Cutaneous hemangiosarcoma in a buff-throated saltator (Saltator maximus) with lung metastasis

Hemangiosarcomas are malignant neoplasms arising from endothelial cells of blood vessels. A three-year-old male buff-throated saltator (Saltator maximus) was referred to the Veterinary Hospital of the Universidade Federal da Paraíba (HV-UFPB) due to a recurrent tan nodular mass in the pericloacal region. Surgery for excision of the mass was attempted but the bird died during the surgical procedure. The nodule and the carcass were sent for gross and histological evaluation. Histopathology revealed large blood-filled vascular spaces lined by pleomorphic endothelial cells, which were also observed in the lungs. These findings suggested the diagnosis of hemangiosarcoma that was confirmed by immunohistochemistry against factor VIII-related antigen.

Cutaneous hemangiosarcoma in a buff-throated saltator (Saltator maximus) with lung metastasis

Hemangiosarcomas are malignant neoplasms arising from endothelial cells of blood vessels. A three-year-old male buff-throated saltator (Saltator maximus) was referred to the Veterinary Hospital of the Universidade Federal da Paraíba (HV-UFPB) due to a recurrent tan nodular mass in the pericloacal region. Surgery for excision of the mass was attempted but the bird died during the surgical procedure. The nodule and the carcass were sent for gross and histological evaluation. Histopathology revealed large blood-filled vascular spaces lined by pleomorphic endothelial cells, which were also observed in the lungs. These findings suggested the diagnosis of hemangiosarcoma that was confirmed by immunohistochemistry against factor VIII-related antigen.(AU)

Tumor maligno da bainha de nervo periférico e osteopatia hipertrófica em cadela / Malignant peripheral nerve sheath tumor and hypertrophic osteopathy in a bitch

Background: Malignant peripheral nerve sheath tumors (MPNSTs) are rare, aggressive, relapsing, metastatic cutaneousneoplasms of mesenchymal origin. So far, no account on the association of this disease with hypertrophic osteopathy (HO)in dogs is available in the literature. Current theories on the possible causes of HO suggest that this disease may be triggered by a primary neoplasm as well as by its metastasis. The objective of this work is to report the clinical, cytological,radiographic, histopathological, and immunohistochemical aspects of a dog affected by MPNST and HO.Case: A 13-year-old female mongrel dog was presented with a history of ulcerated nodular lesion on the skin of the flank.Several ulcerated and non-ulcerated tumors were observed on the thorax, neck, and head at the physical exam. Cytological examination of the nodules revealed presence of mesenchymal cells with a malignant aspect. Complete blood countrevealed anemia. There were no alterations in the biochemical tests performed. Thoracic radiographs showed presence of anodular interstitial pattern in the cranial, medial, and caudal lobes of the lungs. To improve quality of life of the patient, theveterinary team opted for surgical excision of the tumoral ulcerations. Slight claudication in the pelvic limbs was noticedprior to the surgery. Histopathological analyses of the excised nodules verified the existence of malignant mesenchymalneoplasia, which was categorized as peripheral nerve sheath tumor after immunohistochemical examination. Additionalcutaneous tumors emerged after surgical excision, along with increased claudication, edema, and pain in the legs. Completeblood count revealed persistent anemia, lymphopenia, monocytosis, and neutrophilia. Radiographs showed an increasein the number and size of the nodules. Radiography of the limbs showed presence of palisading periosteal reaction, andincreased...

Tumor maligno da bainha de nervo periférico e osteopatia hipertrófica em cadela / Malignant peripheral nerve sheath tumor and hypertrophic osteopathy in a bitch

