Energy supplements for beef heifers on cool season pastures: a database analysis / Uso de suplemento energético para novilhas de corte em pastagens de estação fria: análise de banco de dados

Pooled data analysis is an analytical method that combines results from multiple studies. This technique provides a more robust estimate of the effects of an investigation. We performed a database analysis from seventeen experiments developed at Federal University of Santa Maria, Rio Grande do Sul state, Brazil, between 1999 and 2017 to characterize individual performance per area and stocking rate with or without supplementation of replacement heifers grazing winter pastures. Data were separated into two groups: with and without energy supplement provision, and into five subgroups based on supplement levels. Heifers from both groups were maintained under similar forage biomass and leaf blade allowance. Statistical analyses were run on R software using a 'meta' package. Supplement supply increased average daily gain and gain of body condition scores by 11.1% and 20.0%, respectively. Supplement levels higher than 1.2% of body weight resulted in higher weight gain per area, with the stocking rate increasing with higher supplement levels.

Análise conjunta de dados é um método analítico que integra os resultados de muitos estudos. Essa técnica fornece uma estimativa mais robusta sobre os efeitos de uma investigação. Com o objetivo de caracterizar o desempenho individual, por área e a taxa de lotação com uso ou não de suplementos para novilhas de reposição mantidas em pastagem de inverno, foi realizada uma análise de banco de dados de dezessete experimentos conduzidos na Universidade Federal de Santa Maria (UFSM), RS, Brasil, entre 1999 e 2017. Os dados foram estratificados em dois grupos: com e sem suplemento energético e cinco subgrupos de acordo com o nível de suplemento. As novilhas de ambos os grupos foram mantidas em similar massa de forragem e oferta de lâminas foliares. As análises estatísticas foram executadas no software R, pacote 'meta'. O fornecimento de suplemento aumentou o ganho médio diário em 11.1% e em 20.0% o ganho no escore de condição corporal. Níveis de fornecimento maiores que 1.2% do peso corporal proporcionaram o maior ganho de peso por área e a taxa de lotação aumenta à medida que os níveis de suplemento aumentam.

Composition differences between organic and conventional processed foods: a meta-analytical study / Diferenças de composição entre alimentos processados orgânicos e convencionais: um estudo meta-analítico

Comparisons between the nutritional quality of organic and conventional fresh foods are frequently reported in the literature; however, discussion about processed foods is less frequent. Therefore, this study compared the nutritional content of processed products from both production systems using a systematic review of the literature and meta-analysis, regarding aspects of raw material management and processing. The study reviewed scientific articles published between 2010 and 2020 and the data obtained were analyzed using the standardized mean difference method with Hedges' adjustment and a random analytical model. Thirty-seven articles were selected, and the foods analyzed in the studies were grouped into five categories: meat products, dairy products, caught fish, wines, and fruit juices/pulps. In products of animal origin, the comparative focus shown was mainly that of the fatty acid profile, while in those of vegetable origin it was that of phytochemicals. Related to the comparison of nutrient contents, it was possible to verify the similarities in organic and conventional products in most studies; however, specific differences were verified (P < 0.05): organics contained more proteins (meat), omega 3 (dairy), and less linoleic acid (dairy and caught fish). Also, there were differences in the management of organic and conventional raw materials, and similarities in processing. Therefore, the choice for organic processed foods should not be made exclusively based on nutritional aspects, considering that the differences in nutrient contents in relation to those of conventional products are practically nonexistent.

Frequentemente são encontradas na literatura comparações entre a qualidade nutricional dos alimentos orgânicos e convencionais in natura, no entanto, pouco se discute acerca dos processados. Assim sendo, o objetivo desse estudo foi comparar o teor nutricional dos processados de ambos os sistemas de produção utilizando uma revisão sistemática da literatura e meta-análise, associando a aspectos de manejo das matérias-primas e processamento. Para isso, buscou-se artigos científicos publicados entre 2010 e 2020 e os dados obtidos foram analisados utilizando o método da diferença média padronizada com ajuste de Hedges e modelo analítico aleatório. Trinta e sete artigos foram selecionados, e os alimentos analisados em tais estudos foram agrupados em cinco categorias: cárneos, lácteos, pescado, vinhos e sucos/polpas de frutas. Nos produtos de origem animal o foco comparativo evidenciado foi principalmente o do perfil de ácidos graxos, enquanto nos de origem vegetal foi o dos fitoquímicos. Em relação à comparação do teor de nutrientes, foi possível constatar a similaridade nos orgânicos e nos convencionais na maioria dos estudos, entretanto, diferenças pontuais foram verificadas (P < 0,05): orgânicos com mais proteínas (cárneos), ômega 3 (lácteos) e menos ácido linoleico (lácteos e pescado). Também, notaram-se diferenças no manejo das matérias-primas orgânicas e convencionais, e similaridade no processamento. Portanto, a escolha por alimentos processados orgânicos não deve ser feita exclusivamente baseada em aspectos nutricionais, tendo em vista que as diferenças nos teores dos nutrientes em relação aos convencionais são praticamente inexistentes.

