Hemangiossarcoma associado a quimiodectoma em cadela Pit Bull idosa / Hemangiosarcoma associated with chemodectoma in an old Pit Bull bitch

Background: The prevalence of neoplasms in domestic animals has been augmenting over the years. Hemangiosarcoma, which most frequently affects large breed dogs, is a neoplasm with high metastatic power and corresponds to 5% of malignant neoplasms. Chemodectoma, a neoplasm that can have malignant or benign behavior, is uncommon, corresponding to less than 8% of all cardiac tumors, and originates from cardiac chemoreceptor cells and involves mainly the aortic and carotid bodies. The aim of this study is to describe the case of an elderly Pit Bull dog with hepatic hemangiosarcoma and chemodectoma associated with four other different tumors: hemangioma, papilloma, mastocitoma and melanoma. Case: A 14-year-old female Pit Bull, castrated, was presented to Veterinary Clinic of the Federal University of Santa Catarina (UFSC), Curitibanos Campus, Brazil. The owner referred apathy, hyporexia, and increased abdominal volume for two weeks. Physical examination showed emaciation and abdominal effusion. Abdominocentesis was performed, three liters of serosanguineous fluid was drained and a sample was sent for analysis. Complementary tests were requested and showed mild hypoalbuminemia, normocytic normochromic anemia, and lymphopenia. The ultrasound examination revealed thickening of vessels and hepatomegaly, in addition to the presence of an oval structure containing hyperechogenic cavitations. Diagnostic exploratory laparotomy was indicated, but the owner refused. Drug therapy was prescribed in a palliative manner and, during the clinical follow-up period, two abdominocentesis procedures and one thoracentesis procedure were performed, both resulting in simple transudate. Finally, the patient developed severe apathy, edema in all limbs, and died at home. Necroscopic examination was done and revealed hemoperitoneum and hemothorax...

Hemangiossarcoma associado a quimiodectoma em cadela Pit Bull idosa / Hemangiosarcoma associated with chemodectoma in an old Pit Bull bitch

Background: The prevalence of neoplasms in domestic animals has been augmenting over the years. Hemangiosarcoma, which most frequently affects large breed dogs, is a neoplasm with high metastatic power and corresponds to 5% of malignant neoplasms. Chemodectoma, a neoplasm that can have malignant or benign behavior, is uncommon, corresponding to less than 8% of all cardiac tumors, and originates from cardiac chemoreceptor cells and involves mainly the aortic and carotid bodies. The aim of this study is to describe the case of an elderly Pit Bull dog with hepatic hemangiosarcoma and chemodectoma associated with four other different tumors: hemangioma, papilloma, mastocitoma and melanoma. Case: A 14-year-old female Pit Bull, castrated, was presented to Veterinary Clinic of the Federal University of Santa Catarina (UFSC), Curitibanos Campus, Brazil. The owner referred apathy, hyporexia, and increased abdominal volume for two weeks. Physical examination showed emaciation and abdominal effusion. Abdominocentesis was performed, three liters of serosanguineous fluid was drained and a sample was sent for analysis. Complementary tests were requested and showed mild hypoalbuminemia, normocytic normochromic anemia, and lymphopenia. The ultrasound examination revealed thickening of vessels and hepatomegaly, in addition to the presence of an oval structure containing hyperechogenic cavitations. Diagnostic exploratory laparotomy was indicated, but the owner refused. Drug therapy was prescribed in a palliative manner and, during the clinical follow-up period, two abdominocentesis procedures and one thoracentesis procedure were performed, both resulting in simple transudate. Finally, the patient developed severe apathy, edema in all limbs, and died at home. Necroscopic examination was done and revealed hemoperitoneum and hemothorax...(AU)

Angioceratoma conjuntival canino: relato de caso / Canine conjunctival angiokeratoma: case report