Background: Malignant peripheral nerve sheath tumors (MPNSTs) are rare, aggressive, relapsing, metastatic cutaneousneoplasms of mesenchymal origin. So far, no account on the association of this disease with hypertrophic osteopathy (HO)in dogs is available in the literature. Current theories on the possible causes of HO suggest that this disease may be triggered by a primary neoplasm as well as by its metastasis. The objective of this work is to report the clinical, cytological,radiographic, histopathological, and immunohistochemical aspects of a dog affected by MPNST and HO.Case: A 13-year-old female mongrel dog was presented with a history of ulcerated nodular lesion on the skin of the flank.Several ulcerated and non-ulcerated tumors were observed on the thorax, neck, and head at the physical exam. Cytological examination of the nodules revealed presence of mesenchymal cells with a malignant aspect. Complete blood countrevealed anemia. There were no alterations in the biochemical tests performed. Thoracic radiographs showed presence of anodular interstitial pattern in the cranial, medial, and caudal lobes of the lungs. To improve quality of life of the patient, theveterinary team opted for surgical excision of the tumoral ulcerations. Slight claudication in the pelvic limbs was noticedprior to the surgery. Histopathological analyses of the excised nodules verified the existence of malignant mesenchymalneoplasia, which was categorized as peripheral nerve sheath tumor after immunohistochemical examination. Additionalcutaneous tumors emerged after surgical excision, along with increased claudication, edema, and pain in the legs. Completeblood count revealed persistent anemia, lymphopenia, monocytosis, and neutrophilia. Radiographs showed an increasein the number and size of the nodules. Radiography of the limbs showed presence of palisading periosteal reaction, andincreased...(AU)

Congenital hepatic fibrosis associated with ascites in a nellore calf / Fibrose hepática congênita associada à ascite em um bezerro nelore

Congenital hepatic fibrosis (CHF) is an autosomal recessive malformation characterized by a variable degree of fibrosis and bile duct proliferation, mainly described in people and rarely reported in bovine European breeds. In addition to liver fibrosis, this syndrome has been associated with ascites and subcutaneous edema in calves. This paper described the pathological findings of the first report of CHF in a Nelore bovine fetus. A stillborn calf was removed by cesarean section because of dystocia. At necropsy, characteristic changes of CHF were observed, such as a large increase in abdominal volume associated with hepatic fibrosis and marked subcutaneous edema. Histological examination of liver revealed periportal and port-portal islands of fibrosis separating the parenchyma into nodules of variable sizes and containing numerous abnormally shaped bile ducts. The CHF should be considered in the differential diagnosis in young calves that present with ascites.(AU)

A fibrose hepática congênita (FHC) é uma malformação autossômica recessiva, caracterizada por um variável grau de fibrose e proliferação de ductos biliares, descrita principalmente em pessoas, e raramente relatada em bovinos de raças europeias. Além da fibrose hepática em bezerros, esta síndrome tem sido associada à ascite e edema subcutâneo. O presente trabalho apresenta os achados anatomopatológicos do primeiro relato de FHC em um feto bovino da raça nelore. O bezerro natimorto foi retirado por meio de cesariana devido à distocia. Na necropsia foram verificadas alterações características da FHC, como grande aumento de volume abdominal associado à fibrose hepática e marcado edema subcutâneo. O exame histológico do fígado revelou ilhas de fibrose periportal e porto-portal, separando o parênquima em nódulos de tamanhos variáveis e contendo numerosos ductos biliares irregulares de tamanhos anormais.(AU)

Carcinoma écrino e apócrino em cães / Eccrine and apocrine carcinoma in dogs

Background: Sweat gland carcinomas divide into eccrine, apocrine, mixed origin (eccrine and apocrine). Eccrine carcinoma(EC) is a rare malignant neoplasm of the sweat glands that can affect dogs, cats, and humans. EC can present itself as asolitary swelling in the pads, digits, or distal limbs. EC is more common in elder animals, and exhibits no predispositionaccording to breed. In humans, EC is more frequent in the head and neck, and is more likely to occur in mid-aged people;metastases can develop in any site of the body. A diagnosis of this type of tumor can be determined by histopathologicalexamination. Apocrine carcinomas occur most frequently in the axillary areas even though they may occur in other regionsof the body, and affect mainly elder animals.Case: A 13-year-old male mongrel dog with a history of presence of smooth reddish infiltrative nodule in the skin of thethorax, but with no history of progression, was examined. After running complementary tests, a fragment of the skin onthe thorax was taken for biopsy. The second animal was an 8-year-old female Golden Retriever, which was presented witha history of presence of a nodule on the right digital pad. After running complementary tests, a fragment of this nodulewas collected. In both cases, the excised fragments were placed in 10% buffered formalin and routinely processed forthe preparation of histological slides, which were stained with hematoxylin and eosin, and subjected to histopathologicalevaluation. Light microscopy analysis revealed, in both cases, the presence of a poorly delimited, non-encapsulated massinfiltrating the muscle and adipose tissue. Necrotic areas, and presence of eosinophilic material in the nucleus were observed.Additionally, the samples from both cases were subjected to immunohistochemical staining for cytokeratin (CK Pan).Discussion: A definitive diagnosis of sweat gland carcinoma...