Meta-analysis of melatonin treatment and porcine somatic cell nuclear transfer embryo development

Abstract Porcine somatic cell nuclear transfer (SCNT) plays an important role in many areas of research. However, the low efficiency of SCNT in porcine embryos limits its applications. Porcine embryos contain high concentrations of lipid, which makes them vulnerable to oxidative stress. Some studies have used melatonin to reduce reactive oxygen species damage. At present there are many reports concerning the effect of exogenous melatonin on porcine SCNT. Some studies suggest that the addition of melatonin can increase the number of blastocyst cells, while others indicate that melatonin can reduce the number of blastocyst cells. Therefore, a meta-analysis was carried out to resolve the contradiction. In this study, a total of 63 articles from the past 30 years were analyzed, and six papers were finally selected. Through the analysis, it was found that the blastocyst rate was increased by adding exogenous melatonin. Melatonin had no effect on cleavage rate or the number of blastocyst cells, but did decrease the number of apoptotic cells. This result is crucial for future research on embryo implantation.

Meta-analysis of melatonin treatment and porcine somatic cell nuclear transfer embryo development

Porcine somatic cell nuclear transfer (SCNT) plays an important role in many areas of research. However, the low efficiency of SCNT in porcine embryos limits its applications. Porcine embryos contain high concentrations of lipid, which makes them vulnerable to oxidative stress. Some studies have used melatonin to reduce reactive oxygen species damage. At present there are many reports concerning the effect of exogenous melatonin on porcine SCNT. Some studies suggest that the addition of melatonin can increase the number of blastocyst cells, while others indicate that melatonin can reduce the number of blastocyst cells. Therefore, a meta-analysis was carried out to resolve the contradiction. In this study, a total of 63 articles from the past 30 years were analyzed, and six papers were finally selected. Through the analysis, it was found that the blastocyst rate was increased by adding exogenous melatonin. Melatonin had no effect on cleavage rate or the number of blastocyst cells, but did decrease the number of apoptotic cells. This result is crucial for future research on embryo implantation.(AU)

Performance responses of broilers and pigs fed diets with ß-mannanase

This study was developed using meta-analysis to evaluate the effect of ß-mannanase on both poultry and pig performance. Two databases were constructed using information from previous studies that evaluated the ß-mannanase supplementation in diets for broilers (30 papers; 19,643 birds) and pigs (20 papers; 5,319 animals). The meta-analysis followed three sequential analyses: graphical, correlation, and variance-covariance. The effect of ß-mannanase supplementation on performance considerably varied in both databases. Data analysis considering the study effect showed that ß-mannanase supplementation did not influence feed intake. Diets supplemented with ß-mannanase did not influence weight gain, but improved feed conversion (−1%) of broilers compared with the control group. Feeding pigs diets supplemented with ß-mannanase improved weight gain (+5%) and feed conversion (−6%) compared with pigs fed non-supplemented diets. ß-mannanase supplementation increased the digestibility coefficient of dry matter, crude protein, and energy in both species. The inclusion of ß-mannanase also improved the metabolizable energy content in broiler diets and enhanced the digestibility of energy in pig feeds. Current results indicate that ß-mannanase can be considered as an important tool for nutritionists who search for improved feed conversions and nutrient digestibility coefficients.(AU)

Meta-analysis of brucellosis vaccinology in natural hosts / Meta-análise da vacinologia de brucelose em hospedeiros naturais

Brucellosis is a relevant zoonotic disease for which the most important tool for control is vaccination of susceptible animals. Assessment of vaccine efficacy in natural hosts is based on prevention of abortion and Brucella infection in organs of immunized animals. A meta-analysis of experimental vaccination of Brucella spp. natural hosts was performed, including 45 PubMed and/or Scopus-indexed publications, representing 116 individual experiments. Difference of risk was calculated as an indicator of protection, and a temporal analysis (1980-2016) demonstrated that experimental vaccines tested on natural hosts provided levels of protection that were stable over the past decades. The meta-regression model developed in this study included different vaccine categories (attenuated, inactivated, mutant, subunit, and vectored) considering the difference of risk as the dependent variable. The subcutaneous route of vaccination provided better protection when compared to the intramuscular and oral routes of vaccination. Surprisingly, inactivated vaccines provided better protection than live naturally attenuated vaccine strains (spontaneous mutations) that were considered the reference, whereas subunit vaccines provided lower levels of protection. This is the first meta-analysis of Brucella vaccinology in the natural hosts. These results are useful for the development of new vaccination protocols for controlling animal brucellosis.(AU)

Brucelose é uma doença zoonótica relevante, para a qual a vacinação de animais susceptíveis é a ferramenta mais importante de controle. Avaliação da eficácia vacinal em hospedeiros naturais é baseada na prevenção de aborto e da colonização de órgãos pela Brucella spp. em animais imunizados. Foi realizada meta-análise de estudos de vacinação experimental de Brucella spp. em hospedeiros naturais, incluindo 45 publicações indexadas pela PubMed e/ou Scopus, representando 116 experimentos individuais. Diferença de risco foi calculada como indicador de proteção e uma análise temporal (1980-2016) demonstrou que vacinas experimentais testadas em hospedeiros naturais promoveram níveis de proteção que foram estáveis ao longo das últimas décadas. O modelo de meta-regressão desenvolvido neste estudo incluiu diferentes categorias de vacinas (atenuada, inativada, mutante, subunidade e vetorial) considerando a diferença de risco como variável dependente. A via de vacinação subcutânea promoveu melhor proteção quando comparada às vias intramuscular e oral. Surpreendentemente, vacinas inativadas promoveram melhor proteção que vacinas vivas atenuadas (com mutações espontâneas) que foram consideradas como referência, enquanto vacinas de subunidades promoveram menor proteção. Este é o primeiro estudo de meta-análise da vacinologia de Brucella em hospedeiros naturais. Estes resultados são úteis para o desenvolvimento de novos protocolos vacinais para controle de brucelose animal.(AU)