O angioceratoma é um tumor de origem vascular, semelhante ao hemangioma, que se diferencia deste por alterações histológicas epiteliais. A apresentação ocular do angioceratoma é pouco frequente em cães, sendo mais comum a ocorrência de hemangioma e hemangiossarcoma. Neste relato, é descrito o caso de um cão, macho, da raça Border Collie, que apresentava uma massa localizada, hiperêmica, bem vascularizada e protrusa, na região temporal da conjuntiva bulbar do olho direito (OD). Foi realizado exame oftalmológico completo e ultrassonografia ocular, tendo sido possível observar que a massa não envolvia outras estruturas oculares além da conjuntiva. Dessa forma, foi realizada a conjuntivectomia parcial, e o material foi encaminhado para análise histológica. O exame histopatológico foi conclusivo para um angioceratoma e mostrou que as margens da amostra estavam livres. O procedimento cirúrgico com margem de segurança foi eficiente no tratamento da neoplasia, sem recorrência até o momento do presente relato.(AU)

Angiokeratomas have been described as tumors of vascular origin, similar to hemangioma but with participation of adjacent epithelium and less frequent in dogs. In this case we have reported an adult, male, Border Collie dog presenting a localized and hyperemic mass with protrusion surface and well vascularized region of temporal bulbar conjunctiva of the right eye (OD). Complete ocular examination and ocular ultrasound have revealed no involvement of other ocular structures beyond the conjunctiva. A partial conjuntivectomy was surgically performed, tissue material sent for histological analysis and angiokeratoma diagnosis was accurately made. Surgical procedure with a safety tissue margin has shown adequate treatment efficiency, with no neoplasia recurrence to date.(AU)

Angioceratoma conjuntival canino: relato de caso / Canine conjunctival angiokeratoma: case report

O angioceratoma é um tumor de origem vascular, semelhante ao hemangioma, que se diferencia deste por alterações histológicas epiteliais. A apresentação ocular do angioceratoma é pouco frequente em cães, sendo mais comum a ocorrência de hemangioma e hemangiossarcoma. Neste relato, é descrito o caso de um cão, macho, da raça Border Collie, que apresentava uma massa localizada, hiperêmica, bem vascularizada e protrusa, na região temporal da conjuntiva bulbar do olho direito (OD). Foi realizado exame oftalmológico completo e ultrassonografia ocular, tendo sido possível observar que a massa não envolvia outras estruturas oculares além da conjuntiva. Dessa forma, foi realizada a conjuntivectomia parcial, e o material foi encaminhado para análise histológica. O exame histopatológico foi conclusivo para um angioceratoma e mostrou que as margens da amostra estavam livres. O procedimento cirúrgico com margem de segurança foi eficiente no tratamento da neoplasia, sem recorrência até o momento do presente relato.(AU)

Angiokeratomas have been described as tumors of vascular origin, similar to hemangioma but with participation of adjacent epithelium and less frequent in dogs. In this case we have reported an adult, male, Border Collie dog presenting a localized and hyperemic mass with protrusion surface and well vascularized region of temporal bulbar conjunctiva of the right eye (OD). Complete ocular examination and ocular ultrasound have revealed no involvement of other ocular structures beyond the conjunctiva. A partial conjuntivectomy was surgically performed, tissue material sent for histological analysis and angiokeratoma diagnosis was accurately made. Surgical procedure with a safety tissue margin has shown adequate treatment efficiency, with no neoplasia recurrence to date.(AU)

Hemangioma and myelolipoma in the adrenal gland of a dog / Hemangioma e mielolipoma em glândula adrenal de cão

Background: Endocrine tumors are considered rare in veterinary medicine. Studies suggest that only one or two per cent of these are primary neoplasms of the adrenal glands. Concerning the histological classifi cation of these masses, the most frequently occurring malignant neoplasms in dogs are adenocarcinomas and pheochromocytomas and, among the benign tumors, adenomas are the most common. Although much rarer, hemangiomas, myelolipomas, among others, may also occur. Dogs with this kind of neoplasm could be asyntomatic or show gastrointestinal signs, pain and urinary tract infection. Adrenalectomy is the treatment of choice and could be curative in most cases. This paper reports a case of two concurrent benign, rare adrenal neoplasms in a dog, emphasizing the clinical signs, diagnosis and treatmentCase: An eight-year-old, male castrated Chow-chow, weighting twenty one kilograms, was admitted at the Veterinary Teaching Hospital of the Federal University of Rio Grande do Sul (UFRGS) with a history of intermittent vomiting and diarrhea since it was a puppy. Because of the chronicity and nonspecifi c signs, additional tests were requested. Abdominal ultrasonography showed a round mass, measuring approximately 3.7 cm x 3.2 cm, suggesting a neoplasm. Blood pressure was measured and the mean value was 152 mmHg. Laboratory tests included a complete blood count, albumin (31.62 g/L), ala