Carcinoma écrino e apócrino em cães / Eccrine and apocrine carcinoma in dogs

Background: Sweat gland carcinomas divide into eccrine, apocrine, mixed origin (eccrine and apocrine). Eccrine carcinoma(EC) is a rare malignant neoplasm of the sweat glands that can affect dogs, cats, and humans. EC can present itself as asolitary swelling in the pads, digits, or distal limbs. EC is more common in elder animals, and exhibits no predispositionaccording to breed. In humans, EC is more frequent in the head and neck, and is more likely to occur in mid-aged people;metastases can develop in any site of the body. A diagnosis of this type of tumor can be determined by histopathologicalexamination. Apocrine carcinomas occur most frequently in the axillary areas even though they may occur in other regionsof the body, and affect mainly elder animals.Case: A 13-year-old male mongrel dog with a history of presence of smooth reddish infiltrative nodule in the skin of thethorax, but with no history of progression, was examined. After running complementary tests, a fragment of the skin onthe thorax was taken for biopsy. The second animal was an 8-year-old female Golden Retriever, which was presented witha history of presence of a nodule on the right digital pad. After running complementary tests, a fragment of this nodulewas collected. In both cases, the excised fragments were placed in 10% buffered formalin and routinely processed forthe preparation of histological slides, which were stained with hematoxylin and eosin, and subjected to histopathologicalevaluation. Light microscopy analysis revealed, in both cases, the presence of a poorly delimited, non-encapsulated massinfiltrating the muscle and adipose tissue. Necrotic areas, and presence of eosinophilic material in the nucleus were observed.Additionally, the samples from both cases were subjected to immunohistochemical staining for cytokeratin (CK Pan).Discussion: A definitive diagnosis of sweat gland carcinoma...(AU)

Behavioral assessment of shelter dogs submitted to different methods of environmental enrichment / Avaliação comportamental de cães de abrigo submetidos a diferentes métodos de enriquecimento ambiental

Environmental enrichment is a dynamic process consisting of a set of activities designed to meet the ethological and psychological needs of animals. It stimulates the natural behavior of each animal species improving the well-being of the individual and avoiding the development of stereotyped behaviors. The present study aimed to assess the potential benefits that four different types of environmental enrichment would bring to the quality of life of shelter dogs. Twenty dogs were observed for 6 hours daily for 5 consecutive days in the first week in order to assess and document their behavior patterns in an experimental kennel. Between the second to the fourth week, 3 forms of game and 1 type of food enrichment were used in the first 4 days of each week. On the fifth day of each week, behavioral patterns were recorded and later compiled and analyzed according to the Tukey test. Statistical analysis showed significant differences in behaviors associated with lying down, standing up, and licking. Based on our findings, we concluded that the use of environmental enrichment methods through different types of games and toys in shelters decreased signs of depression and stereotyped behavior of kennelled dogs. Results of the present study showed that these tools may help improve life quality of these animals.(AU)

O enriquecimento ambiental é um processo dinâmico que consiste em um conjunto de atividades com a finalidade de atender às necessidades etológicas e psicológicas dos animais, estimulando os comportamentos naturais de cada espécie, melhorando o bem estar e evitando comportamentos estereotipados. O objetivo deste trabalho foi observar o benefício que quatro diferentes formas de enriquecimento ambiental trariam para melhorar a qualidade de vida de cães de abrigo. Vinte cães foram observados durante 6 horas diárias por cinco dias consecutivos na primeira semana, com a finalidade de se obter o padrão de comportamento no ambiente estéril do abrigo. Da segunda à quarta semana foram aplicadas três formas de brincadeiras e uma forma de enriquecimento alimentar nos primeiros quatro dias de cada semana. No quinto dia de cada semana os padrões de comportamento foram registrados e, posteriormente, compilados e analisados pelo teste de Tukey. A análise estatística demonstrou diferença significativa nos comportamentos de deitar, de ficar em pé e de lamber-se. Conclui-se que a aplicação do enriquecimento ambiental, por meio de diferentes formas de brincadeiras, empregado em abrigo para cães, diminuiu os sinais de depressão e os comportamentos estereotipados, demonstrando ser uma ótima ferramenta para aumentar a qualidade de vida destes animais.(AU)