Meta-analysis of brucellosis vaccinology in natural hosts / Meta-análise da vacinologia de brucelose em hospedeiros naturais

Brucellosis is a relevant zoonotic disease for which the most important tool for control is vaccination of susceptible animals. Assessment of vaccine efficacy in natural hosts is based on prevention of abortion and Brucella infection in organs of immunized animals. A meta-analysis of experimental vaccination of Brucella spp. natural hosts was performed, including 45 PubMed and/or Scopus-indexed publications, representing 116 individual experiments. Difference of risk was calculated as an indicator of protection, and a temporal analysis (1980-2016) demonstrated that experimental vaccines tested on natural hosts provided levels of protection that were stable over the past decades. The meta-regression model developed in this study included different vaccine categories (attenuated, inactivated, mutant, subunit, and vectored) considering the difference of risk as the dependent variable. The subcutaneous route of vaccination provided better protection when compared to the intramuscular and oral routes of vaccination. Surprisingly, inactivated vaccines provided better protection than live naturally attenuated vaccine strains (spontaneous mutations) that were considered the reference, whereas subunit vaccines provided lower levels of protection. This is the first meta-analysis of Brucella vaccinology in the natural hosts. These results are useful for the development of new vaccination protocols for controlling animal brucellosis.(AU)

Brucelose é uma doença zoonótica relevante, para a qual a vacinação de animais susceptíveis é a ferramenta mais importante de controle. Avaliação da eficácia vacinal em hospedeiros naturais é baseada na prevenção de aborto e da colonização de órgãos pela Brucella spp. em animais imunizados. Foi realizada meta-análise de estudos de vacinação experimental de Brucella spp. em hospedeiros naturais, incluindo 45 publicações indexadas pela PubMed e/ou Scopus, representando 116 experimentos individuais. Diferença de risco foi calculada como indicador de proteção e uma análise temporal (1980-2016) demonstrou que vacinas experimentais testadas em hospedeiros naturais promoveram níveis de proteção que foram estáveis ao longo das últimas décadas. O modelo de meta-regressão desenvolvido neste estudo incluiu diferentes categorias de vacinas (atenuada, inativada, mutante, subunidade e vetorial) considerando a diferença de risco como variável dependente. A via de vacinação subcutânea promoveu melhor proteção quando comparada às vias intramuscular e oral. Surpreendentemente, vacinas inativadas promoveram melhor proteção que vacinas vivas atenuadas (com mutações espontâneas) que foram consideradas como referência, enquanto vacinas de subunidades promoveram menor proteção. Este é o primeiro estudo de meta-análise da vacinologia de Brucella em hospedeiros naturais. Estes resultados são úteis para o desenvolvimento de novos protocolos vacinais para controle de brucelose animal.(AU)

Is the cat an important reservoir host for visceral leishmaniasis? A systematic review with meta-analysis

In recent years feline leishmanial infections (FLI) have been studied more than ever before in various parts of the world. However, evidence-based knowledge on FLI has remained unavailable. The main objectives of this study were to investigate the status of felines infected by Leishmania spp. worldwide. Data were extracted from 10 available databases over the period of 1982 to 2017. Overall, 78 articles fulfilled the inclusion criteria and were used for data extraction in this systematic review. The overall FLI prevalence by both serological and molecular methods was estimated at 10% (95% CI: 8%-14%). In Italy, both the seroprevalence (24 %) and PCR prevalence (21 %) were found to be higher than in other countries. The most common diagnostic test used was the indirect fluorescent antibody test (38.5%). Studies on mixed-breed felines were more common than those on other breeds, while the most common parasite species was L. infantum (63%). Our findings suggest that cats act as primary and/or secondary reservoir hosts in the transmission of the Leishmania spp. to humans and also to dogs, by sandflies, at least in endemic foci. Moreover, available data confirm the enzootic stability situation of FLI in several countries including some in Europe.(AU)

Is the cat an important reservoir host for visceral leishmaniasis? A systematic review with meta-analysis

In recent years feline leishmanial infections (FLI) have been studied more than ever before in various parts of the world. However, evidence-based knowledge on FLI has remained unavailable. The main objectives of this study were to investigate the status of felines infected by Leishmania spp. worldwide. Data were extracted from 10 available databases over the period of 1982 to 2017. Overall, 78 articles fulfilled the inclusion criteria and were used for data extraction in this systematic review. The overall FLI prevalence by both serological and molecular methods was estimated at 10% (95% CI: 8%-14%). In Italy, both the seroprevalence (24 %) and PCR prevalence (21 %) were found to be higher than in other countries. The most common diagnostic test used was the indirect fluorescent antibody test (38.5%). Studies on mixed-breed felines were more common than those on other breeds, while the most common parasite species was L. infantum (63%). Our findings suggest that cats act as primary and/or secondary reservoir hosts in the transmission of the Leishmania spp. to humans and also to dogs, by sandflies, at least in endemic foci. Moreover, available data confirm the enzootic stability situation of FLI in several countries including some in Europe.(AU)