Background: Endocrine tumors are considered rare in veterinary medicine. Studies suggest that only one or two per cent of these are primary neoplasms of the adrenal glands. Concerning the histological classifi cation of these masses, the most frequently occurring malignant neoplasms in dogs are adenocarcinomas and pheochromocytomas and, among the benign tumors, adenomas are the most common. Although much rarer, hemangiomas, myelolipomas, among others, may also occur. Dogs with this kind of neoplasm could be asyntomatic or show gastrointestinal signs, pain and urinary tract infection. Adrenalectomy is the treatment of choice and could be curative in most cases. This paper reports a case of two concurrent benign, rare adrenal neoplasms in a dog, emphasizing the clinical signs, diagnosis and treatment.Case: An eight-year-old, male castrated Chow-chow, weighting twenty one kilograms, was admitted at the Veterinary Teaching Hospital of the Federal University of Rio Grande do Sul (UFRGS) with a history of intermittent vomiting and diarrhea since it was a puppy. Because of the chronicity and nonspecifi c signs, additional tests were requested. Abdominal ultrasonography showed a round mass, measuring approximately 3.7 cm x 3.2 cm, suggesting a neoplasm. Blood pressure was measured and the mean value was 152 mmHg. Laboratory tests included a complete blood count, albumin (31.62 g/L), al

Hemangioma e mielolipoma em glândula adrenal de cão / Hemangioma and myelolipoma in the adrenal gland of a dog

Background: Endocrine tumors are considered rare in veterinary medicine. Studies suggest that only one or two per cent of these are primary neoplasms of the adrenal glands. Concerning the histological classification of these masses, the most frequently occurring malignant neoplasms in dogs are adenocarcinomas and pheochromocytomas and, among the benign tumors, adenomas are the most common. Although much rarer, hemangiomas, myelolipomas, among others, may also occur. Dogs with this kind of neoplasm could be asyntomatic or show gastrointestinal signs, pain and urinary tract infection. Adrenalectomy is the treatment of choice and could be curative in most cases. This paper reports a case of two concurrent benign, rare adrenal neoplasms in a dog, emphasizing the clinical signs, diagnosis and treatment. Case: An eight-year-old, male castrated Chow-chow, weighting twenty one kilograms, was admitted at the Veterinary Teaching Hospital of the Federal University of Rio Grande do Sul (UFRGS) with a history of intermittent vomiting and diarrhea since it was a puppy. Because of the chronicity and nonspecific signs, additional tests were requested. Abdominal ultrasonography showed a round mass, measuring approximately 3.7 cm x 3.2 cm, suggesting a neoplasm. Blood pressure was measured and the mean value was 152 mmHg. Laboratory tests included a complete blood count, albumin (31.62 g/L), alanine aminotransferase (26.19 U/L), alkaline phosphatase (64.68 U/L), sodium (147 mmoL), potassium (4.5 mEq/L), fasting blood glucose (60.87 mg/dL), cholesterol (137.64 mg/dL), triglycerides (34.89 mg/dL), amylase (592 U/L), lipase (163 U/L), creatinine (0.67 mg/dL), and parasitologic exam of the feaces, which revealed no significant changes at all. An unilateral adrenalectomy was performed for diagnostic and therapeutic purposes. The patient was anesthetized and was placed in left lateral recumbency. An incision was made along the thirteenth rib, allowing an adequate visualization of the right adrenal. A careful dissection and ligation of vessels was performed, the gland was removed and sent for histopathology. The abdominal cavity was sutured routinely. Histopathological examination disclosed two fragments of benign tumors, namely myelolipoma and hemangioma. The animal had an excellent postoperative recovery, being given antibiotics, analgesics and daily dressings as treatment. In the follow-up reexamination only mucus persisted in the stool, however a diagnostic colonoscopy was not authorized by the owner. Discussion: Adrenalectomy represented both the definitive diagnostic and therapeutic methods of choice, since the growth of these masses could compromise adjacent organs. The open approach is the method used for adrenalectomy in veterinary patients, as opposed to people, where the laparoscopic surgery is generally chosen. In this report, we opted for an right paracostal incision to allow a better exposure and dissection of the adrenal gland in this medium-sized dog. There was no need for supplemental glucocorticoids in the postoperative period because these neoplasms are non-functioning, which represents a contraindication for its use. Therefore, total adrenalectomy was proven effective in the treatment of these two concurrent adrenal neoplasms, as supported by the postoperative course.