Cytological, histopathological, histochemical, and immunohistochemical findings of multiple cutaneous nodules in a bovine / Achados citológicos, histopatológicos, histoquímicos e imuno-histoquímicos de múltiplas nodulações cutâneas em um bovino

This case study describes the cytological and histopathological findings of cutaneous masses in a bovine, including a peripheral nerve sheath tumor (PNST), vaccine-associated granulomatous inflammation, and eosinophilic inflammation due to parasitosis. A six-year-old undefined cow (SRD) presented with heterogeneous cutaneous lesions including multiple nodules in the left paralumbar fossa, bilaterally at the withers, and scattered along the dorsum, limbs and near the tail; some lesions were associated with ticks. Cytology of these nodules showed benign mesenchymal neoplasia (paralumbar fossa), granulomatous and pyogranulomatous inflammation (withers) and keratin (dorsum). Histopathology, in this order, confirmed PNST, post-vaccination granuloma, and eosinophilic dermatitis. A peripheral nerve sheath tumor was suspected based on the histological findings, showing a well-delineated proliferation of fusiform cells arranged in plexiform structures, which appeared red by Masson's Trichrome stain. The diagnosis was confirmed by immunohistochemistry (anti-S100 antibody). Vaccine reaction often occurs in cattle, and cytological examination is sufficient to determine the inflammatory process. Eosinophilic dermatitis is usually accompanied by perivascular inflammation and reflects the exfoliative process by the oral apparatus of the parasite.

Descrevem-se os achados citológicos e histopatológicos do tumor de bainha de nervo periférico (TBNP), da reação vacinal e da inflamação eosinofílica decorrente dapicada de carrapatoem um bovino. Uma vaca sem raça definida (SRD) de seis anos de idade foi apresentada com diferentes lesões cutâneasnodulares localizadas na fossa paralombar esquerda, bilateralmente na cernelha e dispersos no dorso, membros e próximo à cauda, por vezes associado a carrapatos. Realizou-se citologia e biópsia desses nódulos. Na citologia verificou-se neoplasia mesenquimal benigna (fossa paralombar), inflamação granulomatosa e piogranulomatosa (cernelha) e ceratina (dorso). Na histopatologia, confirmou-se que esses nódulos correspondiam, nessa ordem, a tumor de bainha de nervo periférico, granuloma vacinal e dermatite eosinofílica. O diagnóstico do TBNP foi estabelecido com base nos achados histológicos, que caracterizaram-se por uma proliferação bem delimitada de células fusiformes arranjadas em estruturas plexiformes, corados em vermelho pelo Tricômico de Masson, e confirmado por imuno-histoquímica (anticorpo anti-S100). A reação vacinal ocorre frequentemente em bovinos e o exame citológico é suficiente para determinação do processo inflamatório. Dermatite eosinofílica em geral é acompanhada de inflamação perivascular e perianexal e reflete a ação esfoliativa do

Leiomioma de bexiga em um cão / Bladder leiomyoma in a male dog

Background: In dogs, neoplasms of the urinary bladder are uncommon; among urinary bladder tumors, transitional cell carcinoma is the most frequent type. Urinary bladder leiomyomas are rare mesenchymal tumors whose etiology is associated with urinary retention and exposure to carcinogens. Diagnosis of this neoplasm can be determined by histopathological analysis, and treatment is surgical. The aim of this report is to describe a case of leiomyoma in the urinary bladder of a dog.Case: A 10-year-old male mongrel dog was examined at the Veterinary Hospital of Federal University of Paraíba, where a mass in the urinary bladder was identified, and was estimated to have been developing over the course of a month. Hematuria, congested ocular mucosa, and engorged episcleral vessels were observed during the physical examination. Ultrasonographic examination confirmed distension of the urinary bladder, which exhibited anechoic content and echogenic sediment. A neoplasm measuring 8 x 3.39 cm was detected in the bladder wall. This neoplasm had mixed echogenicity, heterogeneous echotexture, and well-defined borders. Color Doppler ultrasonography allowed observation of vascularization inside the mass. The animal was subjected to cystotomy to excise the mass, which was slightly adhered to the inner wall of the bladder. After this procedure, the excised specimen was submitted for histopathological analysis. Macroscopic examination revealed that the mass was firm, lobulated, nodular, and resistant to cutting. The sample was fixed in 10% formalin; the fragments were processed and stained with hematoxylin and eosin (HE) or Masson’s trichrome (MT) for analysis by optical microscopy. The histopathological examination revealed that the mass was encapsulated, had well-delimited borders composed by bundles of elongated cells with no atypical characteristics. These cells exhibited a slightly eosinophilic cytoplasm that contained moderate to abundant fusiform nuclei.[...]