Performance and Egg Quality of Commercial Laying Hens Fed Diets Formulated Using Non-Linear Programming

Feed formulation using linear programming consists of determining the mixture of feedstuffs required to meet pre-established animal nutritional requirements at the lowest cost. On the other hand, with the use of non-linear programming, it is possible to define nutritional requirements at the time of formulation, aiming at maximum profit. The objective of the present study was to compare feeds formulated using linear and non-linear programming in terms of live performance and internal and external egg quality of commercial laying hens. A total of 288 Hisex® White laying hens, 1.540 ± 0.128 g body weight, were evaluated from 33 to 45 weeks of age. Hens were distributed in a completely randomized block design, including six treatments with six replicates of eight birds each. Three treatments consisted of feeds formulated using linear programming and based on the nutritional requirements of Rostagno et al. (2011), of the genetic strain manual, or mathematical models to maximize performance. The other three treatments consisted of feeds formulated using non-linear programming considering typical, favorable, or unfavorable market scenarios. Data were submitted to analysis of variance, and in case of significance (p 0.05), means were grouped using the Scott-Knott test (5%).The treatments did not influence (p>0.05) Haugh unit, albumen height, or external egg quality parameters. Treatment effects (p 0.05) on yolk weight, albumen weight, yolk color, yolk percentage, albumen percentage, and performance parameters were described. In general, feeds formulated using linear programming and based on nutritional requirements obtained by mathematical models and the genetic strain manual promoted better performance results because the feeds were nutritionally denser. However, the treatments that maximized live performance did not result in higher profitability, which was obtained with the diet formulated for a favorable market scenario using non-linear programming.(AU)

Performance and Egg Quality of Commercial Laying Hens Fed Diets Formulated Using Non-Linear Programming

Feed formulation using linear programming consists of determining the mixture of feedstuffs required to meet pre-established animal nutritional requirements at the lowest cost. On the other hand, with the use of non-linear programming, it is possible to define nutritional requirements at the time of formulation, aiming at maximum profit. The objective of the present study was to compare feeds formulated using linear and non-linear programming in terms of live performance and internal and external egg quality of commercial laying hens. A total of 288 Hisex® White laying hens, 1.540 ± 0.128 g body weight, were evaluated from 33 to 45 weeks of age. Hens were distributed in a completely randomized block design, including six treatments with six replicates of eight birds each. Three treatments consisted of feeds formulated using linear programming and based on the nutritional requirements of Rostagno et al. (2011), of the genetic strain manual, or mathematical models to maximize performance. The other three treatments consisted of feeds formulated using non-linear programming considering typical, favorable, or unfavorable market scenarios. Data were submitted to analysis of variance, and in case of significance (p 0.05), means were grouped using the Scott-Knott test (5%).The treatments did not influence (p>0.05) Haugh unit, albumen height, or external egg quality parameters. Treatment effects (p 0.05) on yolk weight, albumen weight, yolk color, yolk percentage, albumen percentage, and performance parameters were described. In general, feeds formulated using linear programming and based on nutritional requirements obtained by mathematical models and the genetic strain manual promoted better performance results because the feeds were nutritionally denser. However, the treatments that maximized live performance did not result in higher profitability, which was obtained with the diet formulated for a favorable market scenario using non-linear programming.

Clinical aspects and diagnosis of leishmaniasis in equids: a systematic review and meta-analysis / Aspectos clínicos e diagnóstico da leishmaniose em equídeos: uma revisão sistemática e meta-análise

Leishmaniases are a group of diseases of zoonotic importance caused by over 20 species of protozoa of the genus Leishmania, in which domestic dogs are considered to be the main reservoir for the disease. However, the involvement of other vertebrates as reservoirs for these parasites has also been investigated. Therefore, the objective of the present study was to carry out a systematic review with meta-analysis on occurrences of leishmaniasis in equids. The case reports described animals with cutaneous symptoms of leishmaniasis (papules, nodules, ulcers or crusts) that regressed spontaneously, located mainly on the head and limbs, from which three species of protozoa were identified in the lesions: Leishmania braziliensis, Leishmania infantum and Leishmania siamensis. In turn, the meta-analysis showed a combined prevalence of 25%, although with high heterogeneity among the studies, which was attributed to the use of different methods for diagnosing the disease. Leishmaniasis in equids is a benign disease but it should be included in the differential diagnosis of cutaneous diseases among these species. Seroepidemiological studies are important in investigating and monitoring suspected exposure of these hosts to the parasite, especially in endemic areas. However, there is also a need to standardize diagnostic methods.(AU)

As leishmanioses são um grupo de doenças de importância zoonótica causadas por mais de 20 espécies de protozoários do gênero Leishmania, sendo o cão doméstico considerado o principal reservatório da doença. No entanto, diversas pesquisas têm investigado o envolvimento de outros vertebrados como reservatórios do parasita. Portanto, o objetivo do presente estudo foi realizar uma revisão sistemática com meta-análise da ocorrência de leishmaniose em equídeos. Os relatos de caso descreviam animais com sintomas cutâneos de leishmaniose (pápulas, nódulos, úlceras, crostas) que regrediam espontaneamente, localizadas principalmente na cabeça e membros, sendo identificadas três espécies do protozoário nas lesões: Leishmania braziliensis, Leishmania infantum e Leishmania siamensis. Por sua vez, a meta-análise evidenciou uma prevalência combinada de 25%, porém com alta heterogeneidade entre os estudos, atribuída às diferenças nos métodos utilizados no diagnóstico da doença. A leishmaniose em equídeos é uma doença benigna, porém deve ser incluída no diagnóstico diferencial de doenças cutâneas nessas espécies. Os estudos soroepidemiológicos são importantes para investigar e monitorar a suspeita de exposição desses hospedeiros ao parasita, principalmente em áreas endêmicas, porém há necessidade de padronização dos métodos de diagnóstico.(AU)

