Resumo
The Richeria grandis known is for its aphrodisiac properties and due to its wide empiric use well as thelack of gender Richeria studies the objective of this study was to evaluate the androgenic and anti-androgenicactivity of this plant. They were used in this study 64 male Wistar rats, castrated, divided into eight groups. Thegroups for the study of androgen activity were treated with boiling water over corn R. grandis ethanolic extractoil at doses of 75, 150 and 300 mg / kg and groups of antiandrogenic activity received corn oil, distilled waterand ethanol extract at doses of 75, 150 and 300 mg / kg associated with testosterone. It was found that theethanol extract of R. grandis in the tested doses did not differ statistically from the negative and positive controlsdid not thus demonstrating androgenic activity or antiandrogenic.(AU)
Assuntos
Animais , Ratos , Malpighiales/anatomia & histologia , Malpighiales/química , Malpighiales/fisiologia , Androgênios/administração & dosagem , Androgênios/análise , Antagonistas de Androgênios/análiseResumo
The Richeria grandis known is for its aphrodisiac properties and due to its wide empiric use well as thelack of gender Richeria studies the objective of this study was to evaluate the androgenic and anti-androgenicactivity of this plant. They were used in this study 64 male Wistar rats, castrated, divided into eight groups. Thegroups for the study of androgen activity were treated with boiling water over corn R. grandis ethanolic extractoil at doses of 75, 150 and 300 mg / kg and groups of antiandrogenic activity received corn oil, distilled waterand ethanol extract at doses of 75, 150 and 300 mg / kg associated with testosterone. It was found that theethanol extract of R. grandis in the tested doses did not differ statistically from the negative and positive controlsdid not thus demonstrating androgenic activity or antiandrogenic.