Leiomioma de bexiga em um cão / Bladder leiomyoma in a male dog

Background: In dogs, neoplasms of the urinary bladder are uncommon; among urinary bladder tumors, transitional cell carcinoma is the most frequent type. Urinary bladder leiomyomas are rare mesenchymal tumors whose etiology is associated with urinary retention and exposure to carcinogens. Diagnosis of this neoplasm can be determined by histopathological analysis, and treatment is surgical. The aim of this report is to describe a case of leiomyoma in the urinary bladder of a dog.Case: A 10-year-old male mongrel dog was examined at the Veterinary Hospital of Federal University of Paraíba, where a mass in the urinary bladder was identified, and was estimated to have been developing over the course of a month. Hematuria, congested ocular mucosa, and engorged episcleral vessels were observed during the physical examination. Ultrasonographic examination confirmed distension of the urinary bladder, which exhibited anechoic content and echogenic sediment. A neoplasm measuring 8 x 3.39 cm was detected in the bladder wall. This neoplasm had mixed echogenicity, heterogeneous echotexture, and well-defined borders. Color Doppler ultrasonography allowed observation of vascularization inside the mass. The animal was subjected to cystotomy to excise the mass, which was slightly adhered to the inner wall of the bladder. After this procedure, the excised specimen was submitted for histopathological analysis. Macroscopic examination revealed that the mass was firm, lobulated, nodular, and resistant to cutting. The sample was fixed in 10% formalin; the fragments were processed and stained with hematoxylin and eosin (HE) or Massons trichrome (MT) for analysis by optical microscopy. The histopathological examination revealed that the mass was encapsulated, had well-delimited borders composed by bundles of elongated cells with no atypical characteristics. These cells exhibited a slightly eosinophilic cytoplasm that contained moderate to abundant fusiform nuclei.[...](AU)

Sialoadenite e hiperplasia gengival induzidas por desgaste dentário irregular em equino: relato de caso / Sialoadenite and gengival hyperplasia induced by irregular dental wear in equine: case report / Sialoadenita e hiperplasia gengival inducida por desgaste dental irregular en equinos: reporte de un caso

A rotina no cuidado dos dentes é essencial para a saúde dos equinos. Exames periódicos e manutenção regular são procedimentos extremamente necessários devido à alteração na dieta e padrões alimentares dos equinos que ocorreram principalmente com o advento da domesticação e confinamento desses animais. Uma das consequências dessa saúde bucal acometida são as hiperplasias gengivais. Hiperplasia gengival é o aumento não inflamatório da gengiva associada ao desgaste da arcada dentária, levando a excessivos traumas. De forma secundária, pode-se levar a uma lesão nas glândulas salivares, conhecida como sialoadenite. O objetivo desse trabalho é relatar o caso atendido no Hospital Veterinário de Grandes Animais-UFPB, equino, Quarto de Milha, fêmea, 7 anos. Durante a anamnese, o proprietário relatou o crescimento progressivo de uma massa localizada na cavidade oral. Após a avaliação física o paciente foi encaminhado para a cirurgia, onde se retirou o tecido acometido encaminhando o fragmento o histopatológico, confirmando a presença de hiperplasia gengival e sialoadenite. Essas entidades patológicas são pouco frequentes, clinicamente pode ser confundida com uma neoplasia. Por isso, é necessário o conhecimento das alterações possíveis das glândulas salivares bem como dos recursos de exames complementares disponíveis para o diagnóstico destas, são imprescindíveis, tendo em vista que existem afecções com a apresentação clínica bastante similar.