Hemangioma primário de córnea: relato de caso / Primary corneal hemangioma: case report

Foi atendido um cão, fêmea, sem raça definida, de 8 anos de idade, com histórico de um tecido avermelhado na superfície do olho esquerdo (OE) com evolução de aproximadamente 1 mês. Ao exame oftálmico não foram observadas outras alterações oculares, exceto a presença da massa, ocupando grande parte da superfície corneana e discreta secreção mucosa. Foi instituída terapia tópica à base de dexametasona sem melhora clínica. Com base nos achados, a suspeita diagnóstica foi de neoplasia corneana sendo realizada ceratectomia lamelar superficial. No pós-operatório, observou-se vascularização leve e opacidade corneana, com visão preservada. O exame histopatológico confirmou o diagnóstico de neoplasia vascular benigna compatível com hemangioma. Houve recidiva após 12 meses e nova cirurgia foi realizada com sucesso. O hemangioma primário de córnea é uma neoplasia rara, e deve ser considerado como diagnóstico diferencial de alterações corneanas não responsivas a tratamento clínico. O caso está sendo acompanhado e não houve recidiva até o presente momento.AU

An 8-year-old dog, female, mixed breed, was presented for evaluation of a reddish tissue on the surface of the left eye (OS) that had been growing for about 1 month. Ophthalmic examination showed no ocular abnormalities, except for the presence of the mass, affecting much of the corneal surface and discrete mucous discharge. Was instituted topical dexamethasone therapy without clinical improvement. . Based on the clinical findings, a diagnosis of corneal neoplasia was suspected. Superficial lamellar keratectomy was performed. Postoperatively, mild corneal opacity and vascularization were noticed, with no visual impairment. Histopathological examination confirmed the diagnosis of benign vascular neoplasm compatible with hemangioma. The neoplasia recurred after 12 months and another surgery was successfully performed. Primary hemangioma of the cornea is a rare neoplasm, and should be considered as differential corneal alterations do not respond to medical treatment. The case is being followed and there was no recurrence to date.AU

Hemangioma primário de córnea: relato de caso / Primary corneal hemangioma: case report

Foi atendido um cão, fêmea, sem raça definida, de 8 anos de idade, com histórico de um tecido avermelhado na superfície do olho esquerdo (OE) com evolução de aproximadamente 1 mês. Ao exame oftálmico não foram observadas outras alterações oculares, exceto a presença da massa, ocupando grande parte da superfície corneana e discreta secreção mucosa. Foi instituída terapia tópica à base de dexametasona sem melhora clínica. Com base nos achados, a suspeita diagnóstica foi de neoplasia corneana sendo realizada ceratectomia lamelar superficial. No pós-operatório, observou-se vascularização leve e opacidade corneana, com visão preservada. O exame histopatológico confirmou o diagnóstico de neoplasia vascular benigna compatível com hemangioma. Houve recidiva após 12 meses e nova cirurgia foi realizada com sucesso. O hemangioma primário de córnea é uma neoplasia rara, e deve ser considerado como diagnóstico diferencial de alterações corneanas não responsivas a tratamento clínico. O caso está sendo acompanhado e não houve recidiva até o presente momento.

An 8-year-old dog, female, mixed breed, was presented for evaluation of a reddish tissue on the surface of the left eye (OS) that had been growing for about 1 month. Ophthalmic examination showed no ocular abnormalities, except for the presence of the mass, affecting much of the corneal surface and discrete mucous discharge. Was instituted topical dexamethasone therapy without clinical improvement. . Based on the clinical findings, a diagnosis of corneal neoplasia was suspected. Superficial lamellar keratectomy was performed. Postoperatively, mild corneal opacity and vascularization were noticed, with no visual impairment. Histopathological examination confirmed the diagnosis of benign vascular neoplasm compatible with hemangioma. The neoplasia recurred after 12 months and another surgery was successfully performed. Primary hemangioma of the cornea is a rare neoplasm, and should be considered as differential corneal alterations do not respond to medical treatment. The case is being followed and there was no recurrence to date.