Probability of beef tenderness in confined cows - a meta-analytic approach / Probabilidade de maciez na carne de vacas confinadas - abordagem meta-analítica

This study aimed to assess the probability of meat tenderness in confined cows. For this purpose, CAPES and SciELO platforms were searched for papers under this subject published in Brazil between 2000 and 2015. A total of 43 articles were found, of which eleven were used. Those selected approached the finishing of confined cows and specified animal genetic group, breed, and age at experiment start. Moreover, all these studies evaluated sensory and organoleptic characteristics of meat, following the same method. Each variable was analyzed by logistic regression, using the LOGISTIC procedure of SAS. The factors were evaluated by odds ratio (OR), in which changes in the probability of meat tenderness were estimated by means of an add-on function in regression variable units. Animal age at the beginning of termination, percentages of zebuine blood and heterozygosity, and marbling score are factors that affect (p < 0.30) the chance of beef tenderness. The probabilities of obtaining a tender meat increase when age at termination beginning and zebuine genotype participation are reduced, as well as when heterozygosity (via crosses) and meat marbling score increases.(AU)

Objetivou-se avaliar a probabilidade de maciez da carne de vacas confinadas. Para isso foram avaliados todos os artigos publicados no Brasil entre os anos de 2000 a 2015 com acesso via plataforma CAPES e SciELO. Ao total foram localizados 43 artigos dos quais foram utilizados onze, que envolveram a terminação de vacas em confinamento; além de informar o grupo genético e raça dos animais, a idade das vacas ao início do período experimental e que tivessem estudado características sensoriais e organolépticas da carne seguindo a mesma metodologia. Para análise de cada variável foi utilizada a regressão logística, por meio do procedimento LOGISTIC, disponível no SAS. Os parâmetros foram avaliados pela estatística de razão de chances (odds ratio), em que a mudança nas chances de maciez foi estimada a partir da função de acréscimos nas unidades das variáveis regressoras. A idade em que as vacas iniciam a terminação, assim como o percentual de sangue zebuíno e heterozigose juntamente com o marmoreio são fatores que afetam (p < 0,30) a chance de maciez da carne das vacas. Reduzir a idade ao início da terminação e a participação de zebuíno no genótipo das vacas, aliado a aumento na heterozigose por meio de cruzamentos e incremento no marmoreio da carne, aumenta a probabilidade de vacas de descarte demonstrarem carne macia.(AU)

Probability of beef tenderness in confined cows - a meta-analytic approach / Probabilidade de maciez na carne de vacas confinadas - abordagem meta-analítica

This study aimed to assess the probability of meat tenderness in confined cows. For this purpose, CAPES and SciELO platforms were searched for papers under this subject published in Brazil between 2000 and 2015. A total of 43 articles were found, of which eleven were used. Those selected approached the finishing of confined cows and specified animal genetic group, breed, and age at experiment start. Moreover, all these studies evaluated sensory and organoleptic characteristics of meat, following the same method. Each variable was analyzed by logistic regression, using the LOGISTIC procedure of SAS. The factors were evaluated by odds ratio (OR), in which changes in the probability of meat tenderness were estimated by means of an add-on function in regression variable units. Animal age at the beginning of termination, percentages of zebuine blood and heterozygosity, and marbling score are factors that affect (p < 0.30) the chance of beef tenderness. The probabilities of obtaining a tender meat increase when age at termination beginning and zebuine genotype participation are reduced, as well as when heterozygosity (via crosses) and meat marbling score increases.

Objetivou-se avaliar a probabilidade de maciez da carne de vacas confinadas. Para isso foram avaliados todos os artigos publicados no Brasil entre os anos de 2000 a 2015 com acesso via plataforma CAPES e SciELO. Ao total foram localizados 43 artigos dos quais foram utilizados onze, que envolveram a terminação de vacas em confinamento; além de informar o grupo genético e raça dos animais, a idade das vacas ao início do período experimental e que tivessem estudado características sensoriais e organolépticas da carne seguindo a mesma metodologia. Para análise de cada variável foi utilizada a regressão logística, por meio do procedimento LOGISTIC, disponível no SAS. Os parâmetros foram avaliados pela estatística de razão de chances (odds ratio), em que a mudança nas chances de maciez foi estimada a partir da função de acréscimos nas unidades das variáveis regressoras. A idade em que as vacas iniciam a terminação, assim como o percentual de sangue zebuíno e heterozigose juntamente com o marmoreio são fatores que afetam (p < 0,30) a chance de maciez da carne das vacas. Reduzir a idade ao início da terminação e a participação de zebuíno no genótipo das vacas, aliado a aumento na heterozigose por meio de cruzamentos e incremento no marmoreio da carne, aumenta a probabilidade de vacas de descarte demonstrarem carne macia.