Routine teeth care is essential for the health of horses. Periodic examinations and regular maintenance are extremely necessary procedures due to changes in diet and eating patterns of horses that occurred mainly with the advent of domestication and confinement ofthese animais. One of the consequences of this affected oral health is the gingival hyperplasias. Gingival hyperplasia is the non inflammatory increase of the gum associated with tooth artery wear, leading to excessive trauma. Secondarily, it can lead to an injury to the salivary glands, known as sialoadenitis. The objective of this work is to report the case attended at the Veterinary Hospital of Large Animals-UFPB, equine, Quarter of a Mile, female, 7 years. During the anamnesis, the owner reported the progressive growth of a mass located in the oral cavity. After the physical evaluation, the patient was referred to surgery, where the affected tissue was removed and the histopathological fragment was removed, confirming the presence of gingival hyperplasia and sialoadenitis. These pathological entities are uncommon, clinically can be confused with a neoplasia. Therefore, it is necessary to know the possible alterations of the salivary glands as well as the resources of complementary tests available for the diagnosis of these, are essential, considering that there are affections with the very similar clinical presentation.

La rutina en el cuidado de los dientes es esencial para la salud de los equinos. Exámenes periódicos y mantenimiento regular son procedimientos extremadamente necesarios debido a la alteración en la dieta y patrones alimentarios de los equinos que ocurrieron principalmente con el advenimiento de la domesticación y confinamiento de esos animales. Una de las consecuencias de esta salud bucal acometida son las hiperplasias gingivales. Hiperplasia gingival es el aumento no inflamatorio de la encía asociada ai desgaste de la arcada dental, llevando a excesivos traumas. De forma secundaria, se puede llevar a una lesión en las glándulas salivares, conocida como sialoadenitis. El objetivo de este trabajo es relatar el caso atendido en el Hospital Veterinario de Grandes Animales-UFPB, equino, Cuarto de Milla, hembra, 7 anos. Durante la anamnesis, el propietario relató el crecimiento progresivo de una masa localizada en la cavidade oral. Después de la evaluación física el paciente fue encaminado a la cirugía, donde se retiró el tejido acometido encaminando el fragmento el histopatológico, confirmando la presencia de hiperplasia gingival y sialoadenitis. Estas patologías son poco frecuentes, clínicamente puede confundir se con una neoplasia. Por eso, es necesario el conocimiento de las alteraciones posibles de las glándulas salivares así como de los recursos de exámenes complementarios disponibles para el diagnóstico de estas, son imprescindibles, teniendo en vista que existen afecciones con la presentación clínica bastante similar.

Sialoadenite e hiperplasia gengival induzidas por desgaste dentário irregular em equino: relato de caso / Sialoadenite and gengival hyperplasia induced by irregular dental wear in equine: case report / Sialoadenita e hiperplasia gengival inducida por desgaste dental irregular en equinos: reporte de un caso

A rotina no cuidado dos dentes é essencial para a saúde dos equinos. Exames periódicos e manutenção regular são procedimentos extremamente necessários devido à alteração na dieta e padrões alimentares dos equinos que ocorreram principalmente com o advento da domesticação e confinamento desses animais. Uma das consequências dessa saúde bucal acometida são as hiperplasias gengivais. Hiperplasia gengival é o aumento não inflamatório da gengiva associada ao desgaste da arcada dentária, levando a excessivos traumas. De forma secundária, pode-se levar a uma lesão nas glândulas salivares, conhecida como sialoadenite. O objetivo desse trabalho é relatar o caso atendido no Hospital Veterinário de Grandes Animais-UFPB, equino, Quarto de Milha, fêmea, 7 anos. Durante a anamnese, o proprietário relatou o crescimento progressivo de uma massa localizada na cavidade oral. Após a avaliação física o paciente foi encaminhado para a cirurgia, onde se retirou o tecido acometido encaminhando o fragmento o histopatológico, confirmando a presença de hiperplasia gengival e sialoadenite. Essas entidades patológicas são pouco frequentes, clinicamente pode ser confundida com uma neoplasia. Por isso, é necessário o conhecimento das alterações possíveis das glândulas salivares bem como dos recursos de exames complementares disponíveis para o diagnóstico destas, são imprescindíveis, tendo em vista que existem afecções com a apresentação clínica bastante similar.(AU)