Estudo retrospectivo de 18 neoplasmas do endotélio vascular emolhos de cães da cidade de Curitiba, Paraná / Retrospective evaluation of 18 ocular vascular endothelial neoplasms in dogs from Curitiba, Paraná

Nos cães, os neoplasmas oculares com origem no endotélio vascular são o hemangioma e o hemangiossarcoma.Neste estudo investigou-se o comportamento epidemiológico de 18 casos de neoplasmas do endotélio vascular(cinco hemangiomas e 13 hemangiossarcomas) em olhos de 17 cães da cidade de Curitiba, Paraná. A maioria dosachados corrobora os dados da literatura, excetuando-se a prevalência racial previamente descrita, por se tratardo primeiro estudo brasileiro sobre o assunto. Neoplasmas em olhos de cães apresentam prognósticos diferentes,de acordo com o tipo celular, sem relação diagnóstica ou prognóstica com seu tamanho, e sempre devemser encaminhados para análise histopatológica, embasando o tratamento específico e estudos epidemiológicos.(AU)

In dogs, the ocular vascular endothelial neoplasms are hemangioma and hemangiosarcoma. There wasinvestigated the epidemiological behavior of 18 ocular vascular endothelial neoplasms (five hemangiomasand 13 hemangiosarcomas) in 17 dogs from Curitiba, Paraná, Brazil. Our main results corroboratethe literature, with the exception of the previously described racial prevalence, because this is the firststudy performed in Brazil about these tumors. Ocular tumors in dogs have different prognoses, accordingto the cell type, and do not show diagnostic or prognostic relation with their size. They shouldalways be sent to histopathological analysis, supporting specific treatment and epidemiological studies.(AU)

Estudo retrospectivo de 18 neoplasmas do endotélio vascular emolhos de cães da cidade de Curitiba, Paraná / Retrospective evaluation of 18 ocular vascular endothelial neoplasms in dogs from Curitiba, Paraná

Nos cães, os neoplasmas oculares com origem no endotélio vascular são o hemangioma e o hemangiossarcoma.Neste estudo investigou-se o comportamento epidemiológico de 18 casos de neoplasmas do endotélio vascular(cinco hemangiomas e 13 hemangiossarcomas) em olhos de 17 cães da cidade de Curitiba, Paraná. A maioria dosachados corrobora os dados da literatura, excetuando-se a prevalência racial previamente descrita, por se tratardo primeiro estudo brasileiro sobre o assunto. Neoplasmas em olhos de cães apresentam prognósticos diferentes,de acordo com o tipo celular, sem relação diagnóstica ou prognóstica com seu tamanho, e sempre devemser encaminhados para análise histopatológica, embasando o tratamento específico e estudos epidemiológicos.

In dogs, the ocular vascular endothelial neoplasms are hemangioma and hemangiosarcoma. There wasinvestigated the epidemiological behavior of 18 ocular vascular endothelial neoplasms (five hemangiomasand 13 hemangiosarcomas) in 17 dogs from Curitiba, Paraná, Brazil. Our main results corroboratethe literature, with the exception of the previously described racial prevalence, because this is the firststudy performed in Brazil about these tumors. Ocular tumors in dogs have different prognoses, accordingto the cell type, and do not show diagnostic or prognostic relation with their size. They shouldalways be sent to histopathological analysis, supporting specific treatment and epidemiological studies.

Hemangioma cutâneo canino / Canine cutaneous hemangioma

Os hemangiomas são tumores benignos não invasivos e nem metastáticos, embora alguns autores acreditem que a transformação maligna possa ocorrer em alguns casos multicêntricos e nos tumores induzidos pela luz do sol. O objetivo do trabalho foi relatar um caso de hemangioma cutâneo com presença de calcinose circunscrita, em uma cadela da raça rottweiler, de um ano de idade, atendida no Hospital Veterinário da Faculdade de Veterinária, Moçambique. O tratamento foi cirúrgico, sendo o hemograma e bioquímica sanguínea, exames complementares não conclusivos para um diagnósticodefi nitivo, que foi obtido pela histopatologia. (AU)