Laparoscopic versus open pylorus-preserving pancreatoduodenectomy. The first meta-analyse of retrospective matched cases

Purpose: To compare the safety, feasibility, and short-term clinical benefits of laparoscopic pylorus-preserving pancreaticoduodenectomy (L-PPPD) to open pylorus-preserving pancreaticoduodenectomy (O-PPPD) through retrospective matched cases. Methods: Web of Science, Cochrane, PubMed, CNKI were searched systematically identify studies published between January and December 2017 comparing L-PPPD to O-PPPD. The meta-analysis was performed by using Review Manager 5.3.Results: Two studies matched the selection criteria, including 108 (50%) cases of laparoscopic pylorus-preserving pancreaticoduodenectomy and 108(50%) cases of open pylorus-preserving pancreaticoduodenectomy. None of the included studies were randomized, which were both retrospective matched cases. There was no difference in the incidence of postoperative pancreatic fistula, blood loss, diet start and lymph nodes. However, L-PPPD has a shorter hospital stay (p=0.0003) and O-PPPD has a shorter operative time (p=0.02) and tend to decrease the delayed gastric emptying.Conclusions: The perioperative safety of laparoscopic surgery, which also has advantages of minimal invasion and shorter hospital stay, is comparable to that of open surgery. Laparoscopic surgery could be operated if the patients matched the indication and operation difficulty is not so great. However, blind pursuits of L-PPPD should be restrained because there is no essential difference between these two in terms of feasibility, safety and short-term complication.(AU)

Thoracotomy compared to laparotomy in the traumatic diaphragmatic hernia. Systematic review and proportional methanalysis

Purpose: To evaluate the most used approach to treat traumatic diaphragmatic ruptures, and in which one the requirement to assess the second cavity is more frequent.Methods: Systematic review, observational studies. Outcomes: moment of approach, most commonly via addressed and the requirement to open the other cavity. Bases searched: Lilacs, Pubmed, Embase, Clinicaltrials.gov and Web of Science. Statistical analysis: StatsDirect 3.0.121 software. Results: Sixty eight studies (2023 participants) were included. Approach in acute phase was performed four times more than in chronic phase. Approach: abdominal 65% (IC 95% 63-67%), thoracic 23% (IC 95% 21-24%), abdominal in the acute phase 75% (IC 95% 71-78%), and chronic 24% (IC 95% 19-29%), thoracic in the acute phase 12% (IC 95% 10-14%) and chronic 69% (IC 95% 63-74%). Thorax opening in the abdominal approach: 10% (95% CI 8-14%). Abdomen opening in the thoracic approach: 15% (95% CI 7-24%). Conclusions: The most common approach was the abdominal. The approach in the acute phase was more common. In the acute phase the abdominal approach is more frequent than the thoracic approach. In the chronic phase the thoracic approach is more frequent than the abdominal one. The requirement to open the second cavity was similar in both approaches.(AU)

Estudo metanalítico da resposta de gramíneas perenes de verão à adubação nitrogenada / Meta-analytic study of response of nitrogen fertilization on perennial summer grasses

O presente trabalho visou empregar um estudo metanalítico para sumarizar e analisar dados sobre adubação nitrogenada em pastagens formadas por gramíneas dos gêneros Brachiaria, Cynodon e Panicum. Foram selecionados 36 trabalhos de pesquisa realizados no Brasil nos últimos 10 anos, incluindo artigos científicos, teses e dissertações. Com base nos dados contidos nesses trabalhos, foi calculado o incremento relativo de matéria seca e de proteína bruta em relação ao tratamento controle (ausência de adubação nitrogenada) e a eficiência da utilização do nitrogênio na produção de matéria seca e proteína bruta. Os dados obtidos foram submetidos à análise de variância para efeito linear e quadrático em cada uma das variáveis dentro de cada gênero e, no caso de significância, foi realizada análise de regressão. A produção de matéria seca e de proteína bruta de forrageiras tropicais responde de forma expressiva à adubação nitrogenada, principalmente a segunda, porém o acréscimo nas doses de nitrogênio reduz a eficiência da adubação. Verificou-se uma frequente omissão de informações relevantes em trabalhos com adubação nitrogenada em pastagens.(AU)

The study aimed to employ a meta-analytic study to summarize and analyze data on nitrogen fertilization in grasslands formed by grasses of the genera Brachiaria, Cynodon and Panicum. A sample of 36 research projects carried out in Brazil in the last ten years, including scientific papers, theses and dissertations were selected. From the data contained in these works, relative dry matter and crude protein increment compared to the control treatment (absence of nitrogen fertilization) and the efficiency of nitrogen use in the production of dry matter and crude protein were calculated. Data were subjected to analysis of variance for linear and quadratic effect on each variable within each genus and, in case of significance, regression analysis was performed. The production of dry matter and crude protein of tropical forages responds greatly to nitrogen fertilization, especially the second, but the increase in nitrogen rates reduces the efficiency of fertilization. There was a frequent omission of relevant information in scientific works on nitrogen fertilization in grasslands.(AU)

Estudo metanalítico da resposta de gramíneas perenes de verão à adubação nitrogenada / Meta-analytic study of response of nitrogen fertilization on perennial summer grasses