Routine teeth care is essential for the health of horses. Periodic examinations and regular maintenance are extremely necessary procedures due to changes in diet and eating patterns of horses that occurred mainly with the advent of domestication and confinement ofthese animais. One of the consequences of this affected oral health is the gingival hyperplasias. Gingival hyperplasia is the non inflammatory increase of the gum associated with tooth artery wear, leading to excessive trauma. Secondarily, it can lead to an injury to the salivary glands, known as sialoadenitis. The objective of this work is to report the case attended at the Veterinary Hospital of Large Animals-UFPB, equine, Quarter of a Mile, female, 7 years. During the anamnesis, the owner reported the progressive growth of a mass located in the oral cavity. After the physical evaluation, the patient was referred to surgery, where the affected tissue was removed and the histopathological fragment was removed, confirming the presence of gingival hyperplasia and sialoadenitis. These pathological entities are uncommon, clinically can be confused with a neoplasia. Therefore, it is necessary to know the possible alterations of the salivary glands as well as the resources of complementary tests available for the diagnosis of these, are essential, considering that there are affections with the very similar clinical presentation.(AU)

La rutina en el cuidado de los dientes es esencial para la salud de los equinos. Exámenes periódicos y mantenimiento regular son procedimientos extremadamente necesarios debido a la alteración en la dieta y patrones alimentarios de los equinos que ocurrieron principalmente con el advenimiento de la domesticación y confinamiento de esos animales. Una de las consecuencias de esta salud bucal acometida son las hiperplasias gingivales. Hiperplasia gingival es el aumento no inflamatorio de la encía asociada ai desgaste de la arcada dental, llevando a excesivos traumas. De forma secundaria, se puede llevar a una lesión en las glándulas salivares, conocida como sialoadenitis. El objetivo de este trabajo es relatar el caso atendido en el Hospital Veterinario de Grandes Animales-UFPB, equino, Cuarto de Milla, hembra, 7 anos. Durante la anamnesis, el propietario relató el crecimiento progresivo de una masa localizada en la cavidade oral. Después de la evaluación física el paciente fue encaminado a la cirugía, donde se retiró el tejido acometido encaminando el fragmento el histopatológico, confirmando la presencia de hiperplasia gingival y sialoadenitis. Estas patologías son poco frecuentes, clínicamente puede confundir se con una neoplasia. Por eso, es necesario el conocimiento de las alteraciones posibles de las glándulas salivares así como de los recursos de exámenes complementarios disponibles para el diagnóstico de estas, son imprescindibles, teniendo en vista que existen afecciones con la presentación clínica bastante similar.(AU)

Cytological, histopathological, histochemical, and immunohistochemical findings of multiple cutaneous nodules in a bovine / Achados citológicos, histopatológicos, histoquímicos e imuno-histoquímicos de múltiplas nodulações cutâneas em um bovino

This case study describes the cytological and histopathological findings of cutaneous masses in a bovine, including a peripheral nerve sheath tumor (PNST), vaccine-associated granulomatous inflammation, and eosinophilic inflammation due to parasitosis. A six-year-old undefined cow (SRD) presented with heterogeneous cutaneous lesions including multiple nodules in the left paralumbar fossa, bilaterally at the withers, and scattered along the dorsum, limbs and near the tail; some lesions were associated with ticks. Cytology of these nodules showed benign mesenchymal neoplasia (paralumbar fossa), granulomatous and pyogranulomatous inflammation (withers) and keratin (dorsum). Histopathology, in this order, confirmed PNST, post-vaccination granuloma, and eosinophilic dermatitis. A peripheral nerve sheath tumor was suspected based on the histological findings, showing a well-delineated proliferation of fusiform cells arranged in plexiform structures, which appeared red by Masson's Trichrome stain. The diagnosis was confirmed by immunohistochemistry (anti-S100 antibody). Vaccine reaction often occurs in cattle, and cytological examination is sufficient to determine the inflammatory process. Eosinophilic dermatitis is usually accompanied by perivascular inflammation and reflects the exfoliative process by the oral apparatus of the parasite.