Hemangioma is a benign tumor or metastatic non-invasive tumor, although some authors believe that malignant transformation may occur in some cases and in multicentric tumors induced by the sun light. This study aims to report a case of cutaneous hemangioma with the presence of circumscribed calcinosis in a rottweiler bitch, one year old, attended at the Veterinary Hospital, Veterinary College, Mozambique. The treatment was surgical and the hemogram and blood biochemistry were inconclusive for a defi nitive diagnosis, obtained only by histopathology. (AU)

Hemangioma cutâneo canino / Canine cutaneous hemangioma

Os hemangiomas são tumores benignos não invasivos e nem metastáticos, embora alguns autores acreditem que a transformação maligna possa ocorrer em alguns casos multicêntricos e nos tumores induzidos pela luz do sol. O objetivo do trabalho foi relatar um caso de hemangioma cutâneo com presença de calcinose circunscrita, em uma cadela da raça rottweiler, de um ano de idade, atendida no Hospital Veterinário da Faculdade de Veterinária, Moçambique. O tratamento foi cirúrgico, sendo o hemograma e bioquímica sanguínea, exames complementares não conclusivos para um diagnósticodefi nitivo, que foi obtido pela histopatologia.

Hemangioma is a benign tumor or metastatic non-invasive tumor, although some authors believe that malignant transformation may occur in some cases and in multicentric tumors induced by the sun light. This study aims to report a case of cutaneous hemangioma with the presence of circumscribed calcinosis in a rottweiler bitch, one year old, attended at the Veterinary Hospital, Veterinary College, Mozambique. The treatment was surgical and the hemogram and blood biochemistry were inconclusive for a defi nitive diagnosis, obtained only by histopathology.

Hemangioma and myelolipoma in the adrenal gland of a dog / Hemangioma e mielolipoma em glândula adrenal de cão

Background: Endocrine tumors are considered rare in veterinary medicine. Studies suggest that only one or two per cent of these are primary neoplasms of the adrenal glands. Concerning the histological classifi cation of these masses, the most frequently occurring malignant neoplasms in dogs are adenocarcinomas and pheochromocytomas and, among the benign tumors, adenomas are the most common. Although much rarer, hemangiomas, myelolipomas, among others, may also occur. Dogs with this kind of neoplasm could be asyntomatic or show gastrointestinal signs, pain and urinary tract infection. Adrenalectomy is the treatment of choice and could be curative in most cases. This paper reports a case of two concurrent benign, rare adrenal neoplasms in a dog, emphasizing the clinical signs, diagnosis and treatmentCase: An eight-year-old, male castrated Chow-chow, weighting twenty one kilograms, was admitted at the Veterinary Teaching Hospital of the Federal University of Rio Grande do Sul (UFRGS) with a history of intermittent vomiting and diarrhea since it was a puppy. Because of the chronicity and nonspecifi c signs, additional tests were requested. Abdominal ultrasonography showed a round mass, measuring approximately 3.7 cm x 3.2 cm, suggesting a neoplasm. Blood pressure was measured and the mean value was 152 mmHg. Laboratory tests included a complete blood count, albumin (31.62 g/L), ala

Background: Endocrine tumors are considered rare in veterinary medicine. Studies suggest that only one or two per cent of these are primary neoplasms of the adrenal glands. Concerning the histological classifi cation of these masses, the most frequently occurring malignant neoplasms in dogs are adenocarcinomas and pheochromocytomas and, among the benign tumors, adenomas are the most common. Although much rarer, hemangiomas, myelolipomas, among others, may also occur. Dogs with this kind of neoplasm could be asyntomatic or show gastrointestinal signs, pain and urinary tract infection. Adrenalectomy is the treatment of choice and could be curative in most cases. This paper reports a case of two concurrent benign, rare adrenal neoplasms in a dog, emphasizing the clinical signs, diagnosis and treatment.Case: An eight-year-old, male castrated Chow-chow, weighting twenty one kilograms, was admitted at the Veterinary Teaching Hospital of the Federal University of Rio Grande do Sul (UFRGS) with a history of intermittent vomiting and diarrhea since it was a puppy. Because of the chronicity and nonspecifi c signs, additional tests were requested. Abdominal ultrasonography showed a round mass, measuring approximately 3.7 cm x 3.2 cm, suggesting a neoplasm. Blood pressure was measured and the mean value was 152 mmHg. Laboratory tests included a complete blood count, albumin (31.62 g/L), al