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1.
Ci. Rural ; 50(9): e20190825, July 27, 2020. graf, tab
Artigo em Inglês | VETINDEX | ID: vti-746145

Resumo

Shikimic acid (SA) has witnessed a strong increase in recent years due to the increasing demand of the pharmaceutical and cosmetic industry. The SA is used as a precursor for the synthesis of oseltamivir phosphate (Tamiflu®), a potent viral inhibitor and is extracted from the plant Illicium verum Hook which has a limited availability. This article proposed the use of Urochloa plantaginea (Link.) webster and glyphosate, as an alternative source of SA. U. plantaginea plants with 3 - 4 tillers and 4 - 6 leaves were harvest at 3, 6, 9 and 12 days after application (DAT) of low rates of glyphosate. Samples were dried, extracted, analyzed by HPLC and LC-MS/MS. The maximum SA concentrations were observed at 6 days after glyphosate at 36 g.a.e.ha-1 was applied in plants of U. plantaginea with 4 to 6 leaves. The capability of this annual gramineae to produce elevated SA levels throughout the entire biomass affords its potential for a greater yield on a per hectare basis.(AU)


O interesse pelo ácido chiquímico (SA) tem apresentado um forte incremento nos últimos anos devido à crescente demanda da indústria farmacêutica e cosmética. O SA é utilizado como um precursor para a síntese do fosfato de oseltamivir (Tamiflu®), um potente inibidor viral. Este ácido é extraído principalmente da planta Illicium verum Hook. A disponibilidade desta planta é um fator limitante para o crescimento do mercado no futuro próximo. Este artigo propõe Urochloa plantaginea (Link.) webster tratada com sub doses de glifosato, como uma fonte alternativa de SA. Plantas de U. plantaginea com 3 - 4 perfilhos e 4 a 6 folhas foram tratadas com subdoses de glifosato e coletadas aos 0, 3, 6, 9 e 12 dias após sua aplicação (DAT). As amostras foram secas, extraídas e analisadas por HPLC e confirmadas por LC-MS/MS. As concentrações máximas de SA foram observadas aos seis dias após aplicação do glifosato a 36 g.e.a.ha-1 em plantas de U. plantaginea com 4 - 6 folhas. A capacidade anual dessa gramínea para produzir níveis elevados de SA em toda a biomassa, pode ser uma fonte economicamente viável de SA.(AU)


Assuntos
Ácido Chiquímico , Herbicidas/administração & dosagem
2.
R. bras. Ci. avíc. ; 21(1): eRBCA-2019-0427, nov. 2019. tab, graf
Artigo em Inglês | VETINDEX | ID: vti-26241

Resumo

This study investigated the in-vitro antibacterial and fungicidal activities of three crude extracts of Illicium verum (absolute methanol, 50% methanol and aqueous extracts) against two Gram-positive bacteria (Staphylococcus aureus and Listeria monocytogenes), two Gram-negative bacteria (Escherichia coli and Salmonella Arizona), and two fungi (Aspergillus fumigatus and Aspergillus niger). The antibacterial action was measured using an agar disk diffusion test, and the minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) were determined. The fungicidal activity of the star anise extracts was assessed by the agar disk diffusion test, and poisoned food techniques, and the MICs and minimum fungicidal concentrations (MFCs) were determined. The Chinese star anise extracts showed antibacterial and antifungal activities against A. fumigatus. The results of this study suggest that alcoholic extracts are more active than aqueous extracts and that star anise could be used as a natural antimicrobial agent.(AU)


Assuntos
Illicium/imunologia , Illicium/microbiologia , Anticorpos Antibacterianos/administração & dosagem , Anticorpos Antibacterianos/análise , Anticorpos Antifúngicos/administração & dosagem , Anticorpos Antifúngicos/análise
3.
Rev. bras. ciênc. avic ; 21(1): eRBCA, abr. 2019. tab, graf
Artigo em Inglês | VETINDEX | ID: biblio-1490621

Resumo

This study investigated the in-vitro antibacterial and fungicidal activities of three crude extracts of Illicium verum (absolute methanol, 50% methanol and aqueous extracts) against two Gram-positive bacteria (Staphylococcus aureus and Listeria monocytogenes), two Gram-negative bacteria (Escherichia coli and Salmonella Arizona), and two fungi (Aspergillus fumigatus and Aspergillus niger). The antibacterial action was measured using an agar disk diffusion test, and the minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) were determined. The fungicidal activity of the star anise extracts was assessed by the agar disk diffusion test, and poisoned food techniques, and the MICs and minimum fungicidal concentrations (MFCs) were determined. The Chinese star anise extracts showed antibacterial and antifungal activities against A. fumigatus. The results of this study suggest that alcoholic extracts are more active than aqueous extracts and that star anise could be used as a natural antimicrobial agent.


Assuntos
Anticorpos Antibacterianos/administração & dosagem , Anticorpos Antibacterianos/análise , Anticorpos Antifúngicos/administração & dosagem , Anticorpos Antifúngicos/análise , Illicium/imunologia , Illicium/microbiologia
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