Descrevem-se os achados citológicos e histopatológicos do tumor de bainha de nervo periférico (TBNP), da reação vacinal e da inflamação eosinofílica decorrente dapicada de carrapatoem um bovino. Uma vaca sem raça definida (SRD) de seis anos de idade foi apresentada com diferentes lesões cutâneasnodulares localizadas na fossa paralombar esquerda, bilateralmente na cernelha e dispersos no dorso, membros e próximo à cauda, por vezes associado a carrapatos. Realizou-se citologia e biópsia desses nódulos. Na citologia verificou-se neoplasia mesenquimal benigna (fossa paralombar), inflamação granulomatosa e piogranulomatosa (cernelha) e ceratina (dorso). Na histopatologia, confirmou-se que esses nódulos correspondiam, nessa ordem, a tumor de bainha de nervo periférico, granuloma vacinal e dermatite eosinofílica. O diagnóstico do TBNP foi estabelecido com base nos achados histológicos, que caracterizaram-se por uma proliferação bem delimitada de células fusiformes arranjadas em estruturas plexiformes, corados em vermelho pelo Tricômico de Masson, e confirmado por imuno-histoquímica (anticorpo anti-S100). A reação vacinal ocorre frequentemente em bovinos e o exame citológico é suficiente para determinação do processo inflamatório. Dermatite eosinofílica em geral é acompanhada de inflamação perivascular e perianexal e reflete a ação esfoliativa do

Cytological, histopathological, histochemical, and immunohistochemical findings of multiple cutaneous nodules in a bovine / Achados citológicos, histopatológicos, histoquímicos e imuno-histoquímicos de múltiplas nodulações cutâneas em um bovino

This case study describes the cytological and histopathological findings of cutaneous masses in a bovine, including a peripheral nerve sheath tumor (PNST), vaccine-associated granulomatous inflammation, and eosinophilic inflammation due to parasitosis. A six-year-old undefined cow (SRD) presented with heterogeneous cutaneous lesions including multiple nodules in the left paralumbar fossa, bilaterally at the withers, and scattered along the dorsum, limbs and near the tail; some lesions were associated with ticks. Cytology of these nodules showed benign mesenchymal neoplasia (paralumbar fossa), granulomatous and pyogranulomatous inflammation (withers) and keratin (dorsum). Histopathology, in this order, confirmed PNST, post-vaccination granuloma, and eosinophilic dermatitis. A peripheral nerve sheath tumor was suspected based on the histological findings, showing a well-delineated proliferation of fusiform cells arranged in plexiform structures, which appeared red by Masson's Trichrome stain. The diagnosis was confirmed by immunohistochemistry (anti-S100 antibody). Vaccine reaction often occurs in cattle, and cytological examination is sufficient to determine the inflammatory process. Eosinophilic dermatitis is usually accompanied by perivascular inflammation and reflects the exfoliative process by the oral apparatus of the parasite.

Descrevem-se os achados citológicos e histopatológicos do tumor de bainha de nervo periférico (TBNP), da reação vacinal e da inflamação eosinofílica decorrente dapicada de carrapatoem um bovino. Uma vaca sem raça definida (SRD) de seis anos de idade foi apresentada com diferentes lesões cutâneasnodulares localizadas na fossa paralombar esquerda, bilateralmente na cernelha e dispersos no dorso, membros e próximo à cauda, por vezes associado a carrapatos. Realizou-se citologia e biópsia desses nódulos. Na citologia verificou-se neoplasia mesenquimal benigna (fossa paralombar), inflamação granulomatosa e piogranulomatosa (cernelha) e ceratina (dorso). Na histopatologia, confirmou-se que esses nódulos correspondiam, nessa ordem, a tumor de bainha de nervo periférico, granuloma vacinal e dermatite eosinofílica. O diagnóstico do TBNP foi estabelecido com base nos achados histológicos, que caracterizaram-se por uma proliferação bem delimitada de células fusiformes arranjadas em estruturas plexiformes, corados em vermelho pelo Tricômico de Masson, e confirmado por imuno-histoquímica (anticorpo anti-S100). A reação vacinal ocorre frequentemente em bovinos e o exame citológico é suficiente para determinação do processo inflamatório. Dermatite eosinofílica em geral é acompanhada de inflamação perivascular e perianexal e reflete a ação esfoliativa do