O presente trabalho visou empregar um estudo metanalítico para sumarizar e analisar dados sobre adubação nitrogenada em pastagens formadas por gramíneas dos gêneros Brachiaria, Cynodon e Panicum. Foram selecionados 36 trabalhos de pesquisa realizados no Brasil nos últimos 10 anos, incluindo artigos científicos, teses e dissertações. Com base nos dados contidos nesses trabalhos, foi calculado o incremento relativo de matéria seca e de proteína bruta em relação ao tratamento controle (ausência de adubação nitrogenada) e a eficiência da utilização do nitrogênio na produção de matéria seca e proteína bruta. Os dados obtidos foram submetidos à análise de variância para efeito linear e quadrático em cada uma das variáveis dentro de cada gênero e, no caso de significância, foi realizada análise de regressão. A produção de matéria seca e de proteína bruta de forrageiras tropicais responde de forma expressiva à adubação nitrogenada, principalmente a segunda, porém o acréscimo nas doses de nitrogênio reduz a eficiência da adubação. Verificou-se uma frequente omissão de informações relevantes em trabalhos com adubação nitrogenada em pastagens.(AU)

The study aimed to employ a meta-analytic study to summarize and analyze data on nitrogen fertilization in grasslands formed by grasses of the genera Brachiaria, Cynodon and Panicum. A sample of 36 research projects carried out in Brazil in the last ten years, including scientific papers, theses and dissertations were selected. From the data contained in these works, relative dry matter and crude protein increment compared to the control treatment (absence of nitrogen fertilization) and the efficiency of nitrogen use in the production of dry matter and crude protein were calculated. Data were subjected to analysis of variance for linear and quadratic effect on each variable within each genus and, in case of significance, regression analysis was performed. The production of dry matter and crude protein of tropical forages responds greatly to nitrogen fertilization, especially the second, but the increase in nitrogen rates reduces the efficiency of fertilization. There was a frequent omission of relevant information in scientific works on nitrogen fertilization in grasslands.(AU)

Influence of subcutaneous fat thickness on the carcass characteristics and meat quality of beef cattle / Influência da espessura da gordura subcutânea nas características de carcaça e qualidade de carne de bovinos

The objective of this research was to examine the effect of subcutaneous fat thickness (SFT) on carcass characteristics and meat quality in 24-month-old British and crossbred British steers finished in feedlot systems. It was assessed using meta-analysis performed on data that was extracted from 46 published studies and comprising a total of 2,695 experimental units. We found that SFT was influenced by and increased linearly with hot carcass weights (HCWs) and cold carcass weights (CCWs) and their yields; moreover, the bone fraction decreased whereas the muscle and fat fractions increased with higher levels of SFT. No significant differences were detected in meat quality variables. Thus, SFT appeared to have a direct influence on HCW, CCW, and the weight and yield of bone, muscle, and fat of castrated steers. A uniform fat thickness level of 6.0 mm SFT was determined to be the standard of quality of carcasses and meat products for consumers.(AU)

O objetivo deste trabalho foi avaliar o efeito da espessura de gordura subcutânea (EGS) nas características de carcaça e qualidade de carne em novilhos, com até 24 meses de idade, britânicos ou suas cruzas terminados no sistema de confinamento. Para isso foi utilizado o sistema de meta-análise com dados extraídos de 46 artigos publicados, totalizando 2,695 unidades experimentais. Foi encontrado que a GS influencia no aumento linear no peso de carcaça quente (PCC) e fria (PCF) e em seus rendimentos. Além disso as frações de osso decaem enquanto as frações de músculo e gordura aumentam em altos níveis de GS. Não foi encontrada diferença significativa, mas variáveis de qualidade de carne. Assim a GS apresenta influência direta em PCC, PCF e nos pesos e rendimento de osso, músculo e gordura da carcaça de novilhos castrados. Um valor uniforme de gordura subcutânea de 6,00 mm é capaz de padronizar uma qualidade de carcaça e de produtos aos consumidores.(AU)

