupressora com altas doses de glicocorticóides. É possível ocorrer concomitantemente a uma série de doenças sistêmicas e cutâneas incluindo as imunomediadas, infecciosas e neoplásicas, dentre outras condições diversas. Os dados da literatura são bastante escassos, sendo pouco encontrados no Brasil. O presente estudo relata o caso de um felino fêmea, que apresentava sinais específicos de pododermatite plasmocitária, o qual teve seu diagnóstico confirmado por meio da histopatologia(AU)

Feline plasma cell pododermatitis is a rare skin disease whose etiology is unknown. Some authors report that an immunological basis can be associated due to the beneficial response to immunosuppressive therapy with high doses of glucocorticoids. Several cutaneous diseases can occur simultaneously, including immune mediated dermatitis, infectious and neoplasic affections. The literature data are very scarce, being rarely found in Brazil. The present study reports the case of a feline with specific clinical signs of plasma cell pododermatitis. The diagnosis was confirmed by histopathology(AU)

Pododermatite plasmocitária felina: relato de caso / Feline plasma cell pododermatitis: case report

A pododermatite plasmocitária felina é uma doença cutânea rara, cuja etiopatogenia é desconhecida. Entretanto, alguns autores referem que uma base imunológica pode estar associada devido à resposta benéfica à terapia imunossupressora com altas doses de glicocorticóides. É possível ocorrer concomitantemente a uma série de doenças sistêmicas e cutâneas incluindo as imunomediadas, infecciosas e neoplásicas, dentre outras condições diversas. Os dados da literatura são bastante escassos, sendo pouco encontrados no Brasil. O presente estudo relata o caso de um felino fêmea, que apresentava sinais específicos de pododermatite plasmocitária, o qual teve seu diagnóstico confirmado por meio da histopatologia

Feline plasma cell pododermatitis is a rare skin disease whose etiology is unknown. Some authors report that an immunological basis can be associated due to the beneficial response to immunosuppressive therapy with high doses of glucocorticoids. Several cutaneous diseases can occur simultaneously, including immune mediated dermatitis, infectious and neoplasic affections. The literature data are very scarce, being rarely found in Brazil. The present study reports the case of a feline with specific clinical signs of plasma cell pododermatitis. The diagnosis was confirmed by histopathology

Validação dos critérios de sepse em cães piometra / Validation of sepsis criteria in dogs with pyometra

No presente trabalho procurou-se avaliar as principais alterações clínicas e hematológicas compatíveis com sepse em cadelas com diagnóstico clínico e ultra-sonografia de piometra. Foi realizado um estudo retrospectivo, avaliando a presença de sinais cardeais de sepse, tais como leucocitose ou leucopenia, taquipnéia, taquicardia, hipertemia ou hipotemia. Também foi realizada dosagem sérica de proteína C reativa. Cinqüenta e quatro porcento das cadelas com piometra apresentaram pelo menos dois desses quatro sinais, sugerindo a presença de síndrome sepse. Valores séricos aumentados de proteínas C reativa também foram encontrados, ratificando a informação(AU)

The present study aimed to assess the main clinical and hematological findings compatible with sepsis in female dogs with clinical, ultrasonographic, and surgical diagnosis of pyometra. The authors carried out a retrospective study to evaluate the presence of classic signs of sepsis, such as leukocytosis or leukocytosis or leucopenia, tachypnea, tachycardia, hyperthermia or hypothermia. Serum C-reactive protein levels were measured. Fifthy four percent of them with pyometra showed at leats two classic signs, suggesting the presence of sepsis syndrome. Elevated serum C-reactive protein levels were also found, thus confirming the diagnosis(AU)

Validação dos critérios de sepse em cães piometra / Validation of sepsis criteria in dogs with pyometra

No presente trabalho procurou-se avaliar as principais alterações clínicas e hematológicas compatíveis com sepse em cadelas com diagnóstico clínico e ultra-sonografia de piometra. Foi realizado um estudo retrospectivo, avaliando a presença de sinais cardeais de sepse, tais como leucocitose ou leucopenia, taquipnéia, taquicardia, hipertemia ou hipotemia. Também foi realizada dosagem sérica de proteína C reativa. Cinqüenta e quatro porcento das cadelas com piometra apresentaram pelo menos dois desses quatro sinais, sugerindo a presença de síndrome sepse. Valores séricos aumentados de proteínas C reativa também foram encontrados, ratificando a informação

The present study aimed to assess the main clinical and hematological findings compatible with sepsis in female dogs with clinical, ultrasonographic, and surgical diagnosis of pyometra. The authors carried out a retrospective study to evaluate the presence of classic signs of sepsis, such as leukocytosis or leukocytosis or leucopenia, tachypnea, tachycardia, hyperthermia or hypothermia. Serum C-reactive protein levels were measured. Fifthy four percent of them with pyometra showed at leats two classic signs, suggesting the presence of sepsis syndrome. Elevated serum C-reactive protein levels were also found, thus confirming the diagnosis