CONSUMO ALIMENTAR RESIDUAL: DESEMPENHO PRODUTIVO E CARACTERÍSTICAS PÓS-ABATE DE NOVILHOS CONFINADOS

O consumo alimentar residual é um método utilizado para medir a eficiência de utilização dos alimentos pelos animais, independentemente do nível de produção, que permite a identificação de animais que consomem menor quantidade de alimentos sem afetar o desempenho produtivo. Dessa forma, o objetivo deste estudo foi avaliar o comportamento ingestivo, a produção estimada de metano, o desempenho e características pós-abate de novilhos com baixo, médio ou alto consumo alimentar residual (CAR). Foram utilizados dados de estudos realizados no Laboratório de Bovinocultura de Corte da Universidade Federal de Santa Maria, entre 2006 a 2015, os quais compreenderam informações de 157 novilhos castrados terminados em confinamento, abatidos aos 24 meses de idade, constituídos em uma abordagem meta-analítica. Os animais pertenciam ao rebanho experimental da propriedade, sendo oriundos do cruzamento rotativo alternado entre as raças Charolês e Nelore e foram divididos em três tratamentos: Baixo - animais com valores de CAR menos meio (-0,5) desvio padrão inferiores à média geral (n=54); Médio - animais cujos valores de CAR se localizaram entre os limites dos animais de baixo e alto CAR (n=55); Alto - animais que apresentaram valores de consumo alimentar residual meio (+0,5) desvio padrão acima da média geral (n=48). Os novilhos do tratamento Alto apresentaram maior peso inicial (302,29 kg) e os do Médio menor (279,31 kg), sendo que o tratamento Baixo não diferiu (287,84 Kg). Os consumos de matéria seca absoluto e relativo e a conversão alimentar foram maiores no tratamento Alto (10,95 kg/dia, 2,99 kg/ 100 kg de peso corporal e 7,84 kg MS/ kg de ganho, respectivamente), seguidos pelo Médio (9,43 kg/dia, 2,66 kg/ 100 kg de peso corporal e 6,55 kg MS/ kg de ganho) e Baixo (8,44 kg/dia, 2,30 kg/ 100 kg de peso corporal e 6,23 kg MS/ kg de ganho). A produção diária de metano entérico estimada foi maior no tratamento Alto (248,01 L/ dia), menor no Baixo (197,03 L/ dia) e o tratamento Médio apresentou comportamento intermediário (218,46 L/dia). Novilhos com baixo CAR permaneceram, aproximadamente, 115 dias em confinamento contra 100 e 96 dias para Médio e Alto. Novilhos com Baixo CAR apresentaram maior comprimento de carcaça (125,68 cm) em relação aos com Médio CAR (123,40 cm). O peso relativo de dianteiro foi maior nos novilhos de Baixo CAR (37,22 kg/ 100 kg de carcaça fria) em comparação com o Alto (36,65 kg/ 100 kg de carcaça fria). No peso relativo de traseiro ocorreu o inverso (52,76 kg/ 100 kg de carcaça fria no tratamento Alto e 52,05 kg/ 100 kg de carcaça fria no Baixo). Animais com Baixo e Médio CAR demonstraram maior peso relativo de coração, total de gorduras internas, gordura cardíaca, renal e abomasal. Animais com Médio CAR obtiveram maior peso relativo de gordura intestinal. Enquanto animais com Médio e Alto CAR apresentaram maior peso de fígado. Já animais com Alto CAR tiveram maiores pesos relativos de pulmões, abomaso e intestinos. O marmoreio foi maior no tratamento Alto CAR (6,77 pontos), seguido pelo Médio (5,73 pontos) e menor no Baixo (4,90 pontos). Novilhos com consumo alimentar residual negativo demonstram melhor eficiência alimentar, sem apresentar prejuízos no seu desempenho produtivo, porém apresentam maior teor gordura interna e menor marmoreio na carne.

Residual feed intake is a method used to measure the efficiency of food use by animals, regardless of the level of production, which allows the identification of animals that consume less food without affecting productive performance. Thus, the objective of this study was to evaluate the ingestive behavior, the estimated methane production, the performance and postslaughter characteristics of steers with low, medium or high residual feed intake (RFI). They used data from studies in Laboratório de Bovinocultura de Corte of Federal University of Santa Maria, from 2006 to 2015, which comprised 157 steers information castrated feedlot and slaughtered at 24 months of age, made in a meta-analytical approach. The animals belonged to the experimental herd of the property, originating from the alternating rotational cross between the Charolais and Nellore breeds and were divided into three treatments: Low - animals with RFI values less than half (-0.5) standard deviation lower than the general average (n = 54); Medium - animals whose RFI values were located between the limits of low and high RFI animals (n = 55); High - animals that presented values of residual food consumption half (+0.5) standard deviation above the general average (n = 48). High treatment steers had a higher initial weight (302.29 kg) and Medium treatment steers had a lower average (279.31 kg), while the Low treatment did not differ (287.84 kg). The dry matter intake absolute and relative and feed conversion ratio were higher in the Alto treatment (10.95 kg / day, 2.99 kg / 100 kg of body weight and 7.84 kg DM / kg of gain, respectively), followed by Medium (9.43 kg / day, 2.66 kg / 100 kg of body weight and 6.55 kg DM / kg of gain) and Low (8.44 kg / day, 2.30 kg / 100 kg of weight) and 6.23 kg DM / kg gain). The estimated daily production of enteric methane was higher in the High treatment (248.01 L / day), lower in the Low treatment (197.03 L/ day) and the Medium treatment showed an intermediate behavior (218.46 L/ day). Steers with low RFI remained approximately 115 days in feedlot against 100 and 96 days for Medium and High. Low RFI steers showed longer carcass length (125.68 cm) compared to Medium RFI steers (123.40 cm). The relative weight of the forehead was higher in the Low RFI steers (37.22 kg / 100 kg cold carcass) compared to the High steers (36.65 kg / 100 kg cold carcass). In the relative rear weight, the reverse occurred (52.76 kg / 100 kg of cold carcass in Alto treatment and 52.05 kg / 100 kg of cold carcass in Low). Animals with Low and Medium RFI showed greater relative weight of heart, total internal fat, cardiac, renal and abomasal fat. Medium RFI animals obtained a higher relative weight of intestinal fat. While animals with Medium and High RFI had higher liver weight. High RFI animals had higher relative weights of lungs, abomasum and intestines. Marbling was higher in the High RFI treatment (6.77 points), followed by the Medium one (5.73 points) and lower in the Low one (4.90 points). Steers with negative residual feed intake demonstrate better-feed efficiency, without impairing their productive performance, but have a higher content of internal fat and less marbling in